1FE5
 
 | | SEQUENCE AND CRYSTAL STRUCTURE OF A BASIC PHOSPHOLIPASE A2 FROM COMMON KRAIT (BUNGARUS CAERULEUS) AT 2.4 RESOLUTION: IDENTIFICATION AND CHARACTERIZATION OF ITS PHARMACOLOGICAL SITES. | | 分子名称: | CALCIUM ION, PHOSPHOLIPASE A2 | | 著者 | Singh, G, Gourinath, S, Sharma, S, Paramasivam, M, Srinivasan, A, Singh, T.P. | | 登録日 | 2000-07-21 | | 公開日 | 2001-01-24 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Sequence and crystal structure determination of a basic phospholipase A2 from common krait (Bungarus caeruleus) at 2.4 A resolution: identification and characterization of its pharmacological sites.
J.Mol.Biol., 307, 2001
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1FV0
 | | FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 9-HYDROXY ARISTOLOCHIC ACID, ACETATE ION, ... | | 著者 | Chandra, V, Jasti, J, Kaur, P, Srinivasan, A, Betzel, C, Singh, T.P. | | 登録日 | 2000-09-18 | | 公開日 | 2002-08-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Basis of Phospholipase A2 Inhibition for the Synthesis of Prostaglandins by the Plant Alkaloid Aristolochic Acid from a 1.7 A Crystal Structure
Biochemistry, 41, 2002
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1FX9
 | | CARBOXYLIC ESTER HYDROLASE COMPLEX (DIMERIC PLA2 + MJ33 INHIBITOR + SULPHATE IONS) | | 分子名称: | 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PHOSPHOLIPASE A2, ... | | 著者 | Pan, Y.H, Epstein, T.M, Jain, M.K, Bahnson, B.J. | | 登録日 | 2000-09-25 | | 公開日 | 2001-09-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Five coplanar anion binding sites on one face of phospholipase A2: relationship to interface binding.
Biochemistry, 40, 2001
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1FXF
 | | CARBOXYLIC ESTER HYDROLASE COMPLEX (DIMERIC PLA2 + MJ33 INHIBITOR + PHOSPHATE IONS) | | 分子名称: | 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PHOSPHATE ION, ... | | 著者 | Pan, Y.H, Epstein, T.M, Jain, M.K, Bahnson, B.J. | | 登録日 | 2000-09-25 | | 公開日 | 2001-09-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Five coplanar anion binding sites on one face of phospholipase A2: relationship to interface binding.
Biochemistry, 40, 2001
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1G0Z
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1G2X
 | | Sequence induced trimerization of krait PLA2: crystal structure of the trimeric form of krait PLA2 | | 分子名称: | PHOSPHOLIPASE A2 | | 著者 | Singh, G, Gourinath, S, Sharma, S, Bhanumathi, S, Paramsivam, M, Singh, T.P. | | 登録日 | 2000-10-22 | | 公開日 | 2003-06-17 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution.
Acta Crystallogr.,Sect.F, 61, 2005
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1G4I
 | | Crystal structure of the bovine pancreatic phospholipase A2 at 0.97A | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... | | 著者 | Steiner, R.A, Rozeboom, H.J, de Vries, A, Kalk, K.H, Murshudov, G.N, Wilson, K.S, Dijkstra, B.W. | | 登録日 | 2000-10-27 | | 公開日 | 2001-04-04 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | X-ray structure of bovine pancreatic phospholipase A2 at atomic resolution.
Acta Crystallogr.,Sect.D, 57, 2001
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1GH4
 | | Structure of the triple mutant (K56M, K120M, K121M) of phospholipase A2 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, PHOSPHOLIPASE A2 | | 著者 | Sekar, K, Velmurugan, D, Tsai, M.D. | | 登録日 | 2000-11-09 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2.
J.Mol.Biol., 324, 2002
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1GMZ
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1GOD
 | | MONOMERIC LYS-49 PHOSPHOLIPASE A2 HOMOLOGUE ISOLATED FROM THE VENOM OF CERROPHIDION (BOTHROPS) GODMANI | | 分子名称: | PROTEIN (PHOSPHOLIPASE A2) | | 著者 | Arni, R.K, Fontes, M.R.M, Barberato, C, Gutierrez, J.M, Diaz-Oreiro, C, Ward, R.J. | | 登録日 | 1999-04-16 | | 公開日 | 1999-04-23 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of myotoxin II, a monomeric Lys49-phospholipase A2 homologue isolated from the venom of Cerrophidion (Bothrops) godmani.
