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7ZRB
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BU of 7zrb by Molmil
Crystal structure of Beta-catenin Armadillo repeats domain in complex with the inhibitor RS6452
Descriptor: 4-bromanyl-~{N}-(3-pyridin-2-ylphenyl)benzenesulfonamide, Catenin beta-1
Authors:Capelli, D, Pochetti, G, Montanari, R.
Deposit date:2022-05-04
Release date:2023-05-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.434 Å)
Cite:Novel N -(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the beta-Catenin Armadillo Repeats Domain as an Anticancer Agent.
Acs Pharmacol Transl Sci, 6, 2023
5TBK
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BU of 5tbk by Molmil
Crystal structure of human importin a3 bound to RCC1
Descriptor: Importin subunit alpha-3, Regulator of chromosome condensation
Authors:Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
5ZHX
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BU of 5zhx by Molmil
Crystal structure of SmgGDS-558 and farnesylated RhoA complex
Descriptor: FARNESYL, Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA
Authors:Shimizu, H, Toma-Fukai, S, Shimizu, T.
Deposit date:2018-03-13
Release date:2018-09-05
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3FEX
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BU of 3fex by Molmil
Crystal structure of the CBC-importin alpha complex.
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
Authors:Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.549 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
8EIA
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BU of 8eia by Molmil
Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H333, a Helicon Polypeptide
Descriptor: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H333, ...
Authors:Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
Deposit date:2022-09-14
Release date:2023-10-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
7N6G
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BU of 7n6g by Molmil
C1 of central pair
Descriptor: CPC1, Calmodulin, DPY30, ...
Authors:Han, L, Zhang, K.
Deposit date:2021-06-08
Release date:2022-05-18
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of an active central apparatus.
Nat.Struct.Mol.Biol., 29, 2022
8EIB
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BU of 8eib by Molmil
Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H329, a Helicon Polypeptide
Descriptor: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H329, ...
Authors:Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
Deposit date:2022-09-14
Release date:2023-10-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.76 Å)
Cite:Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
7SQC
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BU of 7sqc by Molmil
Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CPC1, Calmodulin, ...
Authors:Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R.
Deposit date:2021-11-05
Release date:2022-04-13
Last modified:2022-06-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ciliary central apparatus structure reveals mechanisms of microtubule patterning.
Nat.Struct.Mol.Biol., 29, 2022
8EI9
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BU of 8ei9 by Molmil
Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H332, a Helicon Polypeptide
Descriptor: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H332, ...
Authors:Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
Deposit date:2022-09-14
Release date:2023-10-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8GCN
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BU of 8gcn by Molmil
CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER
Descriptor: Importin subunit alpha-1, Importin subunit beta-1
Authors:Ko, Y, Cingolani, G.
Deposit date:2023-03-02
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER
To Be Published
8J07
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BU of 8j07 by Molmil
96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
Descriptor: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
Authors:Gui, M, Brown, A.
Deposit date:2023-04-09
Release date:2023-07-26
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
6N88
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BU of 6n88 by Molmil
Cryo-EM structure of the Importin7:Importin beta:Histone H1.0 complex
Descriptor: Histone H1.0, Importin subunit beta-1, MGC52556 protein
Authors:Bilokapic, S, Ivic, N, Halic, M.
Deposit date:2018-11-28
Release date:2019-02-27
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Fuzzy Interactions Form and Shape the Histone Transport Complex.
Mol. Cell, 73, 2019
6N89
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BU of 6n89 by Molmil
Cryo-EM structure of the Importin beta:Histone H1.0 complex
Descriptor: Histone H1.0, Importin subunit beta-1
Authors:Bilokapic, S, Ivic, N, Halic, M.
Deposit date:2018-11-28
Release date:2019-02-27
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Fuzzy Interactions Form and Shape the Histone Transport Complex.
Mol. Cell, 73, 2019

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건을2024-05-08부터공개중

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