6DAO
| NahE WT selenomethionine | 分子名称: | Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase | 著者 | Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P. | 登録日 | 2018-05-01 | 公開日 | 2019-05-08 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (1.939 Å) | 主引用文献 | Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily. Biochemistry, 57, 2018
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1XKY
| Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis at 1.94A Resolution. | 分子名称: | POTASSIUM ION, dihydrodipicolinate synthase | 著者 | Levdikov, V, Blagova, E, Fogg, M.J, Brannigan, J.A, Milioti, N, Wilkinson, A.J, Wilson, K.S. | 登録日 | 2004-09-30 | 公開日 | 2005-10-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution Proteins, 62, 2006
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7KXH
| Dihydrodipicolinate synthase (DHDPS) from C.jejuni with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site in C2221 space group | 分子名称: | (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... | 著者 | Saran, S, Sanders, D.A.R. | 登録日 | 2020-12-03 | 公開日 | 2021-12-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | B-FACTOR ANALYSIS SUGGEST THAT L-LYSINE AND R, R-BISLYSINE ALLOSTERICALLY INHIBIT Cj.DHDPS ENZYME BY DECREASING PROTEIN DYNAMICS. To Be Published
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2A6N
| Dihydrodipicolinate synthase (E. coli)- mutant R138A | 分子名称: | Dihydrodipicolinate synthase, POTASSIUM ION | 著者 | Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. | 登録日 | 2005-07-03 | 公開日 | 2005-10-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase. Biochemistry, 44, 2005
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3UQN
| Crystal structure of dihydrodipicolinate synthase from Acinetobacter baumannii complexed with Oxamic acid at 1.9 Angstrom resolution | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, OXAMIC ACID | 著者 | Singh, A, Kaushik, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2011-11-21 | 公開日 | 2011-12-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of dihydrodipicolinate synthase from Acinetobacter baumannii complexed with Oxamic acid at 1.9 Angstrom resolution To be Published
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1F73
| CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM III IN COMPLEX WITH SIALIC ACID ALDITOL | 分子名称: | 2,4,6,7,8,9-HEXAHYDROXY-5-METHYLCARBOXAMIDO NONANOIC ACID, GLYCEROL, N-ACETYL NEURAMINATE LYASE | 著者 | Barbosa, J.A.R.G, Smith, B.J, DeGori, R, Lawrence, M.C. | 登録日 | 2000-06-25 | 公開日 | 2000-11-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme. J.Mol.Biol., 303, 2000
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7KG5
| Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56W mutant with pyruvate bound in the active site | 分子名称: | 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ... | 著者 | Saran, S, Majdi Yazdi, M, Sanders, D.A.R. | 登録日 | 2020-10-15 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Fluorescence-based Assay Development for Screening Novel Inhibitors of Dihydrodipicolinate Synthase from Campylobacter jejuni To Be Published
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2VC6
| Structure of MosA from S. meliloti with pyruvate bound | 分子名称: | DIHYDRODIPICOLINATE SYNTHASE | 著者 | Phenix, C.P, Nienaber, K.H, Tam, P.H, Delbaere, L.T.J, Palmer, D.R.J. | 登録日 | 2007-09-18 | 公開日 | 2008-06-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural, functional and calorimetric investigation of MosA, a dihydrodipicolinate synthase from Sinorhizobium meliloti l5-30, does not support involvement in rhizopine biosynthesis. Chembiochem, 9, 2008
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4AHQ
| Crystal Structure of N-acetylneuraminic acid lyase mutant K165C from Staphylococcus aureus | 分子名称: | N-ACETYLNEURAMINATE LYASE | 著者 | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A. | 登録日 | 2012-02-06 | 公開日 | 2013-01-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy. Chembiochem, 14, 2013
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4WOZ
| Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine | 分子名称: | 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, N-acetylneuraminate lyase | 著者 | Liu, W.D, Guo, R.T, Cui, Y.F, Chen, X, Wu, Q.Q, Zhu, D.M. | 登録日 | 2014-10-17 | 公開日 | 2015-10-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine to be published
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6RAB
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7KLT
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3S5O
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3LCX
