PDB: 117 件ウェブページステータス検索Chemie searchBIRD

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8TE4	Crystal structure of the methyltransferase domain of R882H/N879A DNMT3A homotetramer 分子名称: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE 著者 Lu, J.W, Song, J.K. 登録日 2023-07-05 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of the methyltransferase domain of R882H/N879A DNMT3A homotetramer To Be Published
6KDL	Crystal structure of human DNMT3B-DNMT3L complex (I) 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE 著者 Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. 登録日 2019-07-02 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.274 Å) 主引用文献 Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDP	Crystal structure of human DNMT3B-DNMT3L complex (II) 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... 著者 Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. 登録日 2019-07-02 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDB	Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpT site 分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. 登録日 2019-07-01 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.862 Å) 主引用文献 Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDT	Crystal structure of human DNMT3B (Q772R)-DNMT3L complex 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... 著者 Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. 登録日 2019-07-02 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDA	Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpG site 分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. 登録日 2019-07-01 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.909 Å) 主引用文献 Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
7L4C	Crystal structure of the DRM2-CTT DNA complex 分子名称: DNA (5'-D(*AP*TP*TP*AP*TP*TP*AP*AP*TP*(C49)P*TP*TP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*AP*AP*GP*AP*TP*TP*AP*AP*TP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... 著者 Fang, J, Song, J. 登録日 2020-12-18 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
7L4K	Crystal structure of the DRM2-CCG DNA complex 分子名称: DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*CP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*GP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... 著者 Fang, J, Song, J. 登録日 2020-12-19 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
7L4H	Crystal structure of the DRM2-CTG DNA complex 分子名称: DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*TP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*AP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... 著者 Fang, J, Song, J. 登録日 2020-12-19 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
7L4N	Crystal structure of the DRM2 (C397R)-CCG DNA complex 分子名称: DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*CP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*GP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... 著者 Fang, J, Song, J. 登録日 2020-12-19 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.247 Å) 主引用文献 Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
7L4M	Crystal structure of the DRM2-CCT DNA complex 分子名称: DNA (5'-D(*TP*AP*AP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*AP*T)-3'), DNA (5'-D(P*AP*TP*TP*CP*CP*TP*CP*CP*TP*(C49)P*CP*TP*CP*CP*TP*TP*TP*A)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... 著者 Fang, J, Song, J. 登録日 2020-12-19 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.805 Å) 主引用文献 Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
7L4F	Crystal structure of the DRM2-CAT DNA complex 分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*AP*TP*TP*CP*CP*TP*CP*CP*TP*(C49)P*AP*TP*CP*CP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*GP*GP*AP*TP*GP*AP*GP*GP*AP*GP*GP*AP*AP*T)-3'), ... 著者 Fang, J, Song, J. 登録日 2020-12-19 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
6MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND DNA CONTAINING 4'-THIO-2'DEOXYCYTIDINE AT THE TARGET 分子名称: CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(4SC)P*GP*CP*AP*TP*GP*G)-3'), ... 著者 Cheng, X. 登録日 1998-08-05 公開日 1998-08-12 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase. Nucleic Acids Res., 25, 1997
2Z6A	S-Adenosyl-L-methionine-Dependent Methyl Transfer: Observable Precatalytic Intermediates during DNA Cytosine Methylation 分子名称: DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DTP*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), Modification methylase HhaI, ... 著者 Shieh, F.K. 登録日 2007-07-25 公開日 2007-08-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 S-Adenosyl-l-methionine-Dependent Methyl Transfer: Observable Precatalytic Intermediates during DNA Cytosine Methylation Biochemistry, 46, 2007
2Z6Q	Ternary structure of Arg165Ala M.HhaI C5-Cytosine DNA methyltransferase with unmodified DNA and AdoHcy 分子名称: 2'-DEOXYCYTIDINE, DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DGP*DCP*DTP*DAP*DTP*DC)-3'), ... 著者 Shieh, F.K. 登録日 2007-08-08 公開日 2007-08-28 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI J.Mol.Biol., 362, 2006
2Z6U	Ternary structure of the Glu119Ala M.HhaI, C5-Cytosine DNA methyltransferase, with unmodified DNA and AdoHcy 分子名称: DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DTP*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), Modification methylase HhaI, ... 著者 Shieh, F.K. 登録日 2007-08-09 公開日 2007-11-20 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 AdoMet-dependent Methyl-transfer: Glu(119) Is Essential for DNA C5-Cytosine Methyltransferase M.HhaI J.Mol.Biol., 373, 2007
2ZCJ	Ternary structure of the Glu119Gln M.HhaI, C5-Cytosine DNA methyltransferase, with unmodified DNA and AdoHcy 分子名称: DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DTP*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), Modification methylase HhaI, ... 著者 Shieh, F.K, Reich, N.O. 登録日 2007-11-09 公開日 2007-12-04 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 AdoMet-dependent Methyl-transfer: Glu(119) Is Essential for DNA C5-Cytosine Methyltransferase M.HhaI J.Mol.Biol., 373, 2007
6U8X	Crystal structure of DNMT3B-DNMT3L in complex with CpApG DNA 分子名称: CpApG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Song, J. 登録日 2019-09-06 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.95063877 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
6U91	Crystal structure of DNMT3B(Q772R)-DNMT3L in complex with CpGpT DNA 分子名称: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Song, J. 登録日 2019-09-06 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.99998879 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms To Be Published
6U8P	Crystal structure of DNMT3B-DNMT3L in complex with CpGpA DNA 分子名称: CpGpA DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Song, J. 登録日 2019-09-05 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
6U90	Crystal structure of DNMT3B(N779A)-DNMT3L in complex with CpGpT DNA 分子名称: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Song, J. 登録日 2019-09-06 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.00081754 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms To Be Published
6U8V	Crystal structure of DNMT3B-DNMT3L in complex with CpGpT DNA 分子名称: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Zhang, Z.M, Song, J. 登録日 2019-09-06 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
6U8W	Crystal structure of DNMT3B(K777A)-DNMT3L in complex with CpGpT DNA 分子名称: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Zhang, Z.M, Song, J. 登録日 2019-09-06 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.94891548 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
6W8B	Structure of DNMT3A in complex with CGA DNA 分子名称: CGA DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... 著者 Anteneh, H, Song, J. 登録日 2020-03-20 公開日 2020-04-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation. Nat Commun, 11, 2020
6W89	Structure of DNMT3A (R882H) in complex with CGA DNA 分子名称: CGA DNA (25-MER), CITRIC ACID, DNA (cytosine-5)-methyltransferase 3-like, ... 著者 Anteneh, H, Song, J. 登録日 2020-03-20 公開日 2020-04-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.499 Å) 主引用文献 Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation. Nat Commun, 11, 2020

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