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7AHP
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Crystal structure of Ixodes ricinus serpin - Iripin-3
分子名称: Putative salivary serpin, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM
著者Kascakova, B, Kuta Smatanova, I, Prudnikova, T.
登録日2020-09-25
公開日2021-03-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Iripin-3, a New Salivary Protein Isolated From Ixodes ricinus Ticks, Displays Immunomodulatory and Anti-Hemostatic Properties In Vitro
Front Immunol, 12, 2021
7B2T
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Crystal structure of Iripin-5 serpin from Ixodes ricinus
分子名称: CHLORIDE ION, MAGNESIUM ION, Serpin-4 precursor, ...
著者Kascakova, B, Kuta Smatanova, I.
登録日2020-11-27
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and biochemical characterization of the novel serpin Iripin-5 from Ixodes ricinus.
Acta Crystallogr D Struct Biol, 77, 2021
4G8R
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Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1
分子名称: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION
著者Stuckey, J.A, Lawrence, D.A, Li, S.-H.
登録日2012-07-23
公開日2013-12-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4R9I
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Crystal structure of cysteine proteinase inhibitor Serpin18 from Bombyx mori
分子名称: BETA-MERCAPTOETHANOL, CITRATE ANION, SODIUM ION, ...
著者Guo, P.C, He, H.W, Zhao, P, Xia, Q.Y.
登録日2014-09-05
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18
Sci Rep, 5, 2015
4G8O
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Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1
分子名称: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), 1,2-ETHANEDIOL, Plasminogen activator inhibitor 1, ...
著者Stuckey, J.A, Lawrence, D.A, Li, S.-H.
登録日2012-07-23
公開日2013-12-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GA7
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Crystal structure of human serpinB1 mutant
分子名称: Leukocyte elastase inhibitor
著者Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z.
登録日2012-07-25
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
4RSQ
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2.9A resolution structure of SRPN2 (K198C/E359C) from Anopheles gambiae
分子名称: Serpin 2
著者Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K.
登録日2014-11-10
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
4ROA
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1.90A resolution structure of SRPN2 (S358W) from Anopheles gambiae
分子名称: Serpin 2
著者Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K.
登録日2014-10-28
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
4RO9
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2.0A resolution structure of SRPN2 (S358E) from Anopheles gambiae
分子名称: GLYCEROL, Serpin 2
著者Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K.
登録日2014-10-28
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
4ROB
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2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae
分子名称: Serpin 2
著者Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K.
登録日2014-10-28
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae
To be Published
4IC0
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Crystal Structure of PAI-1 in Complex with Gallate
分子名称: 3,4,5-trihydroxybenzoic acid, Plasminogen activator inhibitor 1
著者Hong, Z.B, Lin, Z.H, Gong, L.H, Huang, M.D.
登録日2012-12-09
公開日2013-12-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal Structure of PAI-1 in Complex with Gallate
To be Published
2CEO
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thyroxine-binding globulin complex with thyroxine
分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, GLYCEROL, THYROXINE-BINDING GLOBULIN
著者Zhou, A, Wei, Z, Read, R.J, Carrell, R.W.
登録日2006-02-08
公開日2006-08-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Mechanism for the Carriage and Release of Thyroxine in the Blood.
Proc.Natl.Acad.Sci.USA, 103, 2006
2DUT
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Crystal structure of a M-loop deletion variant of MENT in the native conformation
分子名称: Heterochromatin-associated protein MENT
著者Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A.
登録日2006-07-26
公開日2006-08-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation
Embo J., 25, 2006
3LE2
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BU of 3le2 by Molmil
Structure of Arabidopsis AtSerpin1. Native Stressed Conformation
分子名称: ACETATE ION, GLYCEROL, SULFATE ION, ...
著者Harrop, S.J, Joss, T.V, Cumi, P.M.G, Roberts, T.H.
登録日2010-01-14
公開日2010-02-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Arabidopsis AtSerpin1, crystal structure and in vivo interaction with its target protease RESPONSIVE TO DESICCATION-21 (RD21).
J.Biol.Chem., 285, 2010
3LW2
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Mouse Plasminogen Activator Inhibitor-1 (PAI-1)
分子名称: Plasminogen activator inhibitor 1
著者Dewilde, M, Van De Craen, B, Compernolle, G, Madsen, J.B, Strelkov, S.V, Gils, A, Declerck, P.J.
登録日2010-02-23
公開日2010-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Subtle structural differences between human and mouse PAI-1 reveal the basis for biochemical differences.
J.Struct.Biol., 171, 2010
3NDA
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Crystal structure of serpin from tick Ixodes ricinus
分子名称: PENTAETHYLENE GLYCOL, Serpin-2
著者Rezacova, P, Kovarova, Z, Chmelar, J, Mares, M.
登録日2010-06-07
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation.
Blood, 117, 2011
3NE4
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1.8 Angstrom structure of intact native wild-type alpha-1-antitrypsin
分子名称: Alpha-1-antitrypsin
著者Patschull, A.O.M, Gooptu, B, Segu, L.
登録日2010-06-08
公開日2011-12-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Therapeutic target-site variability in [alpha]1-antitrypsin characterized at high resolution
Acta Crystallogr.,Sect.F, 67, 2011
3NDF
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Cleaved antitrypsin with P8-P6 Asp
分子名称: Alpha-1-antitrypsin
著者Huntington, J.A, Sendall, T.J, Yamasaki, M.
登録日2010-06-07
公開日2010-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Loop-sheet mechanism of serpin polymerization tested by reactive center loop mutations
J. Biol. Chem., 285, 2010
3NDD
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Cleaved antitrypsin with P10 Pro, and P9-P6 Asp
分子名称: Alpha-1-antitrypsin
著者Yamasaki, M, Sendall, T.J, Huntington, J.A.
登録日2010-06-07
公開日2010-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Loop-sheet mechanism of serpin polymerization tested by reactive center loop mutations
J. Biol. Chem., 285, 2010
2H4R
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Crystal structure of wildtype MENT in the native conformation
分子名称: Heterochromatin-associated protein MENT
著者Irving, J.A, Whisstock, J.C, Buckle, A.M, McGowan, S.
登録日2006-05-25
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
2H4Q
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Crystal structure of a M-loop deletion variant of MENT in the cleaved conformation
分子名称: Heterochromatin-associated protein MENT
著者Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A.
登録日2006-05-25
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
2H4P
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Crystal structure of wildtype MENT in the cleaved conformation
分子名称: Heterochromatin-associated protein MENT
著者Buckle, A.M, McGowan, S, Irving, J.A, Whisstock, J.C.
登録日2006-05-24
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
2HI9
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Crystal Structure of human native protein C inhibitor
分子名称: CITRIC ACID, GLYCEROL, Plasma serine protease inhibitor
著者Li, W, Adams, T.E, Huntington, J.A.
登録日2006-06-29
公開日2007-03-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of native protein C inhibitor provides insight into its multiple functions.
J.Biol.Chem., 282, 2007
2HIJ
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Crystal Structure of P14 Alanine Variant of Antithrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ...
著者Luis, S.A, Bock, S.C, Huntington, J.A.
登録日2006-06-29
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of P14 Alanine Variant of Antithrombin
To be Published
3OZQ
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Crystal structure of Serpin48, which is a highly specific serpin in the insect Tenebrio molitor
分子名称: Serpin48
著者Park, S.H, Piao, S, Ha, N.-C.
登録日2010-09-27
公開日2010-10-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional characterization of a highly specific serpin in the insect innate immunity
J.Biol.Chem., 286, 2011

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