PDB: 968 件ウェブページステータス検索Chemie searchBIRD

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1ALQ	CIRCULARLY PERMUTED BETA-LACTAMASE FROM STAPHYLOCOCCUS AUREUS PC1 分子名称: CARBONATE ION, CP254 BETA-LACTAMASE, SULFATE ION 著者 Pieper, U, Herzberg, O. 登録日 1997-06-02 公開日 1997-09-26 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Circularly permuted beta-lactamase from Staphylococcus aureus PC1. Biochemistry, 36, 1997
1AXB	TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI INHIBITED WITH AN ACYLATION TRANSITION STATE ANALOG 分子名称: TEM-1 BETA LACTAMASE, [[N-(BENZYLOXYCARBONYL)AMINO]METHYL]PHOSPHATE 著者 Maveyraud, L, Pratt, R.F, Samama, J.P. 登録日 1997-10-14 公開日 1998-10-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of an acylation transition-state analog of the TEM-1 beta-lactamase. Mechanistic implications for class A beta-lactamases. Biochemistry, 37, 1998
1BLC	INHIBITION OF BETA-LACTAMASE BY CLAVULANATE: TRAPPED INTERMEDIATES IN CRYOCRYSTALLOGRAPHIC STUDIES 分子名称: BETA-LACTAMASE, N-(1-CARBOXY-2-HYDROXY-4-OXO-BUTYL)-N-(3-OXO-CISPROPENYL)AMINE, N-(2-HYDROXY-4-OXO-BUTYL)-N-(3-OXO-TRANSPROPENYL)AMINE, ... 著者 Chen, C.C.H, Herzberg, O. 登録日 1993-09-27 公開日 1994-01-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Inhibition of beta-lactamase by clavulanate. Trapped intermediates in cryocrystallographic studies. J.Mol.Biol., 224, 1992
1BLH	STRUCTURE OF A PHOSPHONATE-INHIBITED BETA-LACTAMASE. AN ANALOG OF THE TETRAHEDRAL TRANSITION STATE(SLASH)INTERMEDIATE OF BETA-LACTAM HYDROLYSIS 分子名称: BETA-LACTAMASE, [[N-(BENZYLOXYCARBONYL)AMINO]METHYL]PHOSPHATE 著者 Chen, C.C.H, Herzberg, O. 登録日 1993-09-30 公開日 1994-08-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis. J.Mol.Biol., 234, 1993
1BLP	STRUCTURAL BASIS FOR THE INACTIVATION OF THE P54 MUTANT OF BETA-LACTAMASE FROM STAPHYLOCOCCUS AUREUS PC1 分子名称: BETA-LACTAMASE 著者 Herzberg, O. 登録日 1993-09-23 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the inactivation of the P54 mutant of beta-lactamase from Staphylococcus aureus PC1. Biochemistry, 30, 1991
1BLS	CRYSTALLOGRAPHIC STRUCTURE OF A PHOSPHONATE DERIVATIVE OF THE ENTEROBACTER CLOACAE P99 CEPHALOSPORINASE: MECHANISTIC INTERPRETATION OF A BETA-LACTAMASE TRANSITION STATE ANALOG 分子名称: (P-IODOPHENYLACETYLAMINO)METHYLPHOSPHINIC ACID, BETA-LACTAMASE 著者 Knox, J.R, Moews, P.C, Lobkovsky, E. 登録日 1993-12-17 公開日 1995-05-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog. Biochemistry, 33, 1994
1BSG	BETA-LACTAMASE FROM STREPTOMYCES ALBUS G 分子名称: ACETATE ION, BETA LACTAMASE 著者 Fonze, E, Charlier, P, Dideberg, O. 登録日 1998-07-20 公開日 1999-01-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献
1BT5	CRYSTAL STRUCTURE OF THE IMIPENEM INHIBITED TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI 分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, PROTEIN (BETA-LACTAMASE), SULFATE ION 著者 Maveyraud, L, Mourey, L, Pedelacq, J.D, Guillet, V, Kotra, L.K, Mobashery, S, Samama, J.P. 登録日 1998-09-02 公開日 1999-09-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for Clinical Longevity of Carbapenem Antibiotics in the Face of Challenge by the Common Class A Beta-Lactamases from Antibiotic-Resistant Bacteria J.Am.Chem.Soc., 120, 1998
