6QER
 
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5JUB
 | | Crystal structure of ComR from S.thermophilus in complex with DNA and its signalling peptide ComS. | | Descriptor: | ComS, Transcriptional regulator, pComX-for, ... | | Authors: | Talagas, A, Fontaine, L, Ledesma-Garcia, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S. | | Deposit date: | 2016-05-10 | | Release date: | 2016-10-26 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
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5JUF
 | | Crystal structure of the apo form of ComR from S. thermophilus. | | Descriptor: | SULFATE ION, Transcriptional regulator | | Authors: | Talagas, A, Fontaine, L, Ledesma, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S. | | Deposit date: | 2016-05-10 | | Release date: | 2016-10-26 | | Last modified: | 2016-12-14 | | Method: | X-RAY DIFFRACTION (1.946 Å) | | Cite: | Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
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7ZCV
 | | Rgg144 of Streptococcus pneumoniae | | Descriptor: | Transcriptional regulator | | Authors: | Wallis, R, Girija, U.V, Yesilkaya, H. | | Deposit date: | 2022-03-29 | | Release date: | 2022-06-01 | | Last modified: | 2022-07-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure-function analysis for the development of peptide inhibitors for a Gram-positive quorum sensing system.
Mol.Microbiol., 117, 2022
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7JVT
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5K98
 | | Structure of HipA-HipB-O2-O3 complex | | Descriptor: | Antitoxin HipB, DNA (5'-D(*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*G)-3'), ... | | Authors: | Schumacher, M. | | Deposit date: | 2016-05-31 | | Release date: | 2016-06-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.99 Å) | | Cite: | HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature, 524, 2015
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6F8S
 | | Toxin-Antitoxin complex GraTA | | Descriptor: | DI(HYDROXYETHYL)ETHER, Putative Killer protein, SULFATE ION, ... | | Authors: | Talavera, A, Loris, R. | | Deposit date: | 2017-12-13 | | Release date: | 2018-07-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.
Nat Commun, 10, 2019
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5W4N
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5W4M
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6TRI
 | | CI-MOR repressor-antirepressor complex of the temperate bacteriophage TP901-1 from Lactococcus lactis | | Descriptor: | CI, MOR, SULFATE ION | | Authors: | Rasmussen, K.K, Blackledge, M, Herrmann, T, Jensen, M.R, Lo Leggio, L. | | Deposit date: | 2019-12-18 | | Release date: | 2020-08-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.277 Å) | | Cite: | Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6U0I
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6KMQ
 | | 2.3 Angstrom resolution structure of dimeric HigBA toxin-antitoxin complex from E. coli | | Descriptor: | Antitoxin HigA, mRNA interferase toxin HigB | | Authors: | Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. | | Deposit date: | 2019-07-31 | | Release date: | 2020-11-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
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6KML
 | | 2.09 Angstrom resolution crystal structure of tetrameric HigBA toxin-antitoxin complex from E.coli | | Descriptor: | Antitoxin HigA, mRNA interferase toxin HigB | | Authors: | Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. | | Deposit date: | 2019-07-31 | | Release date: | 2020-11-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.095 Å) | | Cite: | 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
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3WOA
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7AB5
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7AB3
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7AB4
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3ZKC
 | | Crystal structure of the master regulator for biofilm formation SinR in complex with DNA. | | Descriptor: | 5'-D(*AP*AP*AP*GP*TP*TP*CP*TP*CP*TP*TP*TP*AP*GP *AP*GP*AP*AP*CP*AP*AP)-3', 5'-D(*AP*TP*TP*GP*TP*TP*CP*TP*CP*TP*AP*AP*AP*GP *AP*GP*AP*AP*CP*TP*TP)-3', HTH-TYPE TRANSCRIPTIONAL REGULATOR SINR | | Authors: | Newman, J.A, Rodrigues, C, Lewis, R.J. | | Deposit date: | 2013-01-22 | | Release date: | 2013-03-06 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Molecular Basis of the Activity of Sinr, the Master Regulator of Biofilm Formation in Bacillus Subtilis.
J.Biol.Chem., 288, 2013
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4J1X
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4J1W
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1RIO
 | | Structure of bacteriophage lambda cI-NTD in complex with sigma-region4 of Thermus aquaticus bound to DNA | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 27-MER, CALCIUM ION, ... | | Authors: | Jain, D, Nickels, B.E, Sun, L, Hochschild, A, Darst, S.A. | | Deposit date: | 2003-11-17 | | Release date: | 2004-01-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of a ternary transcription activation complex.
Mol.Cell, 13, 2004
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4PU3
 | | Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P212121) | | Descriptor: | Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family | | Authors: | Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S. | | Deposit date: | 2014-03-12 | | Release date: | 2014-08-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.39 Å) | | Cite: | The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
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5YCL
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4PU4
 | | Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P21) | | Descriptor: | Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family | | Authors: | Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S. | | Deposit date: | 2014-03-12 | | Release date: | 2014-08-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.786 Å) | | Cite: | The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
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6AF4
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