PDB: 226 件ウェブページステータス検索Chemie searchBIRD

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2X9H	CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP- METAVANADATE AND PENTACHLOROCARBