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3K2S
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BU of 3k2s by Molmil
Solution structure of double super helix model
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Apolipoprotein A-I, CHOLESTEROL
Authors:Wu, Z, Gogonea, V, Lee, X, Wagner, M.A, Li, X.-M, Huang, Y, Undurti, A, May, R.P, Haertlein, M, Moulin, M, Gutsche, I, Zaccai, G, Didonato, J.A, Hazen, L.S.
Deposit date:2009-09-30
Release date:2010-04-07
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:Double superhelix model of high density lipoprotein.
J.Biol.Chem., 284, 2009
7UVJ
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BU of 7uvj by Molmil
Rationally Designed ED1 Epitope-Scaffold Immunogen for SARS-CoV-2
Descriptor: ACETATE ION, Apolipoprotein E, DI(HYDROXYETHYL)ETHER, ...
Authors:Yennawar, N.H, Vishweshwaraiah, Y.L, Dokholyan, N.V.
Deposit date:2022-05-02
Release date:2022-10-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Adaptation-proof SARS-CoV-2 vaccine design.
Adv Funct Mater, 32, 2022
6NCN
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BU of 6ncn by Molmil
Fragment-based Discovery of an apoE4 Stabilizer
Descriptor: 1-(3-chlorophenyl)cyclobutane-1-carboximidamide, Apolipoprotein E
Authors:Jakob, C.G, Qiu, W.
Deposit date:2018-12-11
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.
J.Med.Chem., 62, 2019
1YA9
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BU of 1ya9 by Molmil
Crystal Structure of the 22kDa N-Terminal Fragment of Mouse Apolipoprotein E
Descriptor: Apolipoprotein E
Authors:Peters-Libeu, C.A, Rutenber, E, Newhouse, Y, Hatters, D.M, Weisgraber, K.H.
Deposit date:2004-12-17
Release date:2005-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Engineering conformational destabilization into mouse apolipoprotein E. A model for a unique property of human apolipoprotein E4
J.Biol.Chem., 280, 2005
2KC3
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BU of 2kc3 by Molmil
NMR solution structure of complete receptor binding domain of human apolipoprotein E
Descriptor: Apolipoprotein E
Authors:Wang, J, Sivashanmugam, A.
Deposit date:2008-12-15
Release date:2009-04-14
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:A complete receptor binding domain of human apolipoprotein E
To be Published
1LPE
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BU of 1lpe by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE LDL RECEPTOR-BINDING DOMAIN OF HUMAN APOLIPOPROTEIN E
Descriptor: APOLIPOPROTEIN E3
Authors:Wilson, C, Agard, D.A.
Deposit date:1991-08-22
Release date:1992-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E.
Science, 252, 1991
6NCO
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BU of 6nco by Molmil
Fragment-based Discovery of an apoE4 Stabilizer
Descriptor: 1-[5-chloro-4'-(2-hydroxypropan-2-yl)[1,1'-biphenyl]-3-yl]cyclobutane-1-carboximidamide, Apolipoprotein E
Authors:Jakob, C.G, Qiu, W.
Deposit date:2018-12-11
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.707 Å)
Cite:Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.
J.Med.Chem., 62, 2019
1LE2
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BU of 1le2 by Molmil
STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E
Descriptor: APOLIPOPROTEIN E2
Authors:Wilson, C, Agard, D.A.
Deposit date:1991-08-22
Release date:1992-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein.
Structure, 2, 1994
1GS9
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BU of 1gs9 by Molmil
Apolipoprotein E4, 22k domain
Descriptor: APOLIPOPROTEIN E
Authors:Verderame, J.R, Kantardjieff, K, Segelke, B, Weisgraber, K, Rupp, B.
Deposit date:2002-01-02
Release date:2003-06-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the 22K Domain of Human Apolipoprotein E4
To be Published
3R2P
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BU of 3r2p by Molmil
2.2 Angstrom Crystal Structure of C Terminal Truncated Human Apolipoprotein A-I Reveals the Assembly of HDL by Dimerization.
Descriptor: Apolipoprotein A-I
Authors:Mei, X, Atkinson, D.
Deposit date:2011-03-14
Release date:2011-09-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2045 Å)
Cite:Crystal Structure of C-terminal Truncated Apolipoprotein A-I Reveals the Assembly of High Density Lipoprotein (HDL) by Dimerization.
J.Biol.Chem., 286, 2011
1EA8
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BU of 1ea8 by Molmil
Apolipoprotein E3 22kD fragment LYS146GLU mutant
Descriptor: APOLIPOPROTEIN E
Authors:Rupp, B, Peters-Libeu, C, Verderame, J.
Deposit date:2001-07-11
Release date:2001-07-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Apolipoprotein E3 22Kd Fragment Lys146Gln Mutant
To be Published
7FCR
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BU of 7fcr by Molmil
Crystal structure of the N-terminal domain of mutants of Human Apolipoprotein-E (ApoE)
Descriptor: Apolipoprotein E, SODIUM ION
Authors:Cherakara, S, Kumar, A, Garai, K, Ghosh, B.
