5AW3
 
 | | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 100 min | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Ogawa, H, Cornelius, F, Hirata, A, Toyoshima, C. | | 登録日 | 2015-07-01 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography.
Nat Commun, 6, 2015
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5AVU
 | | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 7.0 min | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Ogawa, H, Cornelius, F, Hirata, A, Toyoshima, C. | | 登録日 | 2015-07-01 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography.
Nat Commun, 6, 2015
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5AW2
 | | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 85 min | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Ogawa, H, Cornelius, F, Hirata, A, Toyoshima, C. | | 登録日 | 2015-07-01 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography.
Nat Commun, 6, 2015
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5AVR
 | | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 1.5 min | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Ogawa, H, Cornelius, F, Hirata, A, Toyoshima, C. | | 登録日 | 2015-07-01 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography.
Nat Commun, 6, 2015
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5AVZ
 | | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 55 min | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Ogawa, H, Cornelius, F, Hirata, A, Toyoshima, C. | | 登録日 | 2015-07-01 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography.
Nat Commun, 6, 2015
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5AVW
 | | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 16.5 min | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Ogawa, H, Cornelius, F, Hirata, A, Toyoshima, C. | | 登録日 | 2015-07-01 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography.
Nat Commun, 6, 2015
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5AW8
 | | Kinetics by X-ray crystallography: E2.MgF42-.2RB+ crystal | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Ogawa, H, Cornelius, F, Hirata, A, Toyoshima, C. | | 登録日 | 2015-07-01 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography.
Nat Commun, 6, 2015
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7W49
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7W48
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7W47
 | | Crystal structure of the gastric proton pump complexed with tegoprazan | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Potassium-transporting ATPase alpha chain 1, ... | | 著者 | Abe, K, Tanaka, S, Morita, M, Yamagishi, T. | | 登録日 | 2021-11-26 | | 公開日 | 2022-01-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump.
J.Med.Chem., 65, 2022
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7W4A
 | | Cryo-EM structure of the gastric proton pump complexed with revaprazan | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | | 著者 | Abe, K, Tanaka, S, Morita, M, Yamagishi, T. | | 登録日 | 2021-11-26 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump.
J.Med.Chem., 65, 2022
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7W7T
 | | The E1-BeF3- 2Ca2+ of SERCA2b | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | | 登録日 | 2021-12-06 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle.
Cell Rep, 41, 2022
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7W7V
 | | 'late' E2P of SERCA2b | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | | 登録日 | 2021-12-06 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle.
Cell Rep, 41, 2022
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7W7W
 | | E2 Pi of SERCA2b | | 分子名称: | MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, TETRAFLUOROALUMINATE ION | | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | | 登録日 | 2021-12-06 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle.
Cell Rep, 41, 2022
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7W7U
 | | The 'Ca2+-unbound' BeF3- of SERCA2b | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | | 登録日 | 2021-12-06 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle.
Cell Rep, 41, 2022
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7WZ0
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by inorganic phosphate with ouabain | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYX
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP with istaroxime | | 分子名称: | (3E,5S,8R,9S,10R,13S,14S)-3-(2-azanylethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYV
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP in the presence of 40 mM Mg2+ | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYU
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYW
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by inorganic phosphate | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYZ
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP with ouabain | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYS
 | | Crystal structures of Na+,K+-ATPase in complex with istaroxime | | 分子名称: | (3E,5S,8R,9S,10R,13S,14S)-3-(2-azanylethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.71 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYY
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by inorganic phosphate with istaroxime | | 分子名称: | (3E,5S,8R,9S,10R,13S,14S)-3-(2-azanylethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYT
 | | Crystal structures of Na+,K+-ATPase in complex with ouabain | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7X23
 | | Cryo-EM structure of non gastric H,K-ATPase alpha2 SPWC mutant in 3Na+E1-AMPPCPF state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Potassium-transporting ATPase alpha chain 2, ... | | 著者 | Abe, K, Nakanishi, H, Young, V, Artigas, P. | | 登録日 | 2022-02-25 | | 公開日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure and function of H + /K + pump mutants reveal Na + /K + pump mechanisms.
Nat Commun, 13, 2022
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