2H1V
| Crystal structure of the Lys87Ala mutant variant of Bacillus subtilis ferrochelatase | 分子名称: | Ferrochelatase, MAGNESIUM ION | 著者 | Hansson, M.D, Karlberg, T, Arys Rahardja, M, Al-Karadaghi, S, Hansson, M. | 登録日 | 2006-05-17 | 公開日 | 2007-01-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Amino Acid Residues His183 and Glu264 in Bacillus subtilis Ferrochelatase Direct and Facilitate the Insertion of Metal Ion into Protoporphyrin IX Biochemistry, 46, 2007
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8AT8
| Structure of coproporphyrin III-LmCpfC | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | 著者 | Gabler, T, Hofbauer, S. | 登録日 | 2022-08-22 | 公開日 | 2022-12-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation. Protein Sci., 32, 2023
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3HCN
| Hg and protoporphyrin bound Human Ferrochelatase | 分子名称: | BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | 登録日 | 2009-05-06 | 公開日 | 2009-11-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Product release rather than chelation determines metal specificity for ferrochelatase. J.Mol.Biol., 393, 2009
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3GOQ
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6RWV
| Structure of apo-LmCpfC | 分子名称: | Ferrochelatase, GLYCEROL, PHOSPHATE ION, ... | 著者 | Hofbauer, S, Helm, J, Djinovic-Carugo, K, Furtmueller, P.G. | 登録日 | 2019-06-06 | 公開日 | 2019-12-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6386379 Å) | 主引用文献 | Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase. Febs J., 287, 2020
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6SV3
| Structure of coproheme-LmCpfC | 分子名称: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Ferrochelatase, GLYCEROL | 著者 | Hofbauer, S, Helm, J, Djinovic-Carugo, K, Furtmueller, P.G. | 登録日 | 2019-09-17 | 公開日 | 2019-12-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.64000869 Å) | 主引用文献 | Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase. Febs J., 287, 2020
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2HRC
| 1.7 angstrom structure of human ferrochelatase variant R115L | 分子名称: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Medlock, A, Swartz, L, Dailey, T.A, Dailey, H.A, Lanzilotta, W.N. | 登録日 | 2006-07-20 | 公開日 | 2007-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Substrate interactions with human ferrochelatase Proc.Natl.Acad.Sci.Usa, 104, 2007
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3AQI
| H240A variant of human ferrochelatase | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | 著者 | Lanzilotta, W.N, Medlock, A.E, Dailey, T.A, Dailey, H.A. | 登録日 | 2010-11-03 | 公開日 | 2012-01-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | H240A variant of human ferrochelatase To be published
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2HK6
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1DOZ
| CRYSTAL STRUCTURE OF FERROCHELATASE | 分子名称: | FERROCHELATASE, MAGNESIUM ION | 著者 | Lecerof, D, Fodje, M, Hansson, A, Hansson, M, Al-Karadaghi, S. | 登録日 | 1999-12-22 | 公開日 | 2000-01-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and mechanistic basis of porphyrin metallation by ferrochelatase. J.Mol.Biol., 297, 2000
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3HCO
| Human ferrochelatase with Cd and protoporphyrin IX bound | 分子名称: | BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | 登録日 | 2009-05-06 | 公開日 | 2009-11-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Product release rather than chelation determines metal specificity for ferrochelatase. J.Mol.Biol., 393, 2009
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2Q2N
| Crystal structure of Bacillus subtilis ferrochelatase in complex with deuteroporphyrin IX 2,4-disulfonic acid dihydrochloride | 分子名称: | Ferrochelatase, MAGNESIUM ION, PROTOPORPHYRIN IX 2,4-DISULFONIC ACID | 著者 | Karlberg, T, Thorvaldsen, O.H, Al-Karadaghi, S. | 登録日 | 2007-05-29 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Porphyrin binding and distortion and substrate specificity in the ferrochelatase reaction: the role of active site residues J.Mol.Biol., 378, 2008
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4F4D
| F337R variant of human ferrochelatase | 分子名称: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Lanzilotta, W.N, Medlock, A.E, Dailey, T.E, Dailey, H.A. | 登録日 | 2012-05-10 | 公開日 | 2012-09-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | F337R Variant of Human Ferrochelatase TO BE PUBLISHED
