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1W0H
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BU of 1w0h by Molmil
Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP
Descriptor: 3'-5' EXONUCLEASE ERI1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION
Authors:Cheng, Y, Patel, D.
Deposit date:2004-06-04
Release date:2004-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Crystallographic Structure of the Nuclease Domain of 3'Hexo, a Deddh Family Member, Bound to Ramp
J.Mol.Biol., 343, 2004
7YW5
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BU of 7yw5 by Molmil
Crystal Structure of the ITS1 processing by human ribonuclease ISG20L2 with mutation D327A
Descriptor: Interferon-stimulated 20 kDa exonuclease-like 2
Authors:Yang, X.Y, Liu, X.H.
Deposit date:2022-08-21
Release date:2024-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA.
Nucleic Acids Res., 52, 2024
7T2S
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BU of 7t2s by Molmil
Structure of E. coli upec-117 Cap18 3'-5' exonuclease
Descriptor: 3'-5' exonuclease, ACETATE ION
Authors:Liang, Q, Richey, S.T, Ye, Q, Lau, R.K, Corbett, K.D.
Deposit date:2021-12-06
Release date:2022-07-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structure and activity of a bacterial defense-associated 3'-5' exonuclease.
Protein Sci., 31, 2022
5Z9X
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BU of 5z9x by Molmil
Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 in complex with an RNA substrate
Descriptor: MAGNESIUM ION, RNA (5'-R(P*GP*CP*CP*CP*AP*UP*UP*AP*G)-3'), SULFATE ION, ...
Authors:Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Gan, J, Cao, C, Huang, Y, Chen, X, Ma, J.
Deposit date:2018-02-05
Release date:2018-06-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
5CY4
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BU of 5cy4 by Molmil
Crystal structure of an oligoribonuclease from Acinetobacter baumannii
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Oligoribonuclease
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-07-30
Release date:2015-08-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of an oligoribonuclease from Acinetobacter baumannii
To Be Published
2F96
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BU of 2f96 by Molmil
2.1 A crystal structure of Pseudomonas aeruginosa rnase T (Ribonuclease T)
Descriptor: MAGNESIUM ION, Ribonuclease T
Authors:Zheng, H, Chruszcz, M, Cymborowski, M, Wang, Y, Gorodichtchenskaia, E, Skarina, T, Guthrie, J, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-12-05
Release date:2006-02-14
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover.
Structure, 15, 2007
3CG7
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BU of 3cg7 by Molmil
Crystal structure of cell-death related nuclease 4 (CRN-4)
Descriptor: Cell death-related nuclease 4, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-05
Release date:2008-12-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
7N8W
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BU of 7n8w by Molmil
Crystal structure of ERI2 nuclease bound to rAMP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 2, ...
Authors:Thapar, R, Arvai, A.S, Tainer, J.A.
Deposit date:2021-06-15
Release date:2022-07-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of ERI2 nuclease bound to rAMP
To Be Published
7N8V
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BU of 7n8v by Molmil
Crystal structure of free ERI2 nuclease
Descriptor: ERI1 exoribonuclease 2, SULFATE ION
Authors:Thapar, R, Arvai, A.S, Tainer, J.A.
Deposit date:2021-06-15
Release date:2022-07-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of free ERI2 nuclease
To Be Published
3CM6
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BU of 3cm6 by Molmil
Crystal structure of cell-death related nuclease 4 (CRN-4) bound with Er
Descriptor: Cell death-related nuclease 4, ERBIUM (III) ION, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
3CM5
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BU of 3cm5 by Molmil
Crystal structure of Cell-Death Related Nuclease 4 (CRN-4) bound with Mn
Descriptor: Cell death-related nuclease 4, MANGANESE (II) ION, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
7LPY
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BU of 7lpy by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2021-02-12
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
7LPZ
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BU of 7lpz by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2021-02-12
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
7LQ0
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BU of 7lq0 by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2021-02-12
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
1J53
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BU of 1j53 by Molmil
Structure of the N-terminal Exonuclease Domain of the Epsilon Subunit of E.coli DNA Polymerase III at pH 8.5
Descriptor: 1,2-ETHANEDIOL, DNA polymerase III, epsilon chain, ...
Authors:Hamdan, S, Carr, P.D, Brown, S.E, Ollis, D.L, Dixon, N.E.
Deposit date:2002-01-22
Release date:2002-10-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
Structure, 10, 2002
7K06
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BU of 7k06 by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, ERI1 exoribonuclease 3, MAGNESIUM ION
Authors:Thapar, R, Arvai, A.S, Tainer, J.A.
Deposit date:2020-09-03
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3'- 5' exoribonucleases
To Be Published
7K07
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BU of 7k07 by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, MANGANESE (II) ION
Authors:Thapar, R, Arvai, A.S, Tainer, J.A.
Deposit date:2020-09-03
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3'- 5' exoribonucleases
To Be Published
7K05
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BU of 7k05 by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2020-09-03
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
1J9A
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BU of 1j9a by Molmil
OLIGORIBONUCLEASE
Descriptor: OLIGORIBONUCLEASE, SULFATE ION
Authors:Bonander, N, Tordova, M, Ladner, J.E, Eisenstein, E, Gilliland, G.L, Structure 2 Function Project (S2F)
Deposit date:2001-05-24
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Crystal Structure of Haemophilus Influenzae HI1715, an Oligoribonuclease
To be Published
2XRI
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BU of 2xri by Molmil
Crystal structure of human ERI1 exoribonuclease 3
Descriptor: ERI1 EXORIBONUCLEASE 3, GLYCEROL, MAGNESIUM ION
Authors:Welin, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P.
Deposit date:2010-09-15
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Human Eri1 Exoribonuclease 3
To be Published
6J7Y
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BU of 6j7y by Molmil
Human mitochondrial Oligoribonuclease in complex with DNA
Descriptor: DNA (5'-D(P*TP*T)-3'), MAGNESIUM ION, Oligoribonuclease, ...
Authors:Chu, L.Y, Agrawal, S, Yuan, H.S.
Deposit date:2019-01-18
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Structural insights into nanoRNA degradation by human Rexo2.
Rna, 25, 2019
6J80
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BU of 6j80 by Molmil
Human mitochondrial Oligoribonuclease in complex with poly-dT DNA
Descriptor: CITRIC ACID, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
Authors:Chu, L.Y, Agrawal, S, Yuan, H.S.
Deposit date:2019-01-18
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.812 Å)
Cite:Structural insights into nanoRNA degradation by human Rexo2.
Rna, 25, 2019
6J7Z
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BU of 6j7z by Molmil
Human mitochondrial Oligoribonuclease in complex with RNA
Descriptor: CITRIC ACID, MAGNESIUM ION, Oligoribonuclease, ...
Authors:Chu, L.Y, Agrawal, S, Yuan, H.S.
Deposit date:2019-01-18
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural insights into nanoRNA degradation by human Rexo2.
Rna, 25, 2019
1J54
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BU of 1j54 by Molmil
Structure of the N-terminal exonuclease domain of the epsilon subunit of E.coli DNA polymerase III at pH 5.8
Descriptor: 1,2-ETHANEDIOL, DNA polymerase III, epsilon chain, ...
Authors:Hamdan, S, Carr, P.D, Brown, S.E, Ollis, D.L, Dixon, N.E.
Deposit date:2002-01-22
Release date:2002-10-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
Structure, 10, 2002
5DK5
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BU of 5dk5 by Molmil
Crystal structure of CRN-4-MES complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cell death-related nuclease 4, ISOPROPYL ALCOHOL, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2015-09-03
Release date:2016-08-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)
J.Med.Chem., 59, 2016

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