1AT1
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4E2F
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1XJW
| The Structure of E. coli Aspartate Transcarbamoylase Q137A Mutant in The R-State | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... | Authors: | Stieglitz, K.A, Alam, N, Xia, J, Gourinath, S, Tsuruta, H, Kantrowitz, E.R. | Deposit date: | 2004-09-25 | Release date: | 2005-05-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | A Single Amino Acid Substitution in the Active Site of Escherichia coli Aspartate Transcarbamoylase Prevents the Allosteric Transition. J.Mol.Biol., 349, 2005
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4EP1
| Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis | Descriptor: | Ornithine carbamoyltransferase | Authors: | Shabalin, I.G, Mikolajczak, K, Stam, J, Winsor, J, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-04-16 | Release date: | 2012-04-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Crystal structures of anabolic ornithine carbamoyltransferase from Bacillus anthracis To be Published
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4EKN
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4F04
| A Second Allosteric site in E. coli Aspartate Transcarbamoylase: R-state ATCase with UTP bound | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... | Authors: | Peterson, A.W, Cockrell, G.M, Kantrowitz, E.R. | Deposit date: | 2012-05-03 | Release date: | 2012-07-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A second allosteric site in Escherichia coli aspartate transcarbamoylase. Biochemistry, 51, 2012
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4F2G
| The Crystal Structure of Ornithine carbamoyltransferase from Burkholderia thailandensis E264 | Descriptor: | 1,2-ETHANEDIOL, Ornithine carbamoyltransferase 1, PHOSPHATE ION | Authors: | Craig, T.K, Fox, D, Staker, B, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2012-05-07 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
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1C9Y
| HUMAN ORNITHINE TRANSCARBAMYLASE: CRYSTALLOGRAPHIC INSIGHTS INTO SUBSTRATE RECOGNITION AND CATALYTIC MECHANISM | Descriptor: | NORVALINE, ORNITHINE CARBAMOYLTRANSFERASE, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER | Authors: | Shi, D, Yu, X, Morizono, H, Tuchman, M, Allewell, N.M. | Deposit date: | 1999-08-03 | Release date: | 2000-06-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of human ornithine transcarbamylase complexed with carbamoyl phosphate and L-norvaline at 1.9 A resolution. Proteins, 39, 2000
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1ZA2
| Structure of wild-type E. coli Aspartate Transcarbamoylase in the presence of CTP, carbamoyl phosphate at 2.50 A resolution | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Wang, J, Stieglitz, K.A, Cardia, J.P, Kantrowitz, E.R. | Deposit date: | 2005-04-05 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase Proc.Natl.Acad.Sci.Usa, 102, 2005
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4FYX
| E. coli Aspartate Transcarbamoylase complexed with dCTP, UTP, and Mg2+ | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ... | Authors: | Cockrell, G.M, Kantrowitz, E.R. | Deposit date: | 2012-07-05 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.0889 Å) | Cite: | Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 51, 2012
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1ZA1
| Structure of wild-type E. coli Aspartate Transcarbamoylase in the presence of CTP at 2.20 A resolution | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Wang, J, Stieglitz, K.A, Cardia, J.P, Kantrowitz, E.R. | Deposit date: | 2005-04-05 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase Proc.Natl.Acad.Sci.Usa, 102, 2005
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4FYV
| Aspartate Transcarbamoylase Complexed with dCTP | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ... | Authors: | Cockrell, G.M, Kantrowitz, E.R. | Deposit date: | 2012-07-05 | Release date: | 2012-10-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.0976 Å) | Cite: | Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 51, 2012
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4FYW
| E. coli Aspartate Transcarbamoylase complexed with CTP | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Cockrell, G.M, Kantrowitz, E.R. | Deposit date: | 2012-07-05 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 51, 2012
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1D09
| ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH N-PHOSPHONACETYL-L-ASPARTATE (PALA) | Descriptor: | ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... | Authors: | Jin, L, Stec, B, Lipscomb, W.N, Kantrowitz, E.R. | Deposit date: | 1999-09-09 | Release date: | 2000-01-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Insights into the mechanisms of catalysis and heterotropic regulation of Escherichia coli aspartate transcarbamoylase based upon a structure of the enzyme complexed with the bisubstrate analogue N-phosphonacetyl-L-aspartate at 2.1 A. Proteins, 37, 1999
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4FYY
| E. coli Aspartate Transcarbamoylase Complexed with CTP, UTP, and Mg2+ | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Cockrell, G.M, Kantrowitz, E.R. | Deposit date: | 2012-07-05 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9395 Å) | Cite: | Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 51, 2012
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2A0F
| Structure of D236A mutant E. coli Aspartate Transcarbamoylase in presence of Phosphonoacetamide at 2.90 A resolution | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, PHOSPHONOACETAMIDE, ... | Authors: | Stieglitz, K.A, Dusinberre, K.J, Cardia, J.P, Tsuruta, H, Kantrowitz, E.R. | Deposit date: | 2005-06-16 | Release date: | 2005-09-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the E.coli Aspartate Transcarbamoylase Trapped in the Middle of the Catalytic Cycle. J.Mol.Biol., 352, 2005
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1DXH
| Catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa | Descriptor: | ORNITHINE CARBAMOYLTRANSFERASE, SULFATE ION | Authors: | Sainz, G, Vicat, J, Kahn, R, Duee, E, Tricot, C, Stalon, V, Dideberg, O. | Deposit date: | 2000-01-05 | Release date: | 2001-01-12 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the Allosteric Active Form of Catabolic Ornithine Carbamoyltransferase from Pseudomonas Aeruginosa To be Published
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1DUV
| CRYSTAL STRUCTURE OF E. COLI ORNITHINE TRANSCARBAMOYLASE COMPLEXED WITH NDELTA-L-ORNITHINE-DIAMINOPHOSPHINYL-N-SULPHONIC ACID (PSORN) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, NDELTA-(N'-SULPHODIAMINOPHOSPHINYL)-L-ORNITHINE, ORNITHINE TRANSCARBAMOYLASE | Authors: | Langley, D.B, Templeton, M.D, Fields, B.A, Mitchell, R.E, Collyer, C.A. | Deposit date: | 2000-01-18 | Release date: | 2000-07-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of inactivation of ornithine transcarbamoylase by Ndelta -(N'-Sulfodiaminophosphinyl)-L-ornithine, a true transition state analogue? Crystal structure and implications for catalytic mechanism. J.Biol.Chem., 275, 2000
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4H31
| Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with carbamoyl phosphate and L-norvaline | Descriptor: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Shabalin, I.G, Winsor, J, Grimshaw, S, Osinski, T, Chordia, M.D, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-09-13 | Release date: | 2012-09-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural studies of ornithine carbamoyltransferase from various pathogens To be Published
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2AT1
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1EP9
| HUMAN ORNITHINE TRANSCARBAMYLASE: CRYSTALLOGRAPHIC INSIGHTS INTO SUBSTRATE RECOGNITION AND CONFORMATIONAL CHANGE | Descriptor: | ORNITHINE TRANSCARBAMYLASE, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER | Authors: | Shi, D, Morizono, H, Yu, X, Allewell, N.M, Tuchman, M. | Deposit date: | 2000-03-28 | Release date: | 2001-04-04 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changes. Biochem.J., 354, 2001
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2ATC
| CRYSTAL AND MOLECULAR STRUCTURES OF NATIVE AND CTP-LIGANDED ASPARTATE CARBAMOYLTRANSFERASE FROM ESCHERICHIA COLI | Descriptor: | ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN, REGULATORY CHAIN, ... | Authors: | Honzatko, R.B, Crawford, J.L, Monaco, H.L, Ladner, J.E, Edwards, B.F.P, Evans, D.R, Warren, S.G, Wiley, D.C, Ladner, R.C, Lipscomb, W.N. | Deposit date: | 1982-03-24 | Release date: | 1982-12-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal and molecular structures of native and CTP-liganded aspartate carbamoyltransferase from Escherichia coli. J.Mol.Biol., 160, 1982
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1EKX
| THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE) | Descriptor: | ASPARTATE TRANSCARBAMOYLASE, CALCIUM ION, N-(PHOSPHONACETYL)-L-ASPARTIC ACID | Authors: | Endrizzi, J.A, Beernink, P.T, Alber, T, Schachman, H.K. | Deposit date: | 2000-03-09 | Release date: | 2000-05-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation induced cell migration. Proc.Natl.Acad.Sci.USA, 97, 2000
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2AIR
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2AT2
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