5VHC
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5VHA
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5V9X
| Structure of Mycobacterium smegmatis helicase Lhr bound to ssDNA and AMP-PNP | 分子名称: | ATP-dependent DNA helicase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Ordonez, H, Jacewicz, A, Ferrao, R, Shuman, S. | 登録日 | 2017-03-23 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.797 Å) | 主引用文献 | Structure of mycobacterial 3'-to-5' RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases. Nucleic Acids Res., 46, 2018
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5URM
| Crystal structure of human BRR2 in complex with T-1206548 | 分子名称: | 3-(5-{[(2R)-5-amino-2-cyclohexyl-7-oxo-2,3-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-yl]methyl}furan-2-yl)benzoic acid, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Klein, M.G, Tjhen, R, Qin, L. | 登録日 | 2017-02-11 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J. Med. Chem., 60, 2017
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5URK
| Crystal structure of human BRR2 in complex with T-3935799 | 分子名称: | 6-benzyl-3-[3-(benzyloxy)phenyl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(1H,3H)-dione, GLYCEROL, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Qin, L, Tjhen, R, Klein, M.G. | 登録日 | 2017-02-10 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J. Med. Chem., 60, 2017
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5URJ
| Crystal structure of human BRR2 in complex with T-3905516 | 分子名称: | 6-benzyl-3-[(2R)-2-(3-fluoropyridin-2-yl)-6-methyl-3,4-dihydro-2H-1-benzopyran-7-yl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(3H,8H)-dione, GLYCEROL, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Klein, M.G, Tjhen, R, Qin, L. | 登録日 | 2017-02-10 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J. Med. Chem., 60, 2017
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5SUQ
| Crystal structure of the THO-Sub2 complex | 分子名称: | 12-TUNGSTOPHOSPHATE, ATP-dependent RNA helicase SUB2, Tex1, ... | 著者 | Ren, Y, Blobel, G. | 登録日 | 2016-08-03 | 公開日 | 2017-01-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (6 Å) | 主引用文献 | Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1. Elife, 6, 2017
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5SUP
| Crystal structure of the Sub2-Yra1 complex in association with RNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase SUB2, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Ren, Y, Schmiege, P, Blobel, G. | 登録日 | 2016-08-03 | 公開日 | 2017-01-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1. Elife, 6, 2017
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5OOQ
| Structure of the Mtr4 Nop53 Complex | 分子名称: | ATP-dependent RNA helicase DOB1, Ribosome biogenesis protein NOP53, SULFATE ION | 著者 | Falk, S, Basquin, J, Conti, E. | 登録日 | 2017-08-08 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53. RNA, 23, 2017
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5O9Z
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5NRL
| Structure of a pre-catalytic spliceosome. | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | 著者 | Plaschka, C, Lin, P.-C, Nagai, K. | 登録日 | 2017-04-24 | 公開日 | 2017-05-31 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Structure of a pre-catalytic spliceosome. Nature, 546, 2017
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5N9F
| Crystal Structure of Drosophila DHX36 helicase in complex with ssDNA CpG_A | 分子名称: | CG9323, isoform A, CHLORIDE ION, ... | 著者 | Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.969 Å) | 主引用文献 | Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
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5N9E
| Crystal Structure of Drosophila DHX36 helicase in complex with TGGGGATTT | 分子名称: | CG9323, isoform A, DNA (5'-D(P*TP*GP*GP*GP*GP*AP*TP*TP*T)-3') | 著者 | Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.007 Å) | 主引用文献 | Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
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5N9D
| Crystal Structure of Drosophila DHX36 helicase in complex with GGGTTAGGGT | 分子名称: | CG9323, isoform A, DNA (5'-D(P*GP*GP*GP*TP*TP*AP*GP*GP*GP*T)-3') | 著者 | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5N9A
| Crystal Structure of Drosophila DHX36 helicase in complex with GTTAGGGTT | 分子名称: | CG9323, isoform A, DNA (5'-D(P*GP*TP*TP*AP*GP*GP*GP*TP*T)-3') | 著者 | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.036 Å) | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5N98
| Crystal Structure of Drosophila DHX36 helicase in complex with TAGGGTTTT | 分子名称: | CG9323, isoform A, DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*TP*T)-3'), ... | 著者 | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.756 Å) | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5N96
| Crystal Structure of Drosophila DHX36 helicase in complex with AGGGTTTTTT | 分子名称: | CG9323, isoform A, DNA (5'-D(P*AP*GP*GP*GP*TP*TP*TP*TP*TP*T)-3'), ... | 著者 | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.716 Å) | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5N94
| Crystal Structure of Drosophila DHX36 helicase in complex with polyU | 分子名称: | CG9323, isoform A, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*U)-3') | 著者 | Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.428 Å) | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5N90
| Crystal Structure of Drosophila DHX36 helicase in complex with TTGTGGTGT | 分子名称: | CG9323, isoform A, DNA (5'-D(P*TP*TP*GP*TP*GP*GP*TP*GP*T)-3'), ... | 著者 | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.069 Å) | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5N8Z
| Crystal Structure of Drosophila DHX36 helicase in complex with CTCTCCCTT | 分子名称: | CG9323, isoform A, DNA (5'-D(P*CP*TP*CP*TP*CP*CP*CP*TP*T)-3'), ... | 著者 | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.477 Å) | 主引用文献 | Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
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5N8U
| Crystal Structure of Drosophila DHX36 helicase in complex with CTCTCCT | 分子名称: | CG9323, isoform A, DNA (5'-D(P*CP*TP*CP*TP*CP*CP*CP*T)-3'), ... | 著者 | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
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5N8S
| Crystal Structure of Drosophila DHX36 helicase in complex with polyT | 分子名称: | CG9323, isoform A, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | 著者 | Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5N8R
| Crystal Structure of Drosophilia DHX36 helicase in complex with GAGCACTGC | 分子名称: | CG9323, isoform A, DNA (5'-D(P*GP*AP*GP*CP*AP*CP*TP*GP*C)-3') | 著者 | Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | 登録日 | 2017-02-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. Structure, 26, 2018
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5MQF
| Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ... | 著者 | Bertram, K, Hartmuth, K, Kastner, B. | 登録日 | 2016-12-20 | 公開日 | 2017-03-22 | 最終更新日 | 2018-11-21 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature, 542, 2017
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5MQ0
| Structure of a spliceosome remodeled for exon ligation | 分子名称: | 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ... | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | 登録日 | 2016-12-19 | 公開日 | 2017-01-18 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | 主引用文献 | Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
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