1BTL	CRYSTAL STRUCTURE OF ESCHERICHIA COLI TEM1 BETA-LACTAMASE AT 1.8 ANGSTROMS RESOLUTION 分子名称: BETA-LACTAMASE TEM1, SULFATE ION 著者 Jelsch, C, Mourey, L, Masson, J.M, Samama, J.P. 登録日 1993-11-01 公開日 1995-01-26 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Escherichia coli TEM1 beta-lactamase at 1.8 A resolution. Proteins, 16, 1993
1BUE	NMC-A CARBAPENEMASE FROM ENTEROBACTER CLOACAE 分子名称: PROTEIN (IMIPENEM-HYDROLYSING BETA-LACTAMASE) 著者 Swaren, P, Maveyraud, L, Cabantous, S, Pedelacq, J.D, Mourey, L, Frere, J.M, Samama, J.P. 登録日 1998-09-03 公開日 1999-09-02 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 X-ray analysis of the NMC-A beta-lactamase at 1.64-A resolution, a class A carbapenemase with broad substrate specificity. J.Biol.Chem., 273, 1998
1BUL	6ALPHA-(HYDROXYPROPYL)PENICILLANATE ACYLATED ON NMC-A BETA-LACTAMASE FROM ENTEROBACTER CLOACAE 分子名称: 2-(1-CARBOXY-2-HYDROXY-2-METHYL-PROPYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NMC-A BETA-LACTAMASE 著者 Mourey, L, Swaren, P, Miyashita, K, Bulychev, A, Mobashery, S, Samama, J.P. 登録日 1998-09-04 公開日 1998-12-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Inhibition of the Nmc-A B-Lactamase by a Penicillanic Acid Derivative, and the Structural Bases for the Increase in Substrate Profile of This Antibiotic Resistance Enzyme J.Am.Chem.Soc., 120, 1998
1BZA	BETA-LACTAMASE TOHO-1 FROM ESCHERICHIA COLI TUH12191 分子名称: BETA-LACTAMASE, SULFATE ION 著者 Ibuka, A, Taguchi, A, Ishiguro, M, Fushinobu, S, Ishii, Y, Kamitori, S, Okuyama, K, Yamaguchi, K, Konno, M, Matsuzawa, H. 登録日 1998-10-28 公開日 1999-04-27 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the E166A mutant of extended-spectrum beta-lactamase Toho-1 at 1.8 A resolution. J.Mol.Biol., 285, 1999
1C3B	AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR, BENZO(B)THIOPHENE-2-BORONIC ACID (BZB) 分子名称: BENZO[B]THIOPHENE-2-BORONIC ACID, CEPHALOSPORINASE 著者 Powers, R.A, Blazquez, J, Weston, G.S, Morosini, M.I, Baquero, F, Shoichet, B.K. 登録日 1999-07-27 公開日 1999-11-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The complexed structure and antimicrobial activity of a non-beta-lactam inhibitor of AmpC beta-lactamase. Protein Sci., 8, 1999
1CEF	CEFOTAXIME COMPLEXED WITH THE STREPTOMYCES R61 DD-PEPTIDASE 分子名称: CEFOTAXIME, C3' cleaved, open, ... 著者 Knox, J.R, Kuzin, A.P. 登録日 1995-01-12 公開日 1996-10-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases. Biochemistry, 34, 1995
1CEG	CEPHALOTHIN COMPLEXED WITH DD-PEPTIDASE 分子名称: CEPHALOTHIN GROUP, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRANSPEPTIDASE 著者 Knox, J.R, Kuzin, A.P. 登録日 1995-01-12 公開日 1996-10-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases. Biochemistry, 34, 1995
1CI8	ESTERASE ESTB FROM BURKHOLDERIA GLADIOLI: AN ESTERASE WITH (BETA)-LACTAMASE FOLD. 分子名称: ISOPROPYL ALCOHOL, PROTEIN (CARBOXYLESTERASE) 著者 Wagner, U.G, Petersen, E.I, Schwab, H, Kratky, C. 登録日 1999-04-08 公開日 2001-12-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 EstB from Burkholderia gladioli: a novel esterase with a beta-lactamase fold reveals steric factors to discriminate between esterolytic and beta-lactam cleaving activity Protein Sci., 11, 2002
