PDB: 505 件ウェブページステータス検索Chemie searchBIRD

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4WLH	High resolution crystal structure of human kynurenine aminotransferase-I bound to PLP cofactor 分子名称: Kynurenine--oxoglutarate transaminase 1 著者 Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. 登録日 2014-10-07 公開日 2014-12-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate. Protein Sci., 26, 2017
7N79	O2-, PLP-dependent desaturase Plu4 holo-enzyme 分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... 著者 Hoffarth, E.R, Ryan, K.S. 登録日 2021-06-09 公開日 2021-10-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. Proc.Natl.Acad.Sci.USA, 118, 2021
6UXZ	(S)-4-Amino-5-phenoxypentanoate as a Selective Agonist of the Transcription Factor GabR 分子名称: (4S)-4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-5-phenoxypentanoic acid, HTH-type transcriptional regulatory protein GabR, SULFATE ION 著者 Catlin, D.S, Liu, D. 登録日 2019-11-09 公開日 2020-10-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 (S)-4-Amino-5-phenoxypentanoate designed as a potential selective agonist of the bacterial transcription factor GabR. Protein Sci., 29, 2020
6ONN	Crystal structure of 8-amino-7-oxononanoate synthase from Burkholderia phymatum 分子名称: 8-amino-7-oxononanoate synthase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-04-22 公開日 2019-05-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of 8-amino-7-oxononanoate synthase from Burkholderia phymatum To be published
5JAY	Crystal Structure of an 8-amino-7-oxononanoate Synthase from Burkholderia xenovorans 分子名称: 8-amino-7-oxononanoate synthase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-04-12 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of an 8-amino-7-oxononanoate Synthase from Burkholderia xenovorans to be published
7AAT	X-RAY STRUCTURE REFINEMENT AND COMPARISON OF THREE FORMS OF MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE 分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Mcphalen, C.A, Vincent, M.G, Jansonius, J.N. 登録日 1991-12-02 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase. J.Mol.Biol., 225, 1992
6ZUP	Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - L-(-)-3-phenyllactic acid 分子名称: ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, Aminotransferase, MAGNESIUM ION, ... 著者 Bujacz, A, Rum, J, Rutkiewicz, M, Pietrzyk-Brzezinska, A.J, Bujacz, G. 登録日 2020-07-23 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6. Materials (Basel), 14, 2021
6ZVG	Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - L-indole-3-lactic acid 分子名称: 3-(INDOL-3-YL) LACTATE, Aminotransferase, MAGNESIUM ION, ... 著者 Rum, J, Rutkiewicz, M, Pruska, A, Bujacz, A, Pietrzyk-Brzezinska, A.J, Bujacz, G. 登録日 2020-07-24 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6. Materials (Basel), 14, 2021
6ZUR	Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - L-p-hydroxyphenyllactic acid 分子名称: (2S)-2-hydroxy-3-(4-hydroxyphenyl)propanoic acid, Aminotransferase, MAGNESIUM ION, ... 著者 Bujacz, A, Rum, J, Rutkiewicz, M, Pietrzyk-Brzezinska, A.J, Bujacz, G. 登録日 2020-07-23 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6. Materials (Basel), 14, 2021
4WB0	Crystal structure of the broad specificity aminotransferase from Leishmania mexicana 分子名称: Broad specificity aminotransferase, CACODYLATE ION 著者 Wen, J, Nowicki, C, Blankenfeldt, W. 登録日 2014-09-02 公開日 2015-09-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural basis for the relaxed substrate selectivity of Leishmania mexicana broad specificity aminotransferase. Mol.Biochem.Parasitol., 202, 2015
4W5K	Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei, K237A mutant 分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase, mitochondrial, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-08-18 公開日 2014-09-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr.,Sect.F, 71, 2015
6QP3	Crystal structure of the PLP-bound C-S lyase from Bacillus subtilis (strain 168) 分子名称: ACETATE ION, Cystathionine beta-lyase PatB, PYRIDOXAL-5'-PHOSPHATE 著者 Herman, R, Rudden, M, Wilkinson, A.J, Hanai, S, Thomas, G.H. 登録日 2019-02-13 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The molecular basis of thioalcohol production in human body odour. Sci Rep, 10, 2020
4WBT	Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Shabalin, I.G, Bacal, P, Kowalska, A.K, Cooper, D.R, Stead, M, Hammonds, J, Ahmed, M, Hillerich, B.S, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2014-09-03 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate to be published
