PDB: 182 件ウェブページステータス検索Chemie searchBIRD

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3VKX	Structure of PCNA 分子名称: 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... 著者 Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. 登録日 2011-11-26 公開日 2012-03-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication J.Biol.Chem., 287, 2012
6HVO	Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta 分子名称: DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION 著者 Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A. 登録日 2018-10-11 公開日 2019-01-23 最終更新日 2019-03-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA). J.Biol.Chem., 294, 2019
3WGW	Structure of PCNA bound to a small molecule inhibitor 分子名称: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION 著者 Hashimoto, H. 登録日 2013-08-12 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
3F1W	Crystal structure of a mutant proliferating cell nuclear antigen that blocks translesion synthesis 分子名称: Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Ramaswamy, S, Washington, M.T. 登録日 2008-10-28 公開日 2008-12-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis. Biochemistry, 47, 2008
5MLO	Crystal structure of human PCNA in complex with ZRANB3 PIP box peptide 分子名称: Proliferating cell nuclear antigen, SODIUM ION, ZRANB3 PIP box peptide 著者 Ariza, A. 登録日 2016-12-07 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017
5MLW	Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide 分子名称: APIM motif peptide, Proliferating cell nuclear antigen, SULFATE ION 著者 Ariza, A. 登録日 2016-12-07 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017
5MAV	Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide. 分子名称: Poly (ADP-ribose) glycohydrolase, Proliferating cell nuclear antigen 著者 Grishkovskaya, I, Djinovic-Carugo, K, Slade, D. 登録日 2016-11-06 公開日 2017-08-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.575 Å) 主引用文献 A novel non-canonical PIP-box mediates PARG interaction with PCNA. Nucleic Acids Res., 45, 2017
6J0J	Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani with an unexplained density near residues Pro229,Pr0267 and Ala285 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proliferating cell nuclear antigen 著者 Iqbal, N, Sharma, S, Singh, T.P. 登録日 2018-12-24 公開日 2019-01-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani with an unexplained density near residues Pro229,Pr0267 and Ala285 To Be Published
3FDS	Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase IV, ... 著者 Ling, H. 登録日 2008-11-26 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Mol.Microbiol., 71, 2009
5MOM	Crystal Structure of PCNA encoding the hypomorphic mutation S228I 分子名称: Proliferating cell nuclear antigen 著者 Biasutto, A.J, Mancini, E.J, Green, C.M, Wilson, R.H.C. 登録日 2016-12-14 公開日 2017-01-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair (Amst.), 50, 2017
6K2M	Crystal structure of the complex of Proliferating Cell Nuclear Antigen from Leishmania donovani with arginine at 3.19 A resolution. 分子名称: ARGININE, Proliferating cell nuclear antigen 著者 Viswanathan, V, Iqbal, N, Sharma, S, Singh, T.P. 登録日 2019-05-15 公開日 2019-05-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Crystal structure of the complex of Proliferating Cell Nuclear Antigen from Leishmania donovani with arginine at 3.19 A resolution. To Be Published
3GPM	Structure of the trimeric form of the E113G PCNA mutant protein 分子名称: Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-03-23 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions. Acta Crystallogr.,Sect.D, 65, 2009
3GPN	Structure of the non-trimeric form of the E113G PCNA mutant protein 分子名称: Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-03-23 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions. Acta Crystallogr.,Sect.D, 65, 2009
3HI8	Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii 分子名称: Proliferating cell nuclear antigen PcnA 著者 Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R. 登録日 2009-05-19 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.202 Å) 主引用文献 Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment. Acta Crystallogr.,Sect.D, 65, 2009
6QC0	PCNA complex with Cdt2 C-terminal PIP-box peptide 分子名称: Denticleless protein homolog, Proliferating cell nuclear antigen 著者 Perrakis, A.P, von Castelmur, E. 登録日 2018-12-25 公開日 2019-01-23 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1. Life Sci Alliance, 1, 2018
6QCG	PCNA complex with Cdt1 N-terminal PIP-box peptide 分子名称: DNA replication factor Cdt1, Proliferating cell nuclear antigen 著者 Perrakis, A, von Castelmur, E. 登録日 2018-12-28 公開日 2019-01-23 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1. Life Sci Alliance, 1, 2018
6QH1	The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide 分子名称: Proliferating cell nuclear antigen, S-phase delaying protein 1 著者 Kragelund, B.B, Nielsen, O, Olsen, J.G, Kassem, N, Prestel, A. 登録日 2019-01-14 公開日 2020-02-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide To Be Published
6T7Y	Structure of PCNA bound to cPIP motif of DP2 from P. abyssi 分子名称: DNA polymerase sliding clamp, cPIP motif from the DP2 large subunit of PolD 著者 Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L. 登録日 2019-10-23 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA. Nat Commun, 11, 2020
6T7X	Crystal structure of PCNA from P. abyssi 分子名称: DNA polymerase sliding clamp 著者 Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L. 登録日 2019-10-23 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA. Nat Commun, 11, 2020
6W9W	R80A PCNA mutant defective in BIR 分子名称: Proliferating cell nuclear antigen 著者 Ripley, B.M, Washington, M.T. 登録日 2020-03-23 公開日 2020-09-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A To be Published
2HIK	heterotrimeric PCNA sliding clamp 分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405) 著者 Pascal, J.M, Tsodikov, O.V, Ellenberger, T. 登録日 2006-06-29 公開日 2006-11-07 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA. Mol.Cell, 24, 2006
2HII	heterotrimeric PCNA sliding clamp 分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405) 著者 Pascal, J.M, Tsodikov, O.V, Ellenberger, T. 登録日 2006-06-29 公開日 2006-11-07 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA. Mol.Cell, 24, 2006
3IFV	Crystal structure of the Haloferax volcanii proliferating cell nuclear antigen 分子名称: PCNA, SODIUM ION 著者 Winter, J.A, Christofi, P, Morroll, S, Bunting, K.A. 登録日 2009-07-26 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation Bmc Struct.Biol., 9, 2009
2IO4	Crystal structure of PCNA12 dimer from Sulfolobus solfataricus. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA polymerase sliding clamp B, ... 著者 Hlinkova, V, Ling, H. 登録日 2006-10-09 公開日 2008-04-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. Acta Crystallogr.,Sect.D, 64, 2008
3JA9	Structure of native human PCNA 分子名称: Proliferating cell nuclear antigen 著者 Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y. 登録日 2015-05-19 公開日 2015-12-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (22 Å) 主引用文献 Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA Sci Rep, 5, 2015

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