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4WYR
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Crystal structure of thiolase mutation (V77Q,N153Y,A286K) from Clostridium acetobutylicum
分子名称: Acetyl-CoA acetyltransferase, DI(HYDROXYETHYL)ETHER, GLYCEROL
著者Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
登録日2014-11-18
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
4XL4
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Crystal structure of thiolase from Clostridium acetobutylicum in complex with CoA
分子名称: Acetyl-CoA acetyltransferase, COENZYME A, GLYCEROL
著者Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
登録日2015-01-13
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
4XL2
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Crystal structure of oxidized form of thiolase from Clostridium acetobutylicum
分子名称: ACETATE ION, Acetyl-CoA acetyltransferase, DI(HYDROXYETHYL)ETHER, ...
著者Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
登録日2015-01-13
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
4XL3
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Crystal structure of reduced form of thiolase from Clostridium acetobutylicum
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL
著者Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
登録日2015-01-13
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
2IB9
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BU of 2ib9 by Molmil
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-11
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IBY
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BU of 2iby by Molmil
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IB7
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BU of 2ib7 by Molmil
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-11
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IBU
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Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: Acetyl-CoA acetyltransferase, CHLORIDE ION, COENZYME A, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IBW
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BU of 2ibw by Molmil
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IB8
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BU of 2ib8 by Molmil
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-11
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IIK
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Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
分子名称: 3-ketoacyl-CoA thiolase, peroxisomal
著者Papagrigoriou, E, Johansson, C, Smee, C, Kavanagh, K, Pike, A.C.W, Sundstrom, M, Weigelt, J, Edwards, A, Arrowsmith, C.H, Gileadi, O, Gorrec, F, Umeano, C, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-09-28
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
TO BE PUBLISHED
2VTZ
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Biosynthetic thiolase from Z. ramigera. Complex of the C89A mutant with coenzyme A.
分子名称: ACETYL-COA ACETYLTRANSFERASE, COENZYME A, SULFATE ION
著者Kursula, P, Merilainen, G, Wierenga, R.K.
登録日2008-05-19
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Sulfur Atoms of the Substrate Coa and the Catalytic Cysteine are Required for a Productive Mode of Substrate Binding in Bacterial Biosynthetic Thiolase, a Thioester-Dependent Enzyme.
FEBS J., 275, 2008
2VU1
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Biosynthetic thiolase from Z. ramigera. Complex of with O-pantheteine- 11-pivalate.
分子名称: ACETYL-COA ACETYLTRANSFERASE, PANTOTHENYL-AMINOETHANOL-11-PIVALIC ACID, SODIUM ION, ...
著者Kursula, P, Schmitz, W, Wierenga, R.K.
登録日2008-05-19
公開日2008-10-28
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献The Sulfur Atoms of the Substrate Coa and the Catalytic Cysteine are Required for a Productive Mode of Substrate Binding in Bacterial Biosynthetic Thiolase, a Thioester-Dependent Enzyme.
FEBS J., 275, 2008
2VU0
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Biosynthetic thiolase from Z. ramigera. Complex of the oxidised enzyme with coenzyme A.
分子名称: Acetyl-CoA acetyltransferase, COENZYME A, GLYCEROL, ...
著者Kursula, P, Wierenga, R.K.
登録日2008-05-19
公開日2008-10-28
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme.
FEBS J., 275, 2008
2VU2
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Biosynthetic thiolase from Z. ramigera. Complex with S-pantetheine-11- pivalate.
分子名称: (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate, ACETYL-COA ACETYLTRANSFERASE, SULFATE ION
著者Kursula, P, Merilainen, G, Schmitz, W, Wierenga, R.K.
登録日2008-05-19
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The Sulfur Atoms of the Substrate Coa and the Catalytic Cysteine are Required for a Productive Mode of Substrate Binding in Bacterial Biosynthetic Thiolase, a Thioester-Dependent Enzyme.
FEBS J., 275, 2008
2WKU
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BU of 2wku by Molmil
BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. THE N316H MUTANT.
分子名称: ACETYL-COA ACETYLTRANSFERASE, D-mannose, SULFATE ION
著者Merilainen, G, Poikela, V, Kursula, P, Wierenga, R.K.
登録日2009-06-18
公開日2009-11-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation.
Biochemistry, 48, 2009
2WKT
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BU of 2wkt by Molmil
BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. COMPLEX OF THE N316A MUTANT WITH COENZYME A.
分子名称: ACETYL-COA ACETYLTRANSFERASE, CHLORIDE ION, COENZYME A, ...
著者Merilainen, G, Poikela, V, Kursula, P, Wierenga, R.K.
登録日2009-06-18
公開日2009-11-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation.
Biochemistry, 48, 2009
2WL4
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BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. COMPLEX OF THE H348A MUTANT WITH COENZYME A.
分子名称: ACETYL-COA ACETYLTRANSFERASE, CHLORIDE ION, COENZYME A, ...
著者Merilainen, G, Poikela, V, Kursula, P, Wierenga, R.K.
登録日2009-06-22
公開日2009-11-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation.
Biochemistry, 48, 2009
1M3Z
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BU of 1m3z by Molmil
Biosynthetic thiolase, C89A mutant, complexed with acetyl coenzyme A
分子名称: ACETYL COENZYME *A, Acetyl-CoA acetyltransferase, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-07-03
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1M1T
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BU of 1m1t by Molmil
Biosynthetic thiolase, Q64A mutant
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-06-20
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1M4S
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BU of 1m4s by Molmil
Biosynthetic thiolase, Cys89 acetylated, unliganded form
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-07-03
公開日2002-11-29
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1M1O
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BU of 1m1o by Molmil
Crystal structure of biosynthetic thiolase, C89A mutant, complexed with acetoacetyl-CoA
分子名称: ACETOACETYL-COENZYME A, Acetyl-CoA acetyltransferase, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-06-20
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1M4T
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Biosynthetic thiolase, Cys89 butyrylated
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-07-03
公開日2002-11-29
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1M3K
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BU of 1m3k by Molmil
biosynthetic thiolase, inactive C89A mutant
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-06-28
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1NL7
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BU of 1nl7 by Molmil
Z. ramigera biosynthetic thiolase, acetylated enzyme complexed with CoA at pH 9.5
分子名称: Acetyl-CoA acetyltransferase, COENZYME A, SULFATE ION
著者Kursula, P, Wierenga, R.K.
登録日2003-01-06
公開日2004-04-06
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Crystal structures of Z. ramigera biosynthetic thiolase
To be Published

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