Deposit date:2021-07-15
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the N-terminal domain of mutants of Human Apolipoprotein-E (ApoE)
To be published
7FCS
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BU of 7fcs by Molmil
Crystal structure of the N-terminal domain of mutants of Human Apolipoprotein-E (ApoE)
Descriptor: Apolipoprotein E, SODIUM ION
Authors:Cherakara, S, Kumar, A, Garai, K, Ghosh, B.
Deposit date:2021-07-15
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the N-terminal domain of mutants of Human Apolipoprotein-E (ApoE)
To be published
3S84
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BU of 3s84 by Molmil
Dimeric apoA-IV
Descriptor: Apolipoprotein A-IV, SULFATE ION
Authors:Deng, X, Davidson, W.S, Thompson, T.B.
Deposit date:2011-05-27
Release date:2012-05-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of Dimeric Apolipoprotein A-IV and Its Mechanism of Self-Association.
Structure, 20, 2012
1LE4
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BU of 1le4 by Molmil
STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E
Descriptor: APOLIPOPROTEIN E4
Authors:Wilson, C, Agard, D.A.
Deposit date:1991-08-22
Release date:1992-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms.
J.Biol.Chem., 269, 1994
1H7I
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BU of 1h7i by Molmil
Apolipoprotein E3 22kD fragment LYS146GLN mutant
Descriptor: APOLIPOPROTEIN E
Authors:Rupp, B, Peters-Libeu, C, Verderame, J.
Deposit date:2001-07-08
Release date:2001-07-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Apolipoprotein E3 22Kd Fragment Lys146Gln Mutant
To be Published
1AV1
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BU of 1av1 by Molmil
CRYSTAL STRUCTURE OF HUMAN APOLIPOPROTEIN A-I
Descriptor: APOLIPOPROTEIN A-I
Authors:Borhani, D.W, Rogers, D.P, Engler, J.A, Brouillette, C.G.
Deposit date:1997-09-23
Release date:1998-02-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation.
Proc.Natl.Acad.Sci.USA, 94, 1997
1B68
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BU of 1b68 by Molmil
APOLIPOPROTEIN E4 (APOE4), 22K FRAGMENT
Descriptor: APOLIPOPROTEIN E
Authors:Rupp, B, Peters-Libeu, C.
Deposit date:1999-01-21
Release date:2001-07-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction of the N-terminal domain of apolipoprotein E4 with heparin.
Biochemistry, 40, 2001
1BZ4
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BU of 1bz4 by Molmil
APOLIPOPROTEIN E3 (APO-E3), TRUNCATION MUTANT 165
Descriptor: PROTEIN (APOLIPOPROTEIN E)
Authors:Rupp, B, Segelke, B.
Deposit date:1998-11-05
Release date:1998-11-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding.
Protein Sci., 9, 2000
6V7M
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BU of 6v7m by Molmil
Crystal structure of a proteolytically cleaved, amino terminal domain of apolipoprotein E3
Descriptor: Apolipoprotein E, PHOSPHATE ION
Authors:McPherson, A.
Deposit date:2019-12-08
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a proteolytically cleaved, amino terminal domain of apolipoprotein E3.
Biochem.Biophys.Res.Commun., 2020
1OR2
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BU of 1or2 by Molmil
APOLIPOPROTEIN E3 (APOE3) TRUNCATION MUTANT 165
Descriptor: APOLIPOPROTEIN E
Authors:Rupp, B, Segelke, B.W, Forstner, M.
Deposit date:1999-03-25
Release date:2000-04-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding.
Protein Sci., 9, 2000
1NFN
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BU of 1nfn by Molmil
APOLIPOPROTEIN E3 (APOE3)
Descriptor: APOLIPOPROTEIN E3
Authors:Rupp, B, Parkin, S.
Deposit date:1996-07-17
Release date:1997-01-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia.
Nat.Struct.Biol., 3, 1996
1OR3
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BU of 1or3 by Molmil
APOLIPOPROTEIN E3 (APOE3), TRIGONAL TRUNCATION MUTANT 165
Descriptor: PROTEIN (APOLIPOPROTEIN E)
Authors:Rupp, B, Segelke, B.W.
Deposit date:1998-12-01
Release date:2000-05-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding.
Protein Sci., 9, 2000
1NFO
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BU of 1nfo by Molmil
APOLIPOPROTEIN E2 (APOE2, D154A MUTATION)
Descriptor: APOLIPOPROTEIN E2
Authors:Rupp, B, Parkin, S.
Deposit date:1996-07-17
Release date:1997-01-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia.
Nat.Struct.Biol., 3, 1996
2LEM
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BU of 2lem by Molmil
Monomeric Mouse ApoAI(1-216)
Descriptor: Apolipoprotein A-I
Authors:Chen, J, Wang, J, Yang, Y.
Deposit date:2011-06-17
Release date:2012-12-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR Structure of Mouse ApoAI(1-216)
To be Published

 

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