PDB: 255 件ウェブページステータス検索Chemie searchBIRD

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3F5N	Structure of native human neuroserpin 分子名称: Neuroserpin 著者 Ricagno, S, Caccia, S, Sorrentino, G, Bolognesi, M. 登録日 2008-11-04 公開日 2009-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Human neuroserpin: structure and time-dependent inhibition J.Mol.Biol., 388, 2009
5OM3	Crystal structure of Alpha1-antichymotrypsin variant DBS-I5: a MMP14-cleavable drug-binding serpin for doxycycline 分子名称: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, Alpha-1-antichymotrypsin, DI(HYDROXYETHYL)ETHER 著者 Schmidt, K, Muller, Y.A. 登録日 2017-07-28 公開日 2018-05-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3FGQ	Crystal structure of native human neuroserpin 分子名称: GLYCEROL, Neuroserpin 著者 Takehara, S, Yang, X, Mikami, B, Onda, M. 登録日 2008-12-08 公開日 2009-04-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability J.Mol.Biol., 388, 2009
3ZHA	Molecular basis for the action of the collagen-specific chaperone Hsp47 SERPINH1 and its structure-specific client recognition. 分子名称: COLLAGEN MODEL PEPTIDE 18-T8R11, HSP47, SUCCINIC ACID 著者 Widmer, C, Gebauer, J.M, Baumann, U. 登録日 2012-12-20 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
4AQH	Plasminogen activator inhibitor type-1 in complex with the inhibitor AZ3976 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR 1, TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE 著者 Fjellstrom, O, Deinum, J, Sjogren, T, Johansson, C, Geschwindner, S, Nerme, V, Legnehed, A, McPheat, J, Olsson, K, Bodin, C, Gustafsson, D. 登録日 2012-04-17 公開日 2012-11-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 that Accelerates the Transition Into the Latent Conformation J.Biol.Chem., 288, 2013
4AJT	The crystal structure of mouse protein-Z dependent protease inhibitor(mZPI) 分子名称: PROTEIN Z-DEPENDENT PROTEASE INHIBITOR 著者 Yan, Y, Zhou, A. 登録日 2012-02-19 公開日 2012-12-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
4AJU	Crystal structure of the reactive loop cleaved ZPI in P41 space group 分子名称: 1,2-ETHANEDIOL, PROTEIN Z-DEPENDENT PROTEASE INHIBITOR, SULFATE ION 著者 Zhou, A, Yan, Y, Wei, Z. 登録日 2012-02-19 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
4AFX	Crystal structure of the reactive loop cleaved ZPI in I2 space group 分子名称: CALCIUM ION, PHOSPHATE ION, PROTEIN Z DEPENDENT PROTEASE INHIBITOR, ... 著者 Zhou, A, Yan, Y, Wei, Z. 登録日 2012-01-23 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
4AU4	Crystal Structure of Hsp47 分子名称: SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), MEMBER 1, ... 著者 Widmer, C, Gebauer, J.M, Brunstein, E, Rodenbaum, S, Zaucke, F, Drogemuller, C, Leeb, T, Baumann, U. 登録日 2012-05-14 公開日 2012-08-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
4AU2	Crystal Structure of a Hsp47-collagen complex 分子名称: 15ER COLLAGEN MODEL PEPTIDE 15-R8, SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), ... 著者 Widmer, C, Gebauer, J.M, Brunstein, E, Drogemuller, C, Leeb, T, Baumann, U. 登録日 2012-05-13 公開日 2012-08-15 最終更新日 2015-04-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
4BB2	Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone 分子名称: 1,2-ETHANEDIOL, CORTICOSTEROID-BINDING GLOBULIN, CYSTEINE, ... 著者 Gardill, B.R, Vogl, M.R, Lin, H, Hammond, G.L, Muller, Y.A. 登録日 2012-09-19 公開日 2012-12-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences Plos One, 7, 2012
4C49	Reactive loop cleaved human CBG in complex with cortisol 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN 著者 Chan, W.L, Zhou, A, Read, R.J. 登録日 2013-09-02 公開日 2014-10-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Role of Sa-Hd Loop Movement in Cortisol Release Mechanism of Cbg To be Published
