8I1U
 
 | | Human TRiC-PhLP2A complex in the closed state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | | Deposit date: | 2023-01-13 | | Release date: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Human TRiC-PhLP2A complex in the closed state
To Be Published
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8I6J
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8G7O
 | | ATP- and mtHsp10-bound mtHsp60 V72I focus | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Braxton, J.R, Shao, H, Tse, E, Gestwicki, J.E, Southworth, D.R. | | Deposit date: | 2023-02-16 | | Release date: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.
Biorxiv, 2023
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8G7N
 | | ATP- and mtHsp10-bound mtHsp60 V72I | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Braxton, J.R, Shao, H, Tse, E, Gestwicki, J.E, Southworth, D.R. | | Deposit date: | 2023-02-16 | | Release date: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.
Biorxiv, 2023
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1SX4
 | | GroEL-GroES-ADP7 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, groEL protein, ... | | Authors: | Chaudhry, C, Horwich, A.L, Brunger, A.T, Adams, P.D. | | Deposit date: | 2004-03-30 | | Release date: | 2005-03-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Exploring the structural dynamics of the E.coli chaperonin GroEL using translation-libration-screw crystallographic refinement of intermediate states.
J.Mol.Biol., 342, 2004
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1SVT
 | | Crystal structure of GroEL14-GroES7-(ADP-AlFx)7 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | Authors: | Chaudhry, C, Horwich, A.L, Brunger, A.T, Adams, P.D. | | Deposit date: | 2004-03-29 | | Release date: | 2005-03-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.808 Å) | | Cite: | Exploring the structural dynamics of the E.coli chaperonin GroEL using translation-libration-screw crystallographic refinement of intermediate states.
J.Mol.Biol., 342, 2004
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1GRU
 | | SOLUTION STRUCTURE OF GROES-ADP7-GROEL-ATP7 COMPLEX BY CRYO-EM | | Descriptor: | GROEL, GROES | | Authors: | Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R. | | Deposit date: | 2001-12-16 | | Release date: | 2002-01-28 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (12.5 Å) | | Cite: | ATP-Bound States of Groel Captured by Cryo-Electron Microscopy.
Cell(Cambridge,Mass.), 107, 2001
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6MRC
 | | ADP-bound human mitochondrial Hsp60-Hsp10 football complex | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Gomez-Llorente, Y, Jebara, F, Patra, M, Malik, R, Nissemblat, S, Azem, A, Hirsch, J.A, Ubarretxena-Belandia, I. | | Deposit date: | 2018-10-12 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin.
Nat Commun, 11, 2020
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1PCQ
 | | Crystal structure of groEL-groES | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | Authors: | Chaudhry, C, Farr, G.W, Todd, M.J, Rye, H.S, Brunger, A.T, Adams, P.D, Horwich, A.L, Sigler, P.B. | | Deposit date: | 2003-05-16 | | Release date: | 2003-10-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.808 Å) | | Cite: | Role of the gamma-phosphate of ATP in triggering protein folding by GroEL-GroES: function, structure and energetics.
Embo J., 22, 2003
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1PF9
 | | GroEL-GroES-ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, groEL protein, ... | | Authors: | Chaudhry, C, Farr, G.W, Todd, M.J, Rye, H.S, Brunger, A.T, Adams, P.D, Horwich, A.L, Sigler, P.B. | | Deposit date: | 2003-05-24 | | Release date: | 2003-11-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.993 Å) | | Cite: | Role of the gamma-phosphate of ATP in triggering protein folding by GroEL-GroES: function, structure and energetics.
Embo J., 22, 2003
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6MRD
 | | ADP-bound human mitochondrial Hsp60-Hsp10 half-football complex | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Gomez-Llorente, Y, Jebara, F, Patra, M, Malik, R, Nissemblat, S, Azem, A, Hirsch, J.A, Ubarretxena-Belandia, I. | | Deposit date: | 2018-10-12 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.82 Å) | | Cite: | Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin.
Nat Commun, 11, 2020
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7WU7
 | | Prefoldin-tubulin-TRiC complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Prefoldin subunit 1, Prefoldin subunit 2, ... | | Authors: | Gestaut, D, Zhao, Y, Park, J, Ma, B, Leitner, A, Collier, M, Pintilie, G, Roh, S.-H, Chiu, W, Frydman, J. | | Deposit date: | 2022-02-07 | | Release date: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (3.85 Å) | | Cite: | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.
Cell, 185, 2022
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8BA9
 | | CryoEM structure of GroEL-GroES-ADP.AlF3-Rubisco. | | Descriptor: | 60 kDa chaperonin, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... | | Authors: | Gardner, S, Saibil, H.R. | | Deposit date: | 2022-10-11 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis of substrate progression through the bacterial chaperonin cycle.
Proc Natl Acad Sci U S A, 120, 2023
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3WVL
 | | Crystal structure of the football-shaped GroEL-GroES complex (GroEL: GroES2:ATP14) from Escherichia coli | | Descriptor: | 10 kDa chaperonin, 60 kDa chaperonin, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Koike-Takeshita, A, Arakawa, T, Taguchi, H, Shimamura, T. | | Deposit date: | 2014-05-23 | | Release date: | 2014-09-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.788 Å) | | Cite: | Crystal structure of a symmetric football-shaped GroEL:GroES2-ATP14 complex determined at 3.8 angstrom reveals rearrangement between two GroEL rings.
J.Mol.Biol., 426, 2014
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3ZPZ
 | | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | | Descriptor: | 10 KDA CHAPERONIN, 60 KDA CHAPERONIN, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Chen, D.-H, Madan, D, Weaver, J, Lin, Z, Schroder, G.F, Chiu, W, Rye, H.S. | | Deposit date: | 2013-03-04 | | Release date: | 2013-06-19 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (8.9 Å) | | Cite: | Visualizing Groel/Es in the Act of Encapsulating a Folding Protein
Cell(Cambridge,Mass.), 153, 2013
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8BMO
 | | Structure of GroEL:GroES complex exhibiting ADP-conformation in trans ring obtained under the continuous turnover conditions | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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8BKZ
 | | GroEL:GroES-ATP complex under continuous turnover conditions | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-09 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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8BM1
 | | Structure of GroEL:GroES-ATP complex under continuous turnover conditions | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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8BM0
 | | Structure of GroEL:GroES-ATP complex plunge frozen 200 ms after reaction initiation | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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8BMT
 | | Structure of GroEL:GroES-ATP complex plunge frozen 200 ms after reaction initiation | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Efremov, R, Torino, S. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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3ZQ1
 | | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | | Descriptor: | 10 KDA CHAPERONIN, 60 KDA CHAPERONIN, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Chen, D.-H, Madan, D, Weaver, J, Lin, Z, Schroder, G.F, Chiu, W, Rye, H.S. | | Deposit date: | 2013-03-04 | | Release date: | 2013-06-19 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (15.9 Å) | | Cite: | Visualizing Groel/Es in the Act of Encapsulating a Folding Protein
Cell(Cambridge,Mass.), 153, 2013
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3ZQ0
 | | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | | Descriptor: | 10 KDA CHAPERONIN, 60 KDA CHAPERONIN, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Chen, D.-H, Madan, D, Weaver, J, Lin, Z, Schroder, G.F, Chiu, W, Rye, H.S. | | Deposit date: | 2013-03-04 | | Release date: | 2013-06-19 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (9.2 Å) | | Cite: | Visualizing Groel/Es in the Act of Encapsulating a Folding Protein
Cell(Cambridge,Mass.), 153, 2013
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8SHE
 | | CCT-G beta 5 complex closed state 8 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | | Deposit date: | 2023-04-13 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
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8SHD
 | | CCT G beta 5 complex closed state 10 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | | Deposit date: | 2023-04-13 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
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8SHP
 | | CCT G beta 5 complex closed state 13 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | | Deposit date: | 2023-04-14 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
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