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1PTZ
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Crystal structure of the human CU, Zn Superoxide Dismutase, Familial Amyotrophic Lateral Sclerosis (FALS) Mutant H43R
分子名称: COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者DiDonato, M, Craig, L, Huff, M.E, Thayer, M.M, Cardoso, R.M.F, Kassmann, C.J, Lo, T.P, Bruns, C.K, Powers, E.T, Kelly, J.W, Getzoff, E.D, Tainer, J.A.
登録日2003-06-23
公開日2003-09-09
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献ALS Mutants of Human Superoxide Dismutase Form Fibrous Aggregates Via Framework Destabilization
J.Mol.Biol., 332, 2003
1B4T
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H48C YEAST CU(II)/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE
分子名称: CHLORIDE ION, COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ...
著者Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D.
登録日1998-12-23
公開日1999-12-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
1B4L
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15 ATMOSPHERE OXYGEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE
分子名称: COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ZINC ION
著者Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D.
登録日1998-12-22
公開日1999-12-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
3PU7
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Cu-Zn Tomato Chloroplast Superoxide Dismutase
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], chloroplastic, ...
著者Galaleldeen, A, Taylor, A.B, Hart, P.J.
登録日2010-12-03
公開日2011-12-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biophysical Properties of Tomato Chloroplast SOD
To be Published
2Z7W
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Crystal Structure of H2O2 treated Cu,Zn-SOD
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Ito, S, Ishii, T, Uchida, K.
登録日2007-08-29
公開日2008-09-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of H2O2-treated Cu,Zn-superoxide dismutase
To be Published
8IQ1
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BU of 8iq1 by Molmil
Crystal structure of hydrogen sulfide-bound superoxide dismutase in reduced state
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ...
著者Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C.
登録日2023-03-15
公開日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme.
Cell Rep, 42, 2023
7FB6
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BU of 7fb6 by Molmil
C57D/C146D mutant of Human Cu, Zn Superoxide Dismutase (SOD1)
分子名称: CHLORIDE ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ...
著者Baek, Y, Ha, N.-C.
登録日2021-07-08
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.
Commun Biol, 5, 2022
1S4I
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Crystal structure of a SOD-like protein from Bacillus subtilis
分子名称: CHLORIDE ION, ZINC ION, superoxide dismutase-like protein yojM
著者Banci, L, Bertini, I, Calderone, V, Cramaro, F, Del Conte, R, Fantoni, A, Mangani, S, Quattrone, A, Viezzoli, M.S.
登録日2004-01-16
公開日2005-04-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A prokaryotic superoxide dismutase paralog lacking two Cu ligands: from largely unstructured in solution to ordered in the crystal.
Proc.Natl.Acad.Sci.Usa, 102, 2005
3L9Y
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Crystal structures of holo and Cu-deficient Cu/ZnSOD from the silkworm Bombyx mori and the implications in Amyotrophic lateral sclerosis
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Zhang, N.-N, He, Y.-X, Li, W.-F, Zhao, F, Yan, L.-F, Zhang, G.-Z, Teng, Y.-B, Yu, J, Chen, Y, Zhou, C.-Z.
登録日2010-01-06
公開日2010-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of holo and Cu-deficient Cu/Zn-SOD from the silkworm Bombyx mori and the implications in amyotrophic lateral sclerosis.
Proteins, 78, 2010
1HL5
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The Structure of Holo Type Human Cu, Zn Superoxide Dismutase
分子名称: CALCIUM ION, COPPER (II) ION, SUPEROXIDE DISMUTASE, ...
著者Strange, R.W, Antonyuk, S, Hough, M.A, Doucette, P, Rodriguez, J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2003-03-13
公開日2003-05-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of Holo and Metal-Deficient Wild-Type Human Cu, Zn Superoxide Dismutase and its Relevance to Familial Amyotrophic Lateral Sclerosis
J.Mol.Biol., 328, 2003
2AEO
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BU of 2aeo by Molmil
Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase
分子名称: COPPER (II) ION, Cisplatin, Superoxide dismutase [Cu-Zn], ...
著者Calderone, V, Casini, A, Mangani, S, Messori, L, Orioli, P.L.
登録日2005-07-23
公開日2006-05-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase.
Angew. Chem. Int. Ed. Engl., 45, 2006
3T5W
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BU of 3t5w by Molmil
2ME modified human SOD1
分子名称: COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Ihara, K, Yamaguchi, Y, Torigoe, H, Wakatsuki, S, Taniguchi, N, Suzuki, K, Fujiwara, N.
登録日2011-07-28
公開日2012-08-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural switching of Cu,Zn-superoxide dismutases at loop VI: insights from the crystal structure of 2-mercaptoethanol-modified enzyme
Biosci.Rep., 32, 2012
2AQT
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CU/ZN superoxide dismutase from neisseria meningitidis K91Q, K94Q double mutant
分子名称: COPPER (I) ION, COPPER (II) ION, SULFATE ION, ...
