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5OBN
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BU of 5obn by Molmil
NMR solution structure of U11/U12 65K protein's C-terminal RRM domain (381-516)
Descriptor: RNA-binding protein 40
Authors:Norppa, A.J, Kauppala, T.M, Heikkinen, H.A, Verma, B, Iwai, H, Frilander, M.J.
Deposit date:2017-06-28
Release date:2018-01-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA.
RNA, 24, 2018
5O9Z
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BU of 5o9z by Molmil
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ...
Authors:Bertram, K, Kastner, B.
Deposit date:2017-06-20
Release date:2017-08-16
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell, 170, 2017
5O3J
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BU of 5o3j by Molmil
Crystal structure of TIA-1 RRM2 in complex with RNA
Descriptor: Nucleolysin TIA-1 isoform p40, RNA (5'-R(P*UP*UP*C)-3')
Authors:Sonntag, M, Jagtap, P.K.A, Hennig, J, Sattler, M.
Deposit date:2017-05-24
Release date:2017-07-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins.
Angew. Chem. Int. Ed. Engl., 56, 2017
5O2V
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BU of 5o2v by Molmil
NMR structure of TIA-1 RRM1 domain
Descriptor: Nucleolysin TIA-1 isoform p40
Authors:Jagtap, P.K.A.
Deposit date:2017-05-22
Release date:2017-06-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins.
Angew. Chem. Int. Ed. Engl., 56, 2017
5O20
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BU of 5o20 by Molmil
Structure of Nrd1 RNA binding domain in complex with RNA (UUAGUAAUCC)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Protein NRD1, RNA (5'-R(*UP*AP*GP*UP*AP*AP*UP*C)-3')
Authors:Franco-Echevarria, E, Perez-Canadillas, J.M, Gonzalez, B.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.53 Å)
Cite:The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O1Z
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BU of 5o1z by Molmil
Structure of Nrd1 RNA binding domain in complex with RNA (CGUAAA)
Descriptor: Protein NRD1, RNA (5'-R(*CP*GP*UP*AP*AP*A)-3')
Authors:Franco-Echevarria, E, Perez-Canadillas, J.M, Gonzalez, B.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O1Y
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BU of 5o1y by Molmil
Structure of Nrd1 RNA binding domain in complex with RNA (GUAA)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Protein NRD1, ...
Authors:Franco-Echevarria, E, Perez-Canadillas, J.M, Gonzalez, B.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O1X
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BU of 5o1x by Molmil
Structure of Nrd1 RNA binding domain
Descriptor: 1,2-ETHANEDIOL, Protein NRD1, THIOCYANATE ION
Authors:Franco-Echevarria, E, Perez-Canadillas, J.M, Gonzalez, B.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O1W
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BU of 5o1w by Molmil
Structure of Nrd1 RNA binding domain
Descriptor: 1,2-ETHANEDIOL, Protein NRD1
Authors:Franco-Echevarria, E, Perez-Canadillas, J.M, Gonzalez, B.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O1T
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BU of 5o1t by Molmil
Solution structure of the RNA binding domain of Nrd1
Descriptor: Protein NRD1
Authors:Martinez-Lumbreras, S, Perez-Canadillas, J.M.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5NRL
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BU of 5nrl by Molmil
Structure of a pre-catalytic spliceosome.
Descriptor: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ...
Authors:Plaschka, C, Lin, P.-C, Nagai, K.
Deposit date:2017-04-24
Release date:2017-05-31
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structure of a pre-catalytic spliceosome.
Nature, 546, 2017
5MQF
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BU of 5mqf by Molmil
Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ...
Authors:Bertram, K, Hartmuth, K, Kastner, B.
Deposit date:2016-12-20
Release date:2017-03-22
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature, 542, 2017
5MQ0
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BU of 5mq0 by Molmil
Structure of a spliceosome remodeled for exon ligation
Descriptor: 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ...
