PDB: 36 件ウェブページステータス検索Chemie searchBIRD

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5V9P	Crystal structure of pyrrolidine amide inhibitor [(3S)-3-(4-bromo-1H-pyrazol-1-yl)pyrrolidin-1-yl][3-(propan-2-yl)-1H-pyrazol-5-yl]methanone (compound 35) in complex with KDM5A 分子名称: Lysine-specific demethylase 5A, NICKEL (II) ION, SULFATE ION, ... 著者 Kiefer, J.R, Liang, J, Vinogradova, M. 登録日 2017-03-23 公開日 2017-05-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
5V9T	Crystal structure of selective pyrrolidine amide KDM5a inhibitor N-{(3R)-1-[3-(propan-2-yl)-1H-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide (compound 48) 分子名称: Lysine-specific demethylase 5A, N-{(3R)-1-[3-(propan-2-yl)-1H-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide, NICKEL (II) ION, ... 著者 Kiefer, J.R, Liang, J, Vinogradova, M. 登録日 2017-03-23 公開日 2017-05-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
6UXW	SWI/SNF nucleosome complex with ADP-BeFx 分子名称: 601 sequence bottom strand, 601 sequence top strand, ADENOSINE-5'-DIPHOSPHATE, ... 著者 He, Y, Han, Y. 登録日 2019-11-08 公開日 2020-03-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (8.96 Å) 主引用文献 Cryo-EM structure of SWI/SNF complex bound to a nucleosome. Nature, 579, 2020
6UXV	SWI/SNF Body Module 分子名称: SWI/SNF chromatin-remodeling complex subunit SNF5, SWI/SNF chromatin-remodeling complex subunit SWI1, SWI/SNF complex subunit SWI3, ... 著者 He, Y, Han, Y. 登録日 2019-11-08 公開日 2020-03-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Cryo-EM structure of SWI/SNF complex bound to a nucleosome. Nature, 579, 2020
7VDV	The overall structure of human chromatin remodeling PBAF-nucleosome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2, Actin, ... 著者 Chen, Z.C, Chen, K.J, Yuan, J.J. 登録日 2021-09-07 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of human chromatin-remodelling PBAF complex bound to a nucleosome. Nature, 605, 2022
7C4J	Cryo-EM structure of the yeast Swi/Snf complex in a nucleosome free state 分子名称: Actin-like protein ARP9, Actin-related protein 7, Regulator of Ty1 transposition protein 102, ... 著者 Wang, C.C, Guo, Z.Y, Zhan, X.C, Zhang, X.F. 登録日 2020-05-18 公開日 2020-07-15 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structure of the yeast Swi/Snf complex in a nucleosome free state Nat Commun, 2020
7EGM	The SRM module of SWI/SNF-nucleosome complex 分子名称: SWI/SNF chromatin-remodeling complex subunit SNF5, SWI/SNF chromatin-remodeling complex subunit SWI1, SWI/SNF complex subunit SWI3, ... 著者 Chen, Z.C, Chen, K.J, He, Z.Y, Ye, Y.P. 登録日 2021-03-24 公開日 2022-01-12 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity. Cell Discov, 7, 2021
7EGP	The structure of SWI/SNF-nucleosome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP9, Actin-related protein 7, ... 著者 Chen, Z.C, Chen, K.J, He, Z.Y, Ye, Y.P. 登録日 2021-03-24 公開日 2022-01-12 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity. Cell Discov, 7, 2021
7Y8R	The nucleosome-bound human PBAF complex 分子名称: ACTB protein (Fragment), ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2, ... 著者 Wang, L, Yu, J, Yu, Z, Wang, Q, He, S, Xu, Y. 登録日 2022-06-24 公開日 2022-12-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structure of nucleosome-bound human PBAF complex. Nat Commun, 13, 2022
6LTH	Structure of human BAF Base module 分子名称: AT-rich interactive domain-containing protein 1A, SWI/SNF complex subunit SMARCC2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, ... 著者 He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. 登録日 2020-01-22 公開日 2020-02-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of nucleosome-bound human BAF complex. Science, 367, 2020
6LTJ	Structure of nucleosome-bound human BAF complex 分子名称: AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ... 著者 He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. 登録日 2020-01-22 公開日 2020-02-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of nucleosome-bound human BAF complex. Science, 367, 2020

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