著者DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D.
登録日2005-08-18
公開日2006-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献CU/ZN superoxide dismutase from neisseria meningitidis K91Q, K94Q double mutant
To be Published
1HL4
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BU of 1hl4 by Molmil
The Structure of Apo Type Human Cu, Zn Superoxide Dismutase
分子名称: SUPEROXIDE DISMUTASE, ZINC ION
著者Strange, R.W, Antonyuk, S, Hough, M.A, Doucette, P, Rodriguez, J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2003-03-13
公開日2003-05-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献The Structure of Holo and Metal-Deficient Wild-Type Human Cu, Zn Superoxide Dismutase and its Relevance to Familial Amyotrophic Lateral Sclerosis
J.Mol.Biol., 328, 2003
1E9O
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BU of 1e9o by Molmil
Crystal structure of bovine SOD - 1 of 3
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE
著者Hough, M.A, Samar Hasnain, S.
登録日2000-10-25
公開日2000-12-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conformational Variability of the Cu Site in One Subunit of Bovine Cuzn Superoxide Dismutase: The Importance of Mobility in the Glu119-Leu142 Loop Region for Catalytic Function
J.Mol.Biol., 304, 2000
2Z7Z
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BU of 2z7z by Molmil
Crystal Structure of H2O2 treated Cu,Zn-SOD
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Ito, S, Ishii, T, Uchida, K.
登録日2007-08-30
公開日2008-09-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of H2O2-treated Cu,Zn-superoxide dismutase
To be Published
3H2Q
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BU of 3h2q by Molmil
Human SOD1 H80R variant, P21 crystal form
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J.
登録日2009-04-14
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
3HOG
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BU of 3hog by Molmil
Metal-free Tomato Chloroplast Superoxide Dismutase
分子名称: POTASSIUM ION, Superoxide dismutase [Cu-Zn], chloroplastic
著者Galaleldeen, A, Taylor, A.B, Hart, P.J.
登録日2009-06-02
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Biophysical Properties of Tomato Chloroplast SOD
To be Published
8JD8
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BU of 8jd8 by Molmil
Crystal structure of Citrus limon Cu-Zn superoxide dismutase
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Utami, R.A, Yoshida, H, Retnoningrum, D.S, Ismaya, W.T.
登録日2023-05-12
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Direct relationship between dimeric form and activity in the acidic copper-zinc superoxide dismutase from lemon.
Acta Crystallogr.,Sect.F, 79, 2023
1N19
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BU of 1n19 by Molmil
Structure of the HSOD A4V mutant
分子名称: COPPER (I) ION, SULFATE ION, Superoxide Dismutase [Cu-Zn], ...
著者Cardoso, R.M.F, Thayer, M.M, DiDonato, M, Lo, T.P, Bruns, C.K, Getzoff, E.D, Tainer, J.A.
登録日2002-10-16
公開日2002-11-27
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.
J.Mol.Biol., 324, 2002
8IQ0
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Crystal structure of hydrogen sulfide-bound superoxide dismutase in oxidized state
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ...
著者Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C.
登録日2023-03-15
公開日2023-09-06
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme.
Cell Rep, 42, 2023
1UXM
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BU of 1uxm by Molmil
A4V mutant of human SOD1
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION
著者Hough, M.A, Grossmann, J.G, Antonyuk, S.V, Strange, R.W, Doucette, P.A, Rodriguez, J.A, Whitson, L.J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2004-02-26
公開日2004-03-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dimer Destabilization in Superoxide Dismutase May Result in Disease-Causing Properties: Structures of Motor Neuron Disease Mutants
Proc.Natl.Acad.Sci.USA, 101, 2004
3CQQ
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Human SOD1 G85R Variant, Structure II
分子名称: ACETYL GROUP, Superoxide dismutase [Cu-Zn], ZINC ION
著者Cao, X, Antonyuk, S, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J.
登録日2008-04-03
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
1AZV
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FAMILIAL ALS MUTANT G37R CUZNSOD (HUMAN)
分子名称: COPPER (II) ION, COPPER/ZINC SUPEROXIDE DISMUTASE, ZINC ION
著者Hart, P.J, Liu, H, Pellegrini, M, Nersissian, A.M, Gralla, E.B, Valentine, J.S, Eisenberg, D.
登録日1997-11-21
公開日1998-02-25
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis.
Protein Sci., 7, 1998
5YTU
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Structure of human SOD1 complexed with isoproteranol in C2221 space group
分子名称: Dihydrogen tetrasulfide, GLYCEROL, ISOPRENALINE, ...
著者Manjula, R, Padmanabhan, B.
登録日2017-11-20
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Assessment of ligand binding at a site relevant to SOD1 oxidation and aggregation
FEBS Lett., 592, 2018

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