8WOU
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8WKJ
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7SZP
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8TN3
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8TN2
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8SKR
| human liver mitochondrial Aspartate aminotransferase | Descriptor: | Aspartate aminotransferase, mitochondrial, PYRIDOXAL-5'-PHOSPHATE | Authors: | Zhang, Z, Tringides, M. | Deposit date: | 2023-04-20 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology. Mol.Cell Proteomics, 22, 2023
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7POA
| An Irreversible, Promiscuous and Highly Thermostable Claisen-Condensation Biocatalyst Drives the Synthesis of Substituted Pyrroles | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Basle, A, Ashley, B, Campopiano, D, Marles-Wright, J. | Deposit date: | 2021-09-08 | Release date: | 2022-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Versatile Chemo-Biocatalytic Cascade Driven by a Thermophilic and Irreversible C-C Bond-Forming alpha-Oxoamine Synthase. Acs Sustain Chem Eng, 11, 2023
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7POC
| An Irreversible, Promiscuous and Highly Thermostable Claisen-Condensation Biocatalyst Drives the Synthesis of Substituted Pyrroles | Descriptor: | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Basle, A, Ashley, B, Campopiano, D, Marles-Wright, J. | Deposit date: | 2021-09-08 | Release date: | 2022-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Versatile Chemo-Biocatalytic Cascade Driven by a Thermophilic and Irreversible C-C Bond-Forming alpha-Oxoamine Synthase. Acs Sustain Chem Eng, 11, 2023
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7POB
| An Irreversible, Promiscuous and Highly Thermostable Claisen-Condensation Biocatalyst Drives the Synthesis of Substituted Pyrroles | Descriptor: | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION | Authors: | Basle, A, Ashley, B, Campopiano, D, Marles-Wright, J. | Deposit date: | 2021-09-08 | Release date: | 2022-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Versatile Chemo-Biocatalytic Cascade Driven by a Thermophilic and Irreversible C-C Bond-Forming alpha-Oxoamine Synthase. Acs Sustain Chem Eng, 11, 2023
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4M2M
| Crystal structure of PLP-dependent cyclase OrfR in complex with PLP-L-Arg | Descriptor: | ARGININE, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | Deposit date: | 2013-08-05 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl., 53, 2014
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4M2K
| Crystal structure of PLP-dependent cyclase OrfR in complex with PLP | Descriptor: | Aminotransferase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | Deposit date: | 2013-08-05 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl., 53, 2014
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4M2J
| Crystal structure of PLP-dependent cyclase OrfR in complex with Au | Descriptor: | Aminotransferase, GOLD ION, PYRIDOXAL-5'-PHOSPHATE | Authors: | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | Deposit date: | 2013-08-05 | Release date: | 2014-06-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl., 53, 2014
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7TUR
| Joint X-ray/neutron structure of aspastate aminotransferase (AAT) in complex with pyridoxamine 5'-phosphate (PMP) | Descriptor: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase, ... | Authors: | Drago, V.N, Kovalevsky, A.Y, Dajnowicz, S, Mueser, T.C. | Deposit date: | 2022-02-03 | Release date: | 2022-09-28 | Last modified: | 2023-10-25 | Method: | NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION | Cite: | An N⋯H⋯N low-barrier hydrogen bond preorganizes the catalytic site of aspartate aminotransferase to facilitate the second half-reaction. Chem Sci, 13, 2022
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7U7H
| Cysteate acyl-ACP transferase from Alistipes finegoldii | Descriptor: | 7-keto-8-aminopelargonate synthetase-like enzyme, PYRIDOXAL-5'-PHOSPHATE | Authors: | Radka, C.D, Miller, D.J, Frank, M.W, Rock, C.O. | Deposit date: | 2022-03-07 | Release date: | 2023-01-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii. J.Biol.Chem., 298, 2022
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4MY5
| Crystal structure of the aromatic amino acid aminotransferase from Streptococcus mutants | Descriptor: | Putative amino acid aminotransferase | Authors: | Cong, X, Li, X, Ge, J, Feng, Y, Feng, X, Li, S. | Deposit date: | 2013-09-27 | Release date: | 2014-10-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | Crystal structure of the aromatic-amino-acid aminotransferase from Streptococcus mutans. Acta Crystallogr.,Sect.F, 75, 2019
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7RGB
| O2-, PLP-dependent desaturase Plu4 product-bound enzyme | Descriptor: | (2Z,4E)-5-carbamimidamido-2-iminopent-4-enoic acid, 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Hoffarth, E.R, Ryan, K.S. | Deposit date: | 2021-07-14 | Release date: | 2021-10-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. Proc.Natl.Acad.Sci.USA, 118, 2021
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7RF9
| O2-, PLP-dependent desaturase Plu4 intermediate-bound enzyme | Descriptor: | (2E)-5-carbamimidamido-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}pentanoic acid, 1,2-ETHANEDIOL, 2-(2-ETHOXYETHOXY)ETHANOL, ... | Authors: | Hoffarth, E.R, Ryan, K.S. | Deposit date: | 2021-07-13 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.926 Å) | Cite: | A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. Proc.Natl.Acad.Sci.USA, 118, 2021
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7V58
| Structural insights into the substrate selectivity of acyl-CoA transferase | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-amino-3-ketobutyrate coenzyme A ligase, GLYCINE, ... | Authors: | Chang, H.Y, Ko, T.P. | Deposit date: | 2021-08-16 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural insights into the substrate selectivity of alpha-oxoamine synthases from marine Vibrio sp. QWI-06. Colloids Surf B Biointerfaces, 210, 2022
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7V5I
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7S5M
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7VRX
| Pad-1 in the absence of substrate | Descriptor: | Aminotransferase, SULFATE ION | Authors: | Choi, M, Rhee, S. | Deposit date: | 2021-10-25 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.96634674 Å) | Cite: | Structural and biochemical basis for the substrate specificity of Pad-1, an indole-3-pyruvic acid aminotransferase in auxin homeostasis. J.Struct.Biol., 214, 2022
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4R2N
| Crystal structure of Rv3772 in complex with its substrate | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PHENYLALANINE, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Nasir, N, Anant, A, Vyas, R, Biswal, B.K. | Deposit date: | 2014-08-12 | Release date: | 2015-08-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities Sci Rep, 6, 2016
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4RAE
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4R8D
| Crystal structure of Rv1600 encoded aminotransferase in complex with PLP-MES from Mycobacterium tuberculosis | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Histidinol-phosphate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Nasir, N, Anant, A, Vyas, R, Biswal, B.K. | Deposit date: | 2014-09-01 | Release date: | 2015-09-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of Rv1600 encoded aminotransferase in complex with PLP-MES from Mycobacterium tuberculosis To be Published
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4R5Z
| Crystal structure of Rv3772 encoded aminotransferase | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | Nasir, N, Anant, A, Vyas, R, Biswal, B.K. | Deposit date: | 2014-08-22 | Release date: | 2015-08-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities Sci Rep, 6, 2016
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