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8TJ4	CRYSTAL STRUCTURE OF THE A/Bangkok/1/1979(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8SK7	Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA_20 minibinder (RFdiffusion-designed), ... Authors: Borst, A.J, Bennett, N.R. Deposit date: 2023-04-18 Release date: 2023-06-14 Last modified: 2023-09-13 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: De novo design of protein structure and function with RFdiffusion. Nature, 620, 2023
8SJ9	Crystal structure of the H1 hemagglutinin COBRA X6 Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Dzimianski, J.V, DuBois, R.M. Deposit date: 2023-04-17 Release date: 2024-05-01 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Structural basis for the expanded antibody breadth against X6, a broadly reactive H1 hemagglutinin vaccine To Be Published
8PK3	CryoEM reconstruction of hemagglutinin HK68 of Influenza A virus bound to an Affimer reagent Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer molecule (A31), ... Authors: Debski-Antoniak, O, Flynn, A, Klebl, D.P, Tiede, C, Muench, S, Tomlinson, D, Fontana, J. Deposit date: 2023-06-24 Release date: 2024-01-03 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Exploiting the Affimer platform against influenza A virus To Be Published
8IV0	H7N9 HA-C4H4 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C4H4 Fab heavy chain, C4H4 Fab light chain, ... Authors: Zhao, B.B, Sun, Z.Z. Deposit date: 2023-03-25 Release date: 2024-04-24 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: H7N9 HA-C4H4 Fab To Be Published
8IUZ	H7N9 HA-2D7 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2D7 Fab heavy chain, 2D7 Fab light chain, ... Authors: Zhao, B.B, Sun, Z.Z. Deposit date: 2023-03-25 Release date: 2024-04-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: H7N9 HA-2D7 Fab To Be Published
8IUY	H7N9 HA-1H9 Fab Descriptor: 1H9 Fab heavy chain, 1H9 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zhao, B.B, Sun, Z.Z. Deposit date: 2023-03-25 Release date: 2024-04-24 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: H7N9 HA-1H9 Fab To Be Published
8IUX	The cryoEM structure of H7N9-HA protein Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Zhao, B.B, Sun, Z.Z. Deposit date: 2023-03-25 Release date: 2024-04-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: The cryoEM structure of H7N9-HA protein To Be Published
8GV7	Crystal structure of PN-SIA28 in complex with influenza hemagglutinin H18 A/flat-faced bat/Peru/033/2010 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin H18-HA1, ... Authors: Chen, Y, Song, H, Qi, J, Gao, G.F. Deposit date: 2022-09-14 Release date: 2022-12-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
8GV6	Crystal structure of PN-SIA28 in complex with influenza hemagglutinin H14 (A/long-tailed duck/Wisconsin/10OS3912/2010) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin H14-HA1, ... Authors: Chen, Y, Song, H, Qi, J, Gao, G.F. Deposit date: 2022-09-14 Release date: 2022-12-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
8GV5	Crystal structure of PN-SIA28 in complex with influenza hemagglutinin A/swine/Guangdong/104/2013 (H1N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... Authors: Chen, Y, Song, H, Qi, J, Gao, G.F. Deposit date: 2022-09-14 Release date: 2022-12-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
8G5B	Influenza A H3N2 X-31 Hemagglutinin in complex with FL-1061 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FL-1061 heavy chain, FL-1061 light chain, ... Authors: Windsor, I.W, Thornlow, D, Schmidt, A.G. Deposit date: 2023-02-12 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Fabs elicited by hyperglycosylated immunogen To Be Published
8G5A	X-31 hemagglutinin in complex with FL-1061 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FL-1086 Fab heavy chain, FL-1086 light chain, ... Authors: Windsor, I.W, Thornlow, D, Schmidt, A.G. Deposit date: 2023-02-12 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Antibodies elicited by a hyperglycoslated immunogen To Be Published
8F38	Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-11-09 Release date: 2023-12-13 Method: ELECTRON MICROSCOPY (2.64 Å) Cite: Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab To be published
8DIU	Cryo-EM structure of influenza A virus A/Bayern/7/1995 hemagglutinin bound to CR6261 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-06-29 Release date: 2022-12-14 Method: ELECTRON MICROSCOPY (2.61 Å) Cite: CryoEM structure of influenza A virus A/Bayern/7/1995 hemagglutinin bound to CR6261 Fab To be published
8DIS	CryoEM structure of Influenza A virus A/Melbourne/1/1946 (H1N1) hemagglutinin bound to CR6261 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-06-29 Release date: 2023-06-07 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: CryoEM structure of Influenza A virus A/Melbourne/1/1946 (H1N1) hemagglutinin bound to CR6261 Fab To be published
8DIM	CryoEM structure of Influenza A virus A/Ohio/09/2015 hemagglutinin bound to CR6261 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, CR6261 Fab light chain, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-06-29 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: CryoEM structure of Influenza A virus A/Ohio/09/2015 hemagglutinin bound to CR6261 Fab To Be Published
8D21	Cryo-EM structure of the VRC321 clinical trial, vaccine-elicited, human antibody 1B06 in complex with a stabilized NC99 HA trimer Descriptor: 1B06 Heavy Chain, 1B06 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2022-05-27 Release date: 2023-04-12 Last modified: 2023-05-03 Method: ELECTRON MICROSCOPY (3.96 Å) Cite: An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans. Sci Transl Med, 15, 2023
7ZJ8	X-31 Hemagglutinin Precursor HA0 at pH 7.5 after reneutralization Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,Fibritin, ... Authors: Garcia-Moro, E, Rosenthal, P.B. Deposit date: 2022-04-08 Release date: 2022-08-17 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Reversible structural changes in the influenza hemagglutinin precursor at membrane fusion pH. Proc.Natl.Acad.Sci.USA, 119, 2022
7ZJ7	X-31 Hemagglutinin Precursor HA0 at pH 4.8 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,Fibritin, ... Authors: Garcia-Moro, E, Rosenthal, P.B. Deposit date: 2022-04-08 Release date: 2022-08-17 Method: ELECTRON MICROSCOPY (3.95 Å) Cite: Reversible structural changes in the influenza hemagglutinin precursor at membrane fusion pH. Proc.Natl.Acad.Sci.USA, 119, 2022
7ZJ6	X-31 Hemagglutinin Precursor HA0 at pH 7.5 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,Fibritin, ... Authors: Garcia-Moro, E, Rosenthal, P.B. Deposit date: 2022-04-08 Release date: 2022-08-17 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Reversible structural changes in the influenza hemagglutinin precursor at membrane fusion pH. Proc.Natl.Acad.Sci.USA, 119, 2022
7YHK	Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5 Descriptor: 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zheng, Q, Li, S, Li, T, Xue, W, Sun, H. Deposit date: 2022-07-13 Release date: 2022-08-17 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
7X6O	Cryo-EM structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 28-12 Descriptor: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of antibody 12 fab Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-07 Release date: 2022-03-23 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus. Nat Commun, 13, 2022
7X6L	Cryo-EM structure of H3 hemagglutinin from A/HongKong/01/1968 in complex with a neutralizing antibody 28-12 Descriptor: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of the antibody 12 fab Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-07 Release date: 2022-03-23 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus. Nat Commun, 13, 2022
7WVG	Crystal structure of H18 complexed with SIA28 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... Authors: Chen, Y, Qi, J, Gao, G.F. Deposit date: 2022-02-10 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022

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