1LE2

STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E

Summary for 1LE2

Entry DOI	10.2210/pdb1le2/pdb
Descriptor	APOLIPOPROTEIN E2 (1 entity in total)
Functional Keywords	lipoprotein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02649
Total number of polymer chains	1
Total formula weight	16689.03
Authors	Wilson, C.,Agard, D.A. (deposition date: 1991-08-22, release date: 1992-10-15, Last modification date: 2024-02-14)
Primary citation	Wilson, C.,Mau, T.,Weisgraber, K.H.,Wardell, M.R.,Mahley, R.W.,Agard, D.A. Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein. Structure, 2:713-718, 1994 Cited by PubMed: 7994571 DOI: 10.1016/S0969-2126(00)00072-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation