1C3B

AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR, BENZO(B)THIOPHENE-2-BORONIC ACID (BZB)

Summary for 1C3B

• Entry DOI: 10.2210/pdb1c3b/pdb
• Related: 2BLS 3BLS
• Descriptor: CEPHALOSPORINASE, BENZO[B]THIOPHENE-2-BORONIC ACID (3 entities in total)
• Functional Keywords: cephalosporinase, beta-lactamase, serine hydrolase, hydrolase
• Biological source: Escherichia coli
• Cellular location: Periplasm: P00811
• Total number of polymer chains: 2
• Total formula weight: 79531.88

Authors

Powers, R.A.,Blazquez, J.,Weston, G.S.,Morosini, M.I.,Baquero, F.,Shoichet, B.K. (deposition date: 1999-07-27, release date: 1999-11-24, Last modification date: 2011-07-13)

• Primary citation: Powers, R.A.,Blazquez, J.,Weston, G.S.,Morosini, M.I.,Baquero, F.,Shoichet, B.K.; The complexed structure and antimicrobial activity of a non-beta-lactam inhibitor of AmpC beta-lactamase.; Protein Sci., 8:2330-2337, 1999; PubMed: 10595535

Experimental method

X-RAY DIFFRACTION (2.25 Å)