Arch.Biochem.Biophys., 366, 1999
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1GP7
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1HN4
 | | PROPHOSPHOLIPASE A2 DIMER COMPLEXED WITH MJ33, SULFATE, AND CALCIUM | | 分子名称: | 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PROPHOSPHOLIPASE A2, ... | | 著者 | Epstein, T.M, Pan, Y.H, Jain, M.K, Bahnson, B.J. | | 登録日 | 2000-12-06 | | 公開日 | 2001-12-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The basis for k(cat) impairment in prophospholipase A(2) from the anion-assisted dimer structure.
Biochemistry, 40, 2001
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1IJL
 | | Crystal structure of acidic phospholipase A2 from deinagkistrodon acutus | | 分子名称: | CALCIUM ION, PHOSPHOLIPASE A2, ZINC ION | | 著者 | Gu, L, Zhang, H, Song, S, Zhou, Y, Lin, Z. | | 登録日 | 2001-04-27 | | 公開日 | 2001-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of an acidic phospholipase A2 from the venom of Deinagkistrodon acutus.
Acta Crystallogr.,Sect.D, 58, 2002
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1IRB
 | | CARBOXYLIC ESTER HYDROLASE | | 分子名称: | CALCIUM ION, PHOSPHOLIPASE A2 | | 著者 | Sundaralingam, M. | | 登録日 | 1997-08-13 | | 公開日 | 1997-12-24 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interface.
Biochemistry, 35, 1996
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1J1A
 | | PANCREATIC SECRETORY PHOSPHOLIPASE A2 (IIa) WITH ANTI-INFLAMMATORY ACTIVITY | | 分子名称: | (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID, CALCIUM ION, Phospholipase A2 | | 著者 | Hansford, K.A, Reid, R.C, Clark, C.I, Tyndall, J.D.A, Whitehouse, M.W, Guthrie, T, McGeary, R.P, Schafer, K, Martin, J.L, Fairlie, D.P. | | 登録日 | 2002-12-03 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | D-Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (IIa) with Antiinflammatory Activity
Chembiochem, 4, 2003
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1JIA
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1JLT
 | | Vipoxin Complex | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHOLIPASE A2, ... | | 著者 | Banumathi, S, Rajashankar, K.R, Notzel, C, Aleksiev, B, Singh, T.P, Genov, N, Betzel, C. | | 登録日 | 2001-07-16 | | 公開日 | 2001-10-31 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of the neurotoxic complex vipoxin at 1.4 A resolution.
Acta Crystallogr.,Sect.D, 57, 2001
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1JQ8
 | | Design of specific inhibitors of phospholipase A2: Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Leu-Ala-Ile-Tyr-Ser at 2.0 resolution | | 分子名称: | ACETIC ACID, Peptide inhibitor, Phospholipase A2, ... | | 著者 | Chandra, V, Jasti, J, Kaur, P, Dey, S, Betzel, C, Singh, T.P. | | 登録日 | 2001-08-04 | | 公開日 | 2002-11-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS).
ACTA CRYSTALLOGR.,SECT.D, 58, 2002
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1JQ9
 | | Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Phe-Leu-Ser-Tyr-Lys at 1.8 resolution | | 分子名称: | ACETIC ACID, Peptide inhibitor, Phospholipase A2 | | 著者 | Chandra, V, Jasti, J, Kaur, P, Dey, S, Betzel, C, Singh, T.P. | | 登録日 | 2001-08-04 | | 公開日 | 2002-11-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A Resolution
J.BIOL.CHEM., 277, 2002
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1KPM
 | | First Structural Evidence of a Specific Inhibition of Phospholipase A2 by Vitamin E and its Implications in Inflammation: Crystal Structure of the Complex Formed between Phospholipase A2 and Vitamin E at 1.8 A Resolution. | | 分子名称: | ACETIC ACID, Phospholipase A2, VITAMIN E | | 著者 | Chandra, V, Jasti, J, Kaur, P, Betzel, C, Srinivasan, A, Singh, T.P. | | 登録日 | 2002-01-01 | | 公開日 | 2002-07-10 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | First Structural Evidence of a Specific Inhibition of Phospholipase A2 by alpha-Tocopherol (Vitamin E) and its
Implications in Inflammation: Crystal Structure of the Complex Formed Between Phospholipase A2 and
alpha-Tocopherol at 1.8 A Resolution
J.Mol.Biol., 320, 2002
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1KQU
 | | Human phospholipase A2 complexed with a substrate anologue | | 分子名称: | 6-PHENYL-4(R)-(7-PHENYL-HEPTANOYLAMINO)-HEXANOIC ACID, CALCIUM ION, Phospholipase A2, ... | | 著者 | Tyndall, J.D, Martin, J.L. | | 登録日 | 2002-01-07 | | 公開日 | 2003-11-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity.
Chembiochem, 4, 2003
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1KVO
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1KVW
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1KVX
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1KVY
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