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1AK1
| FERROCHELATASE FROM BACILLUS SUBTILIS | 分子名称: | FERROCHELATASE | 著者 | Al-Karadaghi, S, Hansson, M, Nikonov, S, Jonsson, B, Hederstedt, L. | 登録日 | 1997-05-28 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of ferrochelatase: the terminal enzyme in heme biosynthesis. Structure, 5, 1997
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1C1H
| CRYSTAL STRUCTURE OF BACILLUS SUBTILIS FERROCHELATASE IN COMPLEX WITH N-METHYL MESOPORPHYRIN | 分子名称: | FERROCHELATASE, MAGNESIUM ION, N-METHYLMESOPORPHYRIN | 著者 | Lecerof, D, Fodje, M, Hansson, A, Hansson, M, Al-Karadaghi, S. | 登録日 | 1999-07-22 | 公開日 | 2000-03-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and mechanistic basis of porphyrin metallation by ferrochelatase. J.Mol.Biol., 297, 2000
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3M4Z
| Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site | 分子名称: | CHLORIDE ION, COBALT (II) ION, Ferrochelatase, ... | 著者 | Soderberg, C.A.G, Hansson, M.D, Sreekanth, R, Al-Karadaghi, S, Hansson, M. | 登録日 | 2010-03-12 | 公開日 | 2010-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Bacterial ferrochelatase goes human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase To be Published
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3HCP
| Human ferrochelatase with Mn and deuteroporphyrin bound | 分子名称: | CHOLIC ACID, FE(III) DEUTEROPORPHYRIN IX, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | 登録日 | 2009-05-06 | 公開日 | 2009-11-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Product release rather than chelation determines metal specificity for ferrochelatase. J.Mol.Biol., 393, 2009
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7CT7
| FECH - inhibitor complex 2 | 分子名称: | 2-[[(4-chlorophenyl)amino]methyl]-5-propyl-6H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | 著者 | Lee, S.J, Park, J. | 登録日 | 2020-08-18 | 公開日 | 2021-08-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | FECH - inhibitor complex 1 to be published
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7CTC
| FECH - inhibitor complex 1 | 分子名称: | 2-(4-tert-butylphenyl)-5-[(quinolin-2-ylamino)methyl]-6H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | 著者 | Lee, S.J, Park, J. | 登録日 | 2020-08-18 | 公開日 | 2021-08-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | FECH - inhibitor complex 1 to be published
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2QD4
| Wild type human ferrochelatase crystallized with MnCl2 | 分子名称: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | 登録日 | 2007-06-20 | 公開日 | 2007-10-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
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1HRK
| CRYSTAL STRUCTURE OF HUMAN FERROCHELATASE | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, FERROCHELATASE | 著者 | Wu, C.K, Dailey, H.A, Rose, J.P, Burden, A, Sellers, V.M, Wang, B.-C. | 登録日 | 2000-12-21 | 公開日 | 2001-06-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis. Nat.Struct.Biol., 8, 2001
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1N0I
| Crystal Structure of Ferrochelatase with Cadmium bound at active site | 分子名称: | CADMIUM ION, CHLORIDE ION, Ferrochelatase, ... | 著者 | Lecerof, D, Fodje, M.N, Leon, R.A, Olsson, U, Hansson, A, Sigfridsson, E, Ryde, U, Hansson, M, Al-Karadaghi, S. | 登録日 | 2002-10-14 | 公開日 | 2003-05-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Metal binding to Bacillus subtilis ferrochelatase and interaction between metal sites J.Biol.Inorg.Chem., 8, 2003
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3W1W
| Protein-drug complex | 分子名称: | 1,2-ETHANEDIOL, 2-HYDROXYBENZOIC ACID, CHOLIC ACID, ... | 著者 | Ishii, R, Gupta, V, Yamaguchi, Y, Handa, H, Nureki, O. | 登録日 | 2012-11-21 | 公開日 | 2013-10-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | 主引用文献 | Salicylic Acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity Mol.Pharmacol., 84, 2013
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2AC4
| Crystal structure of the His183Cys mutant variant of Bacillus subtilis Ferrochelatase | 分子名称: | Ferrochelatase | 著者 | Shipovskov, S, Karlberg, T, Fodje, M, Hansson, M.D, Ferreira, G.C, Hansson, M, Reimann, C.T, Al-Karadaghi, S. | 登録日 | 2005-07-18 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism. J.Mol.Biol., 352, 2005
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8OFL
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