4C41	Corticosteroid-binding globulin with engineered disulphide bridge between residues 100 and 236 分子名称: CORTICOSTEROID-BINDING GLOBULIN 著者 Chan, W.L, Zhou, A, Read, R.J. 登録日 2013-08-28 公開日 2014-10-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Towards Engineering Hormone-Binding Globulins as Drug Delivery Agents. Plos One, 9, 2014
4CAA	CLEAVED ANTICHYMOTRYPSIN T345R 分子名称: ANTICHYMOTRYPSIN 著者 Lukacs, C.M, Christianson, D.W. 登録日 1997-08-14 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
1WZ9	The 2.1 A structure of a tumour suppressing serpin 分子名称: Maspin precursor, SULFATE ION 著者 Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. 登録日 2005-03-03 公開日 2005-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
1LQ8	Crystal structure of cleaved protein C inhibitor 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Huntington, J.A, Kjellberg, M, Stenflo, J. 登録日 2002-05-09 公開日 2003-02-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Protein C Inhibitor Provides Insights into Hormone Binding and Heparin Activation Structure, 11, 2003
1LK6	Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Zhou, A, Huntington, J.A, Lomas, D.A, Carrell, R.W, Stein, P.E. 登録日 2002-04-24 公開日 2003-06-03 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Serpin Polymerization Is Prevented by a Hydrogen Bond Network That Is Centered on His-334 and Stabilized by Glycerol J.Biol.Chem., 278, 2003
1LJ5	1.8A Resolution Structure of Latent Plasminogen Activator Inhibitor-1(PAI-1) 分子名称: ACETIC ACID, DIMETHYL SULFOXIDE, PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Stein, P.E, Baek, K. 登録日 2002-04-19 公開日 2002-05-08 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献
1XU8	The 2.8 A structure of a tumour suppressing serpin 分子名称: Maspin, SULFATE ION 著者 Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C. 登録日 2004-10-25 公開日 2005-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
1XQG	3.10 A crystal structure of maspin, Space group P 4 21 2 分子名称: Maspin 著者 Al-Ayyoubi, M, Gettins, P.G, Volz, K. 登録日 2004-10-12 公開日 2004-10-26 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained J.Biol.Chem., 279, 2004
1XQJ	3.10 A Crystal structure of maspin, space group I 4 2 2 分子名称: Maspin 著者 Al-Ayyoubi, M, Gettins, P.G, Volz, K. 登録日 2004-10-12 公開日 2004-10-26 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained J.Biol.Chem., 279, 2004
1M93	1.65 A Structure of Cleaved Viral Serpin CRMA 分子名称: PHOSPHATE ION, Serine proteinase inhibitor 2 著者 Simonovic, M, Gettins, P.G.W, Volz, K. 登録日 2002-07-26 公開日 2003-08-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition Protein Sci., 9, 2000
1MTP	The X-ray crystal structure of a serpin from a thermophilic prokaryote 分子名称: Serine Proteinase Inhibitor (SERPIN), Chain A, Chain B 著者 Irving, J.A, Cabrita, L.D, Rossjohn, J, Pike, R.N, Bottomley, S.P, Whisstock, J.C. 登録日 2002-09-21 公開日 2003-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment Structure, 11, 2003
1NQ9	Crystal Structure of Antithrombin in the Pentasaccharide-Bound Intermediate State 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ... 著者 Huntington, J.A, Johnson, D.J.D. 登録日 2003-01-21 公開日 2003-09-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Antithrombin in a Heparin-Bound Intermediate State Biochemistry, 42, 2003
1YXA	Serpina3n, a murine orthologue of human antichymotrypsin 分子名称: serine (or cysteine) proteinase inhibitor, clade A, member 3N 著者 Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C. 登録日 2005-02-20 公開日 2005-09-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins. J.Biol.Chem., 280, 2005

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