6MTD
 
 | | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | Deposit date: | 2018-10-19 | | Release date: | 2018-11-21 | | Last modified: | 2019-05-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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6MTE
 | | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | Deposit date: | 2018-10-19 | | Release date: | 2018-11-21 | | Last modified: | 2019-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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7MDZ
 | | 80S rabbit ribosome stalled with benzamide-CHX | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S21, ... | | Authors: | Koga, Y, Hoang, E.M, Park, Y, Keszei, A.F.A, Murray, J, Shao, S, Liau, B.B. | | Deposit date: | 2021-04-06 | | Release date: | 2021-09-01 | | Last modified: | 2021-09-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation.
J.Am.Chem.Soc., 143, 2021
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7NFX
 | | Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A | | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Jomaa, A, Lee, J.H, Shan, S, Ban, N. | | Deposit date: | 2021-02-08 | | Release date: | 2021-06-02 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.
Sci Adv, 7, 2021
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7NWG
 | | Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. | | Descriptor: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... | | Authors: | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | | Deposit date: | 2021-03-16 | | Release date: | 2021-07-07 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021
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7NWH
 | | Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. | | Descriptor: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... | | Authors: | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | | Deposit date: | 2021-03-16 | | Release date: | 2021-07-07 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021
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7NWI
 | | Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ... | | Authors: | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | | Deposit date: | 2021-03-16 | | Release date: | 2021-07-07 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021
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7OBR
 | | RNC-SRP early complex | | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Jomaa, A, Ban, N. | | Deposit date: | 2021-04-23 | | Release date: | 2021-07-21 | | Last modified: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle.
Cell Rep, 36, 2021
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7OHX
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7OHS
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7OHW
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7OLC
 | | Thermophilic eukaryotic 80S ribosome at idle POST state | | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | Authors: | Kisonaite, M, Wild, K, Sinning, I. | | Deposit date: | 2021-05-19 | | Release date: | 2022-01-26 | | Last modified: | 2022-04-06 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
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7OLD
 | | Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state | | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | Authors: | Kisonaite, M, Wild, K, Sinning, I. | | Deposit date: | 2021-05-19 | | Release date: | 2022-01-26 | | Last modified: | 2022-02-09 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
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7OYC
 | | Cryo-EM structure of the Xenopus egg 80S ribosome | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | | Deposit date: | 2021-06-24 | | Release date: | 2022-07-20 | | Last modified: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg.
Nature, 613, 2023
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7OYD
 | | Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | | Deposit date: | 2021-06-24 | | Release date: | 2022-07-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg.
Nature, 613, 2023
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6CB1
 | | Yeast nucleolar pre-60S ribosomal subunit (state 3) | | Descriptor: | 35S pre-ribosomal RNA miscRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | | Authors: | Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. | | Deposit date: | 2018-02-01 | | Release date: | 2018-03-14 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Modular assembly of the nucleolar pre-60S ribosomal subunit.
Nature, 556, 2018
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6D9J
 | | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1. | | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | Authors: | Pisareva, V.P, Pisarev, A.V, Fernandez, I.S. | | Deposit date: | 2018-04-30 | | Release date: | 2018-06-06 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES.
Elife, 7, 2018
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6D90
 | | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1. | | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | Authors: | Pisareva, V.P, Pisarev, A.V, Fernandez, I.S. | | Deposit date: | 2018-04-27 | | Release date: | 2018-06-06 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES.
Elife, 7, 2018
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6EM5
 | | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | Descriptor: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | | Authors: | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-27 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
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6EM1
 | | State C (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | Authors: | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-27 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
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6EM3
 | | State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | Authors: | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-27 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
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6EM4
 | | State B architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | Authors: | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-27 | | Last modified: | 2018-03-21 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
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6FTI
 | | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome | | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Braunger, K, Becker, T, Beckmann, R. | | Deposit date: | 2018-02-22 | | Release date: | 2018-03-21 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Science, 360, 2018
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6FTG
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6FTJ
 | | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Non-programmed 80S Ribosome | | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Braunger, K, Becker, T, Beckmann, R. | | Deposit date: | 2018-02-22 | | Release date: | 2018-03-21 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Science, 360, 2018
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