Authors:Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5MPS
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BU of 5mps by Molmil
Structure of a spliceosome remodeled for exon ligation
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
Deposit date:2016-12-18
Release date:2017-01-18
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5MPL
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BU of 5mpl by Molmil
hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, RNA UCAGUU
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2016-12-16
Release date:2017-07-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017
5MPG
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BU of 5mpg by Molmil
Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, RNA UUAGGUC
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2016-12-16
Release date:2017-07-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017
5MMM
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BU of 5mmm by Molmil
Structure of the 70S chloroplast ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein 2, ...
Authors:Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N.
Deposit date:2016-12-11
Release date:2017-01-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The complete structure of the chloroplast 70S ribosome in complex with translation factor pY.
EMBO J., 36, 2017
5MMJ
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BU of 5mmj by Molmil
Structure of the small subunit of the chloroplast ribosome
Descriptor: 16S ribosomal RNA, 30S ribosomal protein 2, chloroplastic, ...
Authors:Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N.
Deposit date:2016-12-10
Release date:2017-01-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The complete structure of the chloroplast 70S ribosome in complex with translation factor pY.
EMBO J., 36, 2017
5MDU
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BU of 5mdu by Molmil
Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe.
Descriptor: CHLORIDE ION, GLYCEROL, Rpb7-binding protein seb1, ...
Authors:Wittmann, S, Renner, M, El Omari, K, Adams, O, Vasiljeva, L, Grimes, J.
Deposit date:2016-11-13
Release date:2017-04-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA.
Nat Commun, 8, 2017
5M8I
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BU of 5m8i by Molmil
Solution structure of CUG-BP2 RRM3 in complex with 5'-UUUAA-3' RNA
Descriptor: CUGBP Elav-like family member 2, RNA (5'-R(*UP*UP*UP*AP*A)-3')
Authors:Diarra dit Konte, N, Damberger, F.F, Allain, F.H.T.
Deposit date:2016-10-28
Release date:2017-10-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Aromatic side-chain conformational switch on the surface of the RNA Recognition Motif enables RNA discrimination.
Nat Commun, 8, 2017
5LXY
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BU of 5lxy by Molmil
Structure of the minimal RBM7 - ZCCHC8 Complex
Descriptor: BROMIDE ION, RNA-binding protein 7, Zinc finger CCHC domain-containing protein 8
Authors:Falk, S, Finogenova, K, Benda, C, Conti, E.
Deposit date:2016-09-23
Release date:2016-12-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
5LXR
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BU of 5lxr by Molmil
Structure of the minimal RBM7 - ZCCHC8 Complex
Descriptor: BROMIDE ION, CHLORIDE ION, RNA-binding protein 7, ...
Authors:Falk, S, Finogenova, K, Benda, C, Conti, E.
Deposit date:2016-09-22
Release date:2016-12-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
5LSO
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BU of 5lso by Molmil
Crystal structure of SPF45 UHM domain with cyclic peptide inhibitor
Descriptor: LYS-SER-ARG-TRP-ASP-GLU, Splicing factor 45
Authors:Jagtap, P.K.A, Garg, D, Sattler, M.
Deposit date:2016-09-05
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
J. Med. Chem., 59, 2016
5LSL
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BU of 5lsl by Molmil
Crystal structure of yeast Hsh49p in complex with Cus1p binding domain.
Descriptor: Cold sensitive U2 snRNA suppressor 1, Protein HSH49
Authors:van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K.
Deposit date:2016-09-02
Release date:2017-04-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.
RNA, 23, 2017
5LSB
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BU of 5lsb by Molmil
Crystal structure of yeast Hsh49p in complex with Cus1p binding domain.
Descriptor: Cold sensitive U2 snRNA suppressor 1, Protein HSH49
Authors:van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K.
Deposit date:2016-08-24
Release date:2017-04-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.
RNA, 23, 2017

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