| L-KDO aldolase | 分子名称: | N-acetylneuraminate lyase, SULFATE ION | 著者 | Chou, C.-Y, Huang, K.-F, Wang, A.H.-J, Ko, T.-P. | 登録日 | 2010-01-12 | 公開日 | 2011-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251 To be Published
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4OE7
| Crystal structure of YagE, a KDG aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal | 分子名称: | (4R)-4-hydroxy-2,5-dioxopentanoic acid, (4S)-4-hydroxy-2,5-dioxopentanoic acid, 1,2-ETHANEDIOL, ... | 著者 | Manoj Kumar, P, Baskar, V, Manicka, S, Krishnaswamy, S. | 登録日 | 2014-01-12 | 公開日 | 2014-12-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal structure of YagE, a KDG aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal To be Published
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4PTN
| Crystal Structure of YagE, a KDG aldolase protein in complex with Magnesium cation coordinated L-glyceraldehyde | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, L-glyceraldehyde, ... | 著者 | Manoj Kumar, P, Baskar, V, Manicka, S, Krishnaswamy, S. | 登録日 | 2014-03-11 | 公開日 | 2014-12-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal structure of YagE, a putative DHDPS-like protein from Escherichia coli K12. Proteins, 71, 2008
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7LBD
| Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site in C2221 space group | 分子名称: | 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ... | 著者 | Saran, S, Yazdi, M.M, Sanders, D.A.R. | 登録日 | 2021-01-07 | 公開日 | 2022-01-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Reversing the roles of a crucial hydrogen-bonding pair: a lysine-insensitive mutant of Campylobacter jejuni dihydrodipicolinate synthase, H59K, binds histidine in its allosteric site To Be Published
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3TDF
| Crystal structure of the complex of Dihydrodipicolinate synthase from Acinetobacter baumannii with 2-Ketobutanoic acid at 1.99 A resolution | 分子名称: | 2-KETOBUTYRIC ACID, Dihydrodipicolinate synthase | 著者 | Kumar, M, Kaushik, S, Sinha, M, Kaur, P, Tewari, R, Sharma, S, Singh, T.P. | 登録日 | 2011-08-11 | 公開日 | 2011-08-31 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal structure of the complex of Dihydrodipicolinate synthase from Acinetobacter baumannii with 2-Ketobutanoic acid at 1.99 A resolution To be Published
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5T25
| Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. | 分子名称: | 4-hydroxy-tetrahydrodipicolinate synthase, LYSINE, SODIUM ION | 著者 | Chooback, L, Thomas, L.M, Karsten, W.E, Fleming, C.D, Seabourn, P. | 登録日 | 2016-08-23 | 公開日 | 2017-03-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.991 Å) | 主引用文献 | Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. To Be Published
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3DU0
| E. coli dihydrodipicolinate synthase with first substrate, pyruvate, bound in active site | 分子名称: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | 著者 | Dobson, R.C.J, Devenish, S.R.A, Gerrard, J.A, Jameson, G.B. | 登録日 | 2008-07-16 | 公開日 | 2008-11-18 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate. Acta Crystallogr.,Sect.F, 64, 2008
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1W37
| 2-keto-3-deoxygluconate(KDG) aldolase of Sulfolobus solfataricus | 分子名称: | 2-KETO-3-DEOXY GLUCONATE ALDOLASE, GLYCEROL, SODIUM ION | 著者 | Theodossis, A, Walden, H, Westwick, E.J, Connaris, H, Lamble, H.J, Hough, D.W, Danson, M.J, Taylor, G.L. | 登録日 | 2004-07-13 | 公開日 | 2004-09-02 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus. J. Biol. Chem., 279, 2004
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6GSO
| Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y132V,T157C variant | 分子名称: | 1,2-ETHANEDIOL, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase, GLYCEROL | 著者 | Crennell, S.J, Danson, M.J, Royer, S. | 登録日 | 2018-06-15 | 公開日 | 2019-06-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y132V,T157C variant To Be Published
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7JZE
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6DAQ
| PhdJ bound to substrate intermediate | 分子名称: | PhdJ | 著者 | Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P. | 登録日 | 2018-05-01 | 公開日 | 2019-04-10 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily. Biochemistry, 57, 2018
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4DPP
| The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana | 分子名称: | Dihydrodipicolinate synthase 2, chloroplastic, SODIUM ION | 著者 | Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G. | 登録日 | 2012-02-14 | 公開日 | 2012-07-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana Plos One, 7, 2012
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