PDB: 354 件ウェブページステータス検索Chemie searchBIRD

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6O1V	Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... 著者 Zhang, Z, Liu, F, Chen, J, Levit, A, Shoichet, B. 登録日 2019-02-21 公開日 2019-06-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural identification of a hotspot on CFTR for potentiation. Science, 364, 2019
6O30	Lipid A transporter MsbA from Salmonella typhimurium 分子名称: Lipid A export ATP-binding/permease protein MsbA 著者 Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L. 登録日 2019-02-25 公開日 2019-06-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.47 Å) 主引用文献 Structural Insights into the Lipid A Transport Pathway in MsbA. Structure, 27, 2019
6PAM	Structure of a bacterial Atm1-family ABC transporter with MgADP bound 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6P6J	Structure of YbtPQ importer with substrate Ybt-Fe bound 分子名称: ABC transporter protein, FE (III) ION, inner membrane ABC-transporter, ... 著者 Wang, Z, Hu, W, Zheng, H. 登録日 2019-06-04 公開日 2020-03-04 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter. Sci Adv, 6, 2020
6PAN	Structure of a bacterial Atm1-family ABC exporter with ATP bound 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATM1-type heavy metal exporter 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6PAQ	Structure of a bacterial Atm1-family ABC exporter with ATP bound 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATM1-type heavy metal exporter 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6P6I	Structure of YbtPQ importer 分子名称: ABC transporter protein, inner membrane ABC-transporter 著者 Wang, Z, Hu, W, Zheng, H. 登録日 2019-06-04 公開日 2020-03-04 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter. Sci Adv, 6, 2020
6PAO	Structure of a bacterial Atm1-family ABC exporter with ATP bound 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATM1-type heavy metal exporter 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6PAR	Structure of a bacterial Atm1-family ABC exporter with MgAMPPNP bound 分子名称: ATM1-type heavy metal exporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6PZB	Cryo-EM structure of the pancreatic beta-cell SUR1 Apo state 分子名称: ATP-binding cassette sub-family C member 8 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
6PZI	Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
6PZA	Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.74 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
6Q81	Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state 分子名称: ADENOSINE-5'-DIPHOSPHATE, P-glycoprotein (ABCB1) 著者 Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A. 登録日 2018-12-13 公開日 2018-12-26 最終更新日 2019-04-03 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution. Bmc Struct.Biol., 18, 2018
6PZ9	Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.65 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
8F4B	Bovine multidrug resistance protein 1 (MRP1) bound to cyclic peptide inhibitor 1 (CPI1) 分子名称: Cyclic peptide inhibitor 1 (CPI1), Multidrug resistance-associated protein 1 著者 Pietz, H.L, Chen, J. 登録日 2022-11-10 公開日 2023-03-22 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation. Proc.Natl.Acad.Sci.USA, 120, 2023
8FHK	Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ATP: BmrCD_OC-ATP 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Tang, Q, Mchaourab, H. 登録日 2022-12-14 公開日 2023-11-15 最終更新日 2023-11-22 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nat Commun, 14, 2023
8FWK	CryoEM structure of Human ABCB6 Transporter 分子名称: ATP-binding cassette sub-family B member 6 著者 Shaik, M.M, Myasnikov, A. 登録日 2023-01-22 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 CryoEM structure of Human ABCB6 Transporter To Be Published
8FZQ	Dehosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION 著者 Levring, J, Terry, D.S, Kilic, Z, Fitzgerald, G.A, Blanchard, S.C, Chen, J. 登録日 2023-01-29 公開日 2023-03-29 最終更新日 2023-05-03 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 CFTR function, pathology and pharmacology at single-molecule resolution. Nature, 616, 2023
8FMV	Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-2HT/ATP 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Tang, Q, Mchaourab, H. 登録日 2022-12-24 公開日 2023-11-15 最終更新日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nat Commun, 14, 2023
8FPF	Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ... 著者 Qingyu, T, Hassane, M. 登録日 2023-01-04 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter Nat Commun, 14, 2023
8HF4	Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate closed conformation 分子名称: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transport/processing ATP-binding protein ComA 著者 Yu, L, Xin, X, Min, L. 登録日 2022-11-09 公開日 2023-10-04 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
8HF5	Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate open conformation 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transport/processing ATP-binding protein ComA 著者 Yu, L, Xin, X, Min, L. 登録日 2022-11-09 公開日 2023-10-04 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
8HF6	Cryo-EM structure of nucleotide-bound ComA E647Q mutant 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA 著者 Yu, L, Xin, X, Min, L. 登録日 2022-11-09 公開日 2023-10-04 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
8HF7	Cryo-EM structure of ComA bound to its mature substrate CSP peptide 分子名称: Competence factor transporting ATP-binding protein/permease ComA, Competence-stimulating peptide type 1 著者 Yu, L, Xin, X, Min, L. 登録日 2022-11-09 公開日 2023-10-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
8I4B	Cryo-EM structure of apo-form ABCC4 分子名称: ATP-binding cassette sub-family C member 4 著者 Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. 登録日 2023-01-19 公開日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023

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