PDB: 336 件ウェブページステータス検索Chemie searchBIRD

---

1ZZ0	Crystal structure of a HDAC-like protein with acetate bound 分子名称: ACETATE ION, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... 著者 Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. 登録日 2005-06-13 公開日 2005-11-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
1ZZ3	Crystal structure of a HDAC-like protein with CypX bound 分子名称: 3-CYCLOPENTYL-N-HYDROXYPROPANAMIDE, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... 著者 Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. 登録日 2005-06-13 公開日 2005-11-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
1ZZ1	Crystal structure of a HDAC-like protein with SAHA bound 分子名称: Histone deacetylase-like amidohydrolase, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, POTASSIUM ION, ... 著者 Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. 登録日 2005-06-13 公開日 2005-11-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
5WGM	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with ACY-1083 分子名称: 1,2-ETHANEDIOL, 2-[(4,4-difluoro-1-phenylcyclohexyl)amino]-N-hydroxypyrimidine-5-carboxamide, DI(HYDROXYETHYL)ETHER, ... 著者 Porter, N.J, Christianson, D.W. 登録日 2017-07-14 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WGK	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HPB 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Hdac6 protein, ... 著者 Porter, N.J, Christianson, D.W. 登録日 2017-07-14 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.822 Å) 主引用文献 Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WGL	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with ricolinostat (ACY-1215) 分子名称: 1,2-ETHANEDIOL, 2-(diphenylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]pyrimidine-5-carboxamide, CITRATE ANION, ... 著者 Porter, N.J, Christianson, D.W. 登録日 2017-07-14 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5ZOO	Crystal structure of histone deacetylase 4 (HDAC4) in complex with a SMRT corepressor SP1 fragment 分子名称: Histone deacetylase 4, POTASSIUM ION, SMRT corepressor SP1 fragment, ... 著者 Park, S.Y, Hwang, H.J, Kim, J.S. 登録日 2018-04-13 公開日 2018-11-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4. Nucleic Acids Res., 46, 2018
5ZOP	Crystal structure of histone deacetylase 4 (HDAC4) in complex with a SMRT corepressor SP2 fragment 分子名称: Histone deacetylase 4, POTASSIUM ION, SMRT corepressor SP2 fragment, ... 著者 Park, S.Y, Hwang, H.J, Kim, J.S. 登録日 2018-04-13 公開日 2018-10-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.698 Å) 主引用文献 Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4. Nucleic Acids Res., 46, 2018
5ZMP	The structure of a lysine deacylase 分子名称: ZINC ION, lysine deacylase 著者 Ge, F. 登録日 2018-04-05 公開日 2019-02-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 The structure of a lysine deacylase To Be Published
3MAX	Crystal Structure of Human HDAC2 complexed with an N-(2-aminophenyl)benzamide 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Histone deacetylase 2, ... 著者 Skene, R.J, Jennings, A.J. 登録日 2010-03-24 公開日 2010-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides. Bioorg.Med.Chem.Lett., 20, 2010
3MEN	Crystal structure of acetylpolyamine aminohydrolase from Burkholderia pseudomallei, iodide soak 分子名称: Acetylpolyamine aminohydrolase, IODIDE ION, POTASSIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-03-31 公開日 2010-04-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics, 12, 2011
3MZ6	Crystal structure of D101L Fe2+ HDAC8 complexed with M344 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, FE (II) ION, Histone deacetylase 8, ... 著者 Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. 登録日 2010-05-11 公開日 2010-06-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
3MZ7	Crystal structure of D101L Co2+ HDAC8 complexed with M344 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, COBALT (II) ION, GLYCEROL, ... 著者 Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. 登録日 2010-05-11 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
3MZ3	Crystal structure of Co2+ HDAC8 complexed with M344 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, COBALT (II) ION, Histone deacetylase 8, ... 著者 Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. 登録日 2010-05-11 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
3MZ4	Crystal structure of D101L Mn2+ HDAC8 complexed with M344 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, Histone deacetylase 8, ... 著者 Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. 登録日 2010-05-11 公開日 2010-06-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.845 Å) 主引用文献 Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
7UK2	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with NN-390 分子名称: Hdac6 protein, N-hydroxy-4-{[(propan-2-yl)(2,3,4,5-tetrafluorobenzene-1-sulfonyl)amino]methyl}benzamide, POTASSIUM ION, ... 著者 Erdogan, F, Seo, H.-S, Dhe-Paganon, S. 登録日 2022-03-31 公開日 2022-11-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma. Pharmaceuticals, 15, 2022
3Q9E	Crystal structure of H159A APAH complexed with acetylspermine 分子名称: Acetylpolyamine amidohydrolase, N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamide, POTASSIUM ION, ... 著者 Lombardi, P.M, Christianson, D.W. 登録日 2011-01-07 公開日 2011-03-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases . Biochemistry, 50, 2011
3Q9F	Crystal Structure of APAH complexed with CAPS 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Acetylpolyamine amidohydrolase, PHOSPHATE ION, ... 著者 Lombardi, P.M, Christianson, D.W. 登録日 2011-01-07 公開日 2011-03-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases . Biochemistry, 50, 2011
3Q9B	Crystal Structure of APAH complexed with M344 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Acetylpolyamine amidohydrolase, DIMETHYL SULFOXIDE, ... 著者 Lombardi, P.M, Christianson, D.W. 登録日 2011-01-07 公開日 2011-03-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases . Biochemistry, 50, 2011
7WJL	Crystal structure of S. cerevisiae Hos3 分子名称: ACETATE ION, Histone deacetylase HOS3, ZINC ION 著者 Pang, N.N, Che, S.Y, Yang, N. 登録日 2022-01-07 公開日 2023-01-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural characterization of fungus-specific histone deacetylase Hos3 provides insights into developing selective inhibitors with antifungal activity. J.Biol.Chem., 298, 2022
3EWF	Crystal Structure Analysis of human HDAC8 H143A variant complexed with substrate. 分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, Histone deacetylase 8, PEPTIDIC SUBSTRATE, ... 著者 Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. 登録日 2008-10-14 公開日 2008-12-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
3F06	Crystal Structure Analysis of Human HDAC8 D101A Variant. 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, Histone deacetylase 8, ... 著者 Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. 登録日 2008-10-24 公開日 2008-12-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
3EZT	Crystal Structure Analysis of Human HDAC8 D101E Variant 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, Histone deacetylase 8, ... 著者 Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. 登録日 2008-10-23 公開日 2008-12-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
3F07	Crystal Structure Analysis of Human HDAC8 complexed with APHA in a new monoclinic crystal form 分子名称: (2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide, Histone deacetylase 8, POTASSIUM ION, ... 著者 Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. 登録日 2008-10-24 公開日 2008-12-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
3Q9C	Crystal Structure of H159A APAH complexed with N8-acetylspermidine 分子名称: Acetylpolyamine amidohydrolase, N-{4-[(3-aminopropyl)amino]butyl}acetamide, POTASSIUM ION, ... 著者 Lombardi, P.M, Christianson, D.W. 登録日 2011-01-07 公開日 2011-03-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases . Biochemistry, 50, 2011

<1234567891011121314>