1E25

The high resolution structure of PER-1 class A beta-lactamase

Summary for 1E25

DescriptorEXTENDED-SPECTRUM BETA-LACTAMASE PER-1, SULFATE ION (3 entities in total)
Functional Keywordshydrolase, antibiotic resistance, class a cephalosporinase
Biological sourcePSEUDOMONAS AERUGINOSA
Total number of polymer chains1
Total molecular weight31041.59
Authors
Tranier, S.,Bouthors, A.T.,Maveyraud, L.,Guillet, V.,Sougakoff, W.,Samama, J.P. (deposition date: 2000-05-17, release date: 2000-11-06, Last modification date: 2011-07-13)
Primary citation
Tranier, S.,Bouthors, A.T.,Maveyraud, L.,Guillet, V.,Sougakoff, W.,Samama, J.P.
The High Resolution Crystal Structure for Class a Beta-Lactamase Per-1 Reveals the Bases for its Increase in Breadth of Activity
J.Biol.Chem., 275:28075-, 2000
PubMed: 10825176 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M003802200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.192502.1%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1e25
no rotation
Molmil generated image of 1e25
rotated about x axis by 90°
Molmil generated image of 1e25
rotated about y axis by 90°