1CI9	DFP-INHIBITED ESTERASE ESTB FROM BURKHOLDERIA GLADIOLI 分子名称: DIISOPROPYL PHOSPHONATE, PROTEIN (CARBOXYLESTERASE) 著者 Wagner, U.G, Petersen, E.I, Schwab, H, Kratky, C. 登録日 1999-04-08 公開日 2001-12-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 EstB from Burkholderia gladioli: a novel esterase with a beta-lactamase fold reveals steric factors to discriminate between esterolytic and beta-lactam cleaving activity Protein Sci., 11, 2002
1CK3	N276D MUTANT OF ESCHERICHIA COLI TEM-1 BETA-LACTAMASE 分子名称: BETA-LACTAMASE 著者 Swaren, P, Maveyraud, L, Samama, J.P. 登録日 1999-04-27 公開日 1999-08-18 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 X-ray structure of the Asn276Asp variant of the Escherichia coli TEM-1 beta-lactamase: direct observation of electrostatic modulation in resistance to inactivation by clavulanic acid. Biochemistry, 38, 1999
1DJA	STRUCTURE OF BETA-LACTAMASE PRECURSOR, K73H MUTANT, AT 298K 分子名称: BETA-LACTAMASE 著者 Chen, C.C.H, Herzberg, O. 登録日 1996-08-13 公開日 1997-03-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1. Biochemistry, 35, 1996
1DJB	STRUCTURE OF BETA-LACTAMASE PRECURSOR, S70A MUTANT, AT 298K 分子名称: BETA-LACTAMASE 著者 Chen, C.C.H, Herzberg, O. 登録日 1996-08-13 公開日 1997-03-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1. Biochemistry, 35, 1996
1DJC	STRUCTURE OF BETA-LACTAMASE PRECURSOR, S70A MUTANT, AT 120K 分子名称: BETA-LACTAMASE, SULFATE ION 著者 Chen, C.C.H, Herzberg, O. 登録日 1996-08-13 公開日 1997-03-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1. Biochemistry, 35, 1996
1DY6	Structure of the imipenem-hydrolyzing beta-lactamase SME-1 分子名称: CARBAPENEM-HYDROLYSING BETA-LACTAMASE SME-1 著者 Sougakoff, W, L'Hermite, G, Billy, I, Guillet, V, Naas, T, Nordman, P, Jarlier, V, Delettre, J. 登録日 2000-01-27 公開日 2001-01-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structure of the Imipenem-Hydrolyzing Class a Beta-Lactamase Sme-1 from Serratia Marcescens. Acta Crystallogr.,Sect.D, 58, 2002
1E25	The high resolution structure of PER-1 class A beta-lactamase 分子名称: EXTENDED-SPECTRUM BETA-LACTAMASE PER-1, SULFATE ION 著者 Tranier, S, Bouthors, A.T, Maveyraud, L, Guillet, V, Sougakoff, W, Samama, J.P. 登録日 2000-05-17 公開日 2000-11-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The High Resolution Crystal Structure for Class a Beta-Lactamase Per-1 Reveals the Bases for its Increase in Breadth of Activity J.Biol.Chem., 275, 2000
1EI5	CRYSTAL STRUCTURE OF A D-AMINOPEPTIDASE FROM OCHROBACTRUM ANTHROPI 分子名称: D-AMINOPEPTIDASE 著者 Bompard-Gilles, C, Remaut, H, Villeret, V, Prange, T, Fanuel, L, Joris, J, Frere, J.-M, Van Beeumen, J. 登録日 2000-02-24 公開日 2000-10-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a D-aminopeptidase from Ochrobactrum anthropi, a new member of the 'penicillin-recognizing enzyme' family. Structure Fold.Des., 8, 2000
1ERM	X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-1-ACETAMIDO-2-(3-CARBOXYPHENYL)ETHANE BORONIC ACID 分子名称: 1(R)-1-ACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID, TEM-1 BETA-LACTAMASE 著者 Ness, S, Martin, R, Kindler, A.M, Paetzel, M, Gold, M, Jones, J.B, Strynadka, N.C.J. 登録日 2000-04-06 公開日 2000-05-10 最終更新日 2012-06-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,). Biochemistry, 39, 2000

 

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