2F8J	Crystal structure of Histidinol-phosphate aminotransferase (EC 2.6.1.9) (Imidazole acetol-phosphate transferase) (tm1040) from Thermotoga maritima at 2.40 A resolution 分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Histidinol-phosphate aminotransferase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2005-12-02 公開日 2006-02-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Histidinol-phosphate aminotransferase (EC 2.6.1.9) (Imidazole acetol-phosphate transferase) (tm1040) from Thermotoga maritima at 2.40 A resolution To be published
4WP0	Crystal structure of human kynurenine aminotransferase-I with a C-terminal V5-hexahistidine tag 分子名称: Kynurenine--oxoglutarate transaminase 1 著者 Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. 登録日 2014-10-17 公開日 2014-11-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of human kynurenine aminotransferase-I in a novel space group To be published
4WLJ	High resolution crystal structure of human kynurenine aminotransferase-I in complex with aminooxyacetate 分子名称: 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, Kynurenine--oxoglutarate transaminase 1 著者 Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. 登録日 2014-10-07 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate. Protein Sci., 26, 2017
2G6W	Suicide inhibition of a-Oxamine Synthase: Structures of the Covalent Adducts of 8-Amino-7-oxonanoate Synthase with trifluoroalanine 分子名称: (4-{(E)-[(2,2-DIFLUOROETHYL)IMINO]METHYL}-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 8-amino-7-oxononanoate synthase 著者 Alexeev, D. 登録日 2006-02-26 公開日 2006-04-25 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Suicide inhibition of alpha-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine. Org.Biomol.Chem., 4, 2006
2GB3	Crystal structure of Aspartate aminotransferase (tm1698) from Thermotoga maritima at 2.50 A resolution 分子名称: aspartate aminotransferase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-03-09 公開日 2006-03-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of Aspartate aminotransferase (tm1698) from Thermotoga maritima at 2.50 A resolution To be published
6S8W	Aromatic aminotransferase AroH (Aro8) form Aspergillus fumigatus in complex with PLP (internal aldimine) 分子名称: Aromatic aminotransferase Aro8, putative, FORMIC ACID, ... 著者 Giardina, G, Mirco, D, Spizzichino, S, Zelante, T, Cutruzzola, F, Romani, L, Cellini, B. 登録日 2019-07-10 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase Proteins, 2021
6T8P	HKATII IN COMPLEX WITH LIGAND (2R)-N-benzyl-1-[6-methyl-5-(oxan-4-yl)-7-oxo-6H,7H-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide 分子名称: 1,2-ETHANEDIOL, 3,5-bis(fluoranyl)-~{N}-[5-[(2~{R})-2-(3-fluorophenyl)-3-methyl-butyl]-1,3,4-thiadiazol-2-yl]benzenesulfonamide, IODIDE ION, ... 著者 Blaesse, M, Venalainen, J. 登録日 2019-10-24 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
6T3V	Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - malic acid 分子名称: (2S)-2-hydroxybutanedioic acid, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Rutkiewicz, M, Bujacz, A, Rum, J, Bujacz, G. 登録日 2019-10-11 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6. Materials, 14, 2021
6T8Q	HKATII IN COMPLEX WITH LIGAND (2R)-N-benzyl-1-[6-methyl-5-(oxan-4-yl)-7-oxo-6H,7H-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide 分子名称: (2~{R})-1-[6-methyl-5-(oxan-4-yl)-7-oxidanylidene-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]-~{N}-(phenylmethyl)pyrrolidine-2-carboxamide, ACETATE ION, CADMIUM ION, ... 著者 Blaesse, M, Venalainen, J. 登録日 2019-10-24 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
2JG2	HIGH RESOLUTION STRUCTURE OF SPT WITH PLP INTERNAL ALDIMINE 分子名称: MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE 著者 Yard, B.A, Carter, L.G, Johnson, K.A, Overton, I.M, Mcmahon, S.A, Dorward, M, Liu, H, Puech, D, Oke, M, Barton, G.J, Naismith, J.H, Campopiano, D.J. 登録日 2007-02-07 公開日 2007-05-01 最終更新日 2015-11-11 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The Structure of Serine Palmitoyltransferase; Gateway to Sphingolipid Biosynthesis. J.Mol.Biol., 370, 2007
2JGT	Low resolution structure of SPT 分子名称: SERINE PALMITOYLTRANSFERASE 著者 Yard, B.A, Carter, L.G, Johnson, K.A, Overton, I.M, Mcmahon, S.A, Dorward, M, Liu, H, Puech, D, Oke, M, Barton, G.J, Naismith, J.H, Campopiano, D.J. 登録日 2007-02-14 公開日 2007-05-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Structure of Serine Palmitoyltransferase; Gateway to Sphingolipid Biosynthesis. J.Mol.Biol., 370, 2007
9AAT	X-RAY STRUCTURE REFINEMENT AND COMPARISON OF THREE FORMS OF MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE 著者 Mcphalen, C.A, Vincent, M.G, Jansonius, J.N. 登録日 1991-12-02 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase. J.Mol.Biol., 225, 1992

 

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