PDB: 86 件ウェブページステータス検索Chemie searchBIRD

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7Z5C	Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R. 登録日 2022-03-09 公開日 2022-05-11 実験手法 ELECTRON MICROSCOPY (4.16 Å) 主引用文献 FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
4UQI	AP2 controls clathrin polymerization with a membrane-activated switch 分子名称: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ... 著者 Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J. 登録日 2014-06-23 公開日 2014-07-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch. Science, 345, 2014
8T1O	AP2 bound to MSP2N2 nanodisc with Tgn38 cargo peptide; composite map 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Baker, R.W, Cannon, K.S, Reta, S. 登録日 2023-06-02 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins. J.Struct.Biol., 215, 2023
1W63	AP1 clathrin adaptor core 分子名称: ADAPTER-RELATED PROTEIN COMPLEX 1 BETA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 SIGMA 1A SUBUNIT, ... 著者 Heldwein, E, Macia, E, Wang, J, Yin, H.L, Kirchhausen, T, Harrison, S.C. 登録日 2004-08-12 公開日 2004-09-21 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Crystal Structure of the Clathrin Adaptor Protein 1 Core Proc.Natl.Acad.Sci.USA, 101, 2004
2BP5	MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG 分子名称: CLATHRIN COAT ASSEMBLY PROTEIN AP50, P2X PURINOCEPTOR 4 著者 Royle, S.J, Evans, P.R, Owen, D.J, Murrell-Lagnado, R.D. 登録日 2005-04-18 公開日 2005-07-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Non-Canonical Yxxg-Phi Endocytic Motifs: Recognition by Ap2 and Preferential Utilization in P2X4 Receptors. J.Cell.Sci, 118, 2005
2VGL	AP2 CLATHRIN ADAPTOR CORE 分子名称: ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ... 著者 Owen, D.J, Collins, B.M, McCoy, A.J, Evans, P.R. 登録日 2007-11-14 公開日 2007-12-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular Architecture and Functional Model of the Endocytic Ap2 Complex Cell(Cambridge,Mass.), 109, 2002
2XA7	AP2 clathrin adaptor core in active complex with cargo peptides 分子名称: ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ... 著者 Jackson, L.P, Kelly, B.T, McCoy, A.J, Evans, P.R, Owen, D.J. 登録日 2010-03-29 公開日 2010-07-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex Cell(Cambridge,Mass.), 141, 2010
2JKT	AP2 CLATHRIN ADAPTOR CORE with CD4 Dileucine peptide RM(phosphoS) EIKRLLSE Q to E mutant 分子名称: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ... 著者 Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R. 登録日 2008-08-29 公開日 2008-10-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex. Nature, 456, 2008
2JKR	AP2 CLATHRIN ADAPTOR CORE with Dileucine peptide RM(phosphoS)QIKRLLSE 分子名称: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ... 著者 Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R. 登録日 2008-08-29 公開日 2008-10-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex. Nature, 456, 2008
6YAF	AP2 on a membrane containing tyrosine-based cargo peptide 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. 登録日 2020-03-12 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (9.1 Å) 主引用文献 Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
6YAE	AP2 core in physiological buffer 分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Kane Dickson, V, Kovtun, O, Kelly, B.T, Owen, D.J, Briggs, J.A.G. 登録日 2020-03-12 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
6YAH	AP2 in clathrin coats assembled on a membrane containing dileucine- and tyrosine-based cargo peptides 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. 登録日 2020-03-12 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (10.2 Å) 主引用文献 Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
6OXL	CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 (mu E302K) BOUND TO NECAP IN THE PRESENCE OF SS DNA 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J, Leschziner, A.E, Hollopeter, G. 登録日 2019-05-13 公開日 2019-09-11 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. Elife, 8, 2019
5FPI	Mu2 adaptin subunit of the AP2 adaptor (C-terminal domain) complexed with Integrin alpha4 internalisation peptide QYKSILQE 分子名称: AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT 著者 Owen, D.J, Evans, P.R, Ivaska, J. 登録日 2015-11-30 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions Nat.Struct.Mol.Biol., 23, 2016
6OWO	CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 CORE BOUND TO NECAP 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J.S, Leschziner, A.E, Hollopeter, G. 登録日 2019-05-10 公開日 2019-09-11 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. Elife, 8, 2019
6QH5	AP2 clathrin adaptor mu2T156-phosphorylated core in closed conformation 分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. 登録日 2019-01-15 公開日 2019-09-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
6QH6	AP2 clathrin adaptor core with two cargo peptides in open+ conformation 分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. 登録日 2019-01-15 公開日 2019-09-04 最終更新日 2022-12-07 実験手法 X-RAY DIFFRACTION (5 Å) 主引用文献 Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
6QH7	AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation 分子名称: ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ... 著者 Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. 登録日 2019-01-15 公開日 2019-09-04 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
7RWA	AP2 bound to heparin and Tgn38 tyrosine cargo peptide 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Baker, R.W, Hollopeter, G, Partlow, E.A. 登録日 2021-08-19 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
7RW9	AP2 bound to heparin in the bowl conformation 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Baker, R.W, Hollopeter, G, Partlow, E.A. 登録日 2021-08-19 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
7RWC	AP2 bound to the APA domain of SGIP and heparin; partial signal subtraction and symmetry expansion 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Baker, R.W, Hollopeter, G, Partlow, E.A. 登録日 2021-08-19 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
7RWB	AP2 bound to the APA domain of SGIP in the presence of heparin 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Baker, R.W, Hollopeter, G, Partlow, E.A. 登録日 2021-08-19 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
7RW8	AP2 bound to heparin in the closed conformation 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Baker, R.W, Hollopeter, G, Partlow, E.A. 登録日 2021-08-19 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
7OHO	Crystal structure of AP2 FCHO2 chimera 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ... 著者 Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. 登録日 2021-05-11 公開日 2022-06-01 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
7OG1	AP2 clathrin adaptor core in complex with cargo peptide and FCHO2 分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... 著者 Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. 登録日 2021-05-05 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022

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