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1Z9N
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BU of 1z9n by Molmil
X-Ray structure of a Cu-Zn superoxide dismutase from Haemophilus ducreyi with haem bound at the dimer interface
分子名称: COPPER (II) ION, PROTOPORPHYRIN IX CONTAINING FE, Superoxide dismutase [Cu-Zn], ...
著者Djinovic Carugo, K, Toeroe, I.
登録日2005-04-03
公開日2006-09-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of heme binding in the Cu,Zn superoxide dismutase from Haemophilus ducreyi.
J.Mol.Biol., 386, 2009
1Z9P
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X-Ray structure of a Cu-Zn superoxide dismutase from Haemophilus ducreyi
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Djinovic Carugo, K, Toeroe, I.
登録日2005-04-04
公開日2006-09-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of heme binding in the Cu,Zn superoxide dismutase from Haemophilus ducreyi.
J.Mol.Biol., 386, 2009
1OAL
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BU of 1oal by Molmil
Active site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE, ZINC ION
著者Cioni, P, Pesce, A, Rocca, B.M.D, Castellifalconiparrilli, L, Bolognesi, M, Strambini, G, Desideri, A.
登録日2003-01-15
公開日2003-02-27
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Active-Site Copper and Zinc Ions Modulate the Quaternary Structure of Prokaryotic Cu,Zn Superoxide Dismutase
J.Mol.Biol., 326, 2003
2WZ6
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BU of 2wz6 by Molmil
G93A SOD1 mutant complexed with Quinazoline.
分子名称: 4-(4-METHYL-1,4-DIAZEPAN-1-YL)-2-(TRIFLUOROMETHYL)QUINAZOLINE, COPPER (II) ION, SULFATE ION, ...
著者Antonyuk, S.V, Strange, R.W, Hasnain, S.S.
登録日2009-11-23
公開日2010-12-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization.
J.Med.Chem., 53, 2010
2XJL
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BU of 2xjl by Molmil
Monomeric Human Cu,Zn Superoxide dismutase without Cu ligands
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ...
著者Saraboji, K, Leinartaite, L, Nordlund, A, Oliveberg, M, Logan, D.T.
登録日2010-07-07
公開日2010-09-01
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the Als-Associated Enzyme Cu/Zn Superoxide Dismutase 1.
J.Am.Chem.Soc., 132, 2010
2Z7Y
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BU of 2z7y by Molmil
Crystal Structure of H2O2 treated Cu,Zn-SOD
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Ito, S, Ishii, T, Uchida, K.
登録日2007-08-30
公開日2008-09-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of H2O2-treated Cu,Zn-superoxide dismutase
To be Published
6Z4J
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BU of 6z4j by Molmil
A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 5 in P21 space group
分子名称: CHLORIDE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
6Z4M
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BU of 6z4m by Molmil
A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 10 in P21 space group
分子名称: CHLORIDE ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
5IN2
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BU of 5in2 by Molmil
Crystal structure of extra cellular Cu/Zn Superoxide Dismutase from Onchocerca volvulus at 1.5 Angstrom; Insight into novel binding site and new inhibitors
分子名称: AZIDE ION, CHLORIDE ION, COPPER (II) ION, ...
著者Moustafa, A, Betzel, C, Perbandt, M.
登録日2016-03-07
公開日2017-03-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of extracellular Cu/Zn Superoxide Dismutase from Onchocerca volvulus at 1.5 Angstrom; Insight into novel binding site and new inhibitors
To Be Published
6FN8
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BU of 6fn8 by Molmil
Domain II of the HUMAN COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE at 1.55 A resolution
分子名称: Copper chaperone for superoxide dismutase, ZINC ION
著者Sala, F.A, Wright, G.S.A, Antonyuk, S.V, Garratt, R.C, Hasnain, S.S.
登録日2018-02-02
公開日2019-01-30
最終更新日2019-06-19
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS.
Plos Biol., 17, 2019
3H2P
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BU of 3h2p by Molmil
Human SOD1 D124V Variant
分子名称: ACETYL GROUP, MALONATE ION, Superoxide dismutase [Cu-Zn], ...
著者Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J.
登録日2009-04-14
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
1JCV
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BU of 1jcv by Molmil
REDUCED BRIDGE-BROKEN YEAST CU/ZN SUPEROXIDE DISMUTASE LOW TEMPERATURE (-180C) STRUCTURE
分子名称: COPPER (II) ION, CU/ZN SUPEROXIDE DISMUTASE, ZINC ION
著者Ogihara, N.L, Parge, H.E, Hart, P.J, Weiss, M.S, Valentine, J.S, Eisenberg, D.S, Tainer, J.A.
登録日1995-12-07
公開日1996-03-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Unusual trigonal-planar copper configuration revealed in the atomic structure of yeast copper-zinc superoxide dismutase.
Biochemistry, 35, 1996
1TO4
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BU of 1to4 by Molmil
Structure of the cytosolic Cu,Zn SOD from S. mansoni
分子名称: COPPER (II) ION, Superoxide dismutase, ZINC ION
著者Cardoso, R.M.F, Silva, C.H.T.P, Ulian de Araujo, A.P, Tanaka, T, Tanaka, M, Garratt, R.C.
登録日2004-06-12
公開日2004-08-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of the cytosolic Cu,Zn superoxide dismutase from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 60, 2004
6ZS1
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BU of 6zs1 by Molmil
Chaetomium thermophilum CuZn-superoxide dismutase
分子名称: COPPER (II) ION, GLYCEROL, PHOSPHATE ION, ...
著者Papageorgiou, A.C, Mohsin, I.
登録日2020-07-15
公開日2021-04-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Crystal Structure of a Cu,Zn Superoxide Dismutase From the Thermophilic Fungus Chaetomium thermophilum.
Protein Pept.Lett., 28, 2021
2VR7
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BU of 2vr7 by Molmil
Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.58 A resolution
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J.
登録日2008-03-28
公開日2008-04-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
1UXL
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BU of 1uxl by Molmil
I113T mutant of human SOD1
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Hough, M.A, Grossmann, J.G, Antonyuk, S.V, Strange, R.W, Doucette, P.A, Rodriguez, J.A, Whitson, L.J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2004-02-25
公開日2004-03-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Dimer Destabilization in Superoxide Dismutase May Result in Disease-Causing Properties: Structures of Motor Neuron Disease Mutants
Proc.Natl.Acad.Sci.USA, 101, 2004
6D52
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BU of 6d52 by Molmil
Superoxide dismutase SodCI of Salmonella enterica serovar Typhimurium at 1.6 Angstrom resolution
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn] 1, ZINC ION
著者Newhouse IX, P.W, Forest, K.T, Satyshur, K.A.
登録日2018-04-19
公開日2019-05-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Superoxide dismutase SodCI of Salmonella enterica serovar Typhimurium at 1.6 Angstrom resolution
to be published
1XTM
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BU of 1xtm by Molmil
Crystal structure of the double mutant Y88H-P104H of a SOD-like protein from Bacillus subtilis.
分子名称: COPPER (II) ION, Hypothetical superoxide dismutase-like protein yojM, ZINC ION
著者Calderone, V, Mangani, S, Banci, L, Benvenuti, M, Bertini, I, Fantoni, A, Viezzoli, M.S.
登録日2004-10-22
公開日2005-10-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献From an Inactive Prokaryotic SOD Homologue to an Active Protein through Site-Directed Mutagenesis.
J.Am.Chem.Soc., 127, 2005
7WWT
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BU of 7wwt by Molmil
Cu/Zn-superoxide dismutase from dog (Canis familiaris)
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Narikiyo, S, Furukawa, Y, Akutsu, M.
登録日2022-02-14
公開日2023-02-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy-linked E40K mutation.
J.Biol.Chem., 299, 2023
6Z4L
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BU of 6z4l by Molmil
A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 9 in P21 space group
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
6Z4I
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BU of 6z4i by Molmil
A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 3 in P21 space group
分子名称: ACETATE ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
5J0C
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BU of 5j0c by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P2/3
分子名称: Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn]
著者Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M.
登録日2016-03-28
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
1PZS
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BU of 1pzs by Molmil
Crystal Structure of a Cu-Zn Superoxide Dismutase from Mycobacterium tuberculosis at 1.63 resolution
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn]
著者Djinovic-Carugo, K, Spagnolo, L, Toro, I.
登録日2003-07-14
公開日2004-07-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Unique Features of the sodC-encoded Superoxide Dismutase from Mycobacterium tuberculosis, a Fully Functional Copper-containing Enzyme Lacking Zinc in the Active Site.
J.Biol.Chem., 279, 2004
2AQQ
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BU of 2aqq by Molmil
CU/ZN superoxid dismutate from neisseria meningitidis K91E mutant
分子名称: COPPER (I) ION, COPPER (II) ION, SULFATE ION, ...
著者DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D.
登録日2005-08-18
公開日2006-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献CU/ZN superoxid dismutate from neisseria meningitidis K91E mutant
To be Published
7WX1
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BU of 7wx1 by Molmil
E40K/M117L variant of Cu/Zn-superoxide dismutase from dog (Canis familiaris)
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Narikiyo, S, Furukawa, Y, Akutsu, M.
登録日2022-02-14
公開日2023-02-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy-linked E40K mutation.
J.Biol.Chem., 299, 2023

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