7PY3
 
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (the consensus NusA-EC) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | | Deposit date: | 2021-10-08 | | Release date: | 2022-03-23 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
|
|
7F66
 | | eIF2B-SFSV NSs-1-eIF2 | | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | | Authors: | Kashiwagi, K, Ito, T. | | Deposit date: | 2021-06-24 | | Release date: | 2021-12-01 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
|
|
7F67
 | | eIF2B-SFSV NSs-2-eIF2 | | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | | Authors: | Kashiwagi, K, Ito, T. | | Deposit date: | 2021-06-24 | | Release date: | 2021-12-01 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
|
|
7F4G
 | | Structure of RPAP2-bound RNA polymerase II | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-06-18 | | Release date: | 2021-07-07 | | Last modified: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.
Cell Rep, 39, 2022
|
|
7OQY
 | | Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-06-04 | | Release date: | 2021-08-25 | | Last modified: | 2021-11-03 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
|
|
7OQ4
 | | Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-06-02 | | Release date: | 2021-08-25 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
|
|
7OPD
 | | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) | | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-10-06 | | Last modified: | 2021-10-27 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
|
|
7OPC
 | | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) | | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-31 | | Release date: | 2021-10-13 | | Last modified: | 2021-10-27 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
|
|
7OOP
 | | Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | | Descriptor: | DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-28 | | Release date: | 2021-10-06 | | Last modified: | 2021-10-27 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
|
|
7OK0
 | | Cryo-EM structure of the Sulfolobus acidocaldarius RNA polymerase at 2.88 A | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-05-17 | | Release date: | 2021-08-25 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
|
|
7OGM
 | | A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. PNPase-3'ETS(leuZ)-Hfq | | Descriptor: | 3'ETS(LeuZ), Polyribonucleotide nucleotidyltransferase, RNA-binding protein Hfq | | Authors: | Dendooven, T, Sinha, D, Roesoleva, A, Cameron, T.A, De Lay, N, Luisi, B.F, Bandyra, K. | | Deposit date: | 2021-05-06 | | Release date: | 2021-07-07 | | Last modified: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation.
Mol.Cell, 81, 2021
|
|
7OGL
 | | A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. apo-PNPase | | Descriptor: | Polyribonucleotide nucleotidyltransferase | | Authors: | Dendooven, T, Sinha, D, Roesoleva, A, Cameron, T.A, De Lay, N, Luisi, B.F, Bandyra, K. | | Deposit date: | 2021-05-06 | | Release date: | 2021-07-07 | | Last modified: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation.
Mol.Cell, 81, 2021
|
|
7OGK
 | | A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. PNPase-3'ETS(leuZ) | | Descriptor: | 3'ETS(LeuZ), Polyribonucleotide nucleotidyltransferase | | Authors: | Dendooven, T, Sinha, D, Roesoleva, A, Cameron, T.A, De Lay, N, Luisi, B.F, Bandyra, K. | | Deposit date: | 2021-05-06 | | Release date: | 2021-07-07 | | Last modified: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation.
Mol.Cell, 81, 2021
|
|
7ML2
 | | RNA polymerase II pre-initiation complex (PIC3) | | Descriptor: | BJ4_G0004860.mRNA.1.CDS.1, BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, ... | | Authors: | Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. | | Deposit date: | 2021-04-27 | | Release date: | 2022-02-02 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
|
|
7ML4
 | | RNA polymerase II initially transcribing complex (ITC) | | Descriptor: | BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. | | Deposit date: | 2021-04-27 | | Release date: | 2022-02-02 | | Last modified: | 2022-03-09 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
|
|
7ML1
 | | RNA polymerase II pre-initiation complex (PIC2) | | Descriptor: | BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. | | Deposit date: | 2021-04-27 | | Release date: | 2022-02-02 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
|
|
7ML0
 | | RNA polymerase II pre-initiation complex (PIC1) | | Descriptor: | BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. | | Deposit date: | 2021-04-27 | | Release date: | 2022-02-02 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
|
|
7MKA
 | | Structure of EC+EC (leading EC-focused) | | Descriptor: | DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Yang, C, Murakami, K. | | Deposit date: | 2021-04-22 | | Release date: | 2022-04-27 | | Last modified: | 2023-05-17 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
|
|
7MK9
 | | Complex structure of trailing EC of EC+EC (trailing EC-focused) | | Descriptor: | DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Yang, C, Murakami, K. | | Deposit date: | 2021-04-22 | | Release date: | 2022-04-27 | | Last modified: | 2023-05-17 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
|
|
7ENA
 | | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | | Deposit date: | 2021-04-16 | | Release date: | 2021-05-26 | | Last modified: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (4.07 Å) | | Cite: | Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
|
|
7ENC
 | | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | | Deposit date: | 2021-04-16 | | Release date: | 2021-05-26 | | Last modified: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (4.13 Å) | | Cite: | Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
|
|
7O75
 | | Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-13 | | Release date: | 2021-06-16 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
|
|
7O73
 | | Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-12 | | Release date: | 2021-06-16 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
|
|
7O72
 | | Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-12 | | Release date: | 2021-06-16 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
|
|
7O4J
 | | Yeast RNA polymerase II transcription pre-initiation complex (consensus) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-06 | | Release date: | 2021-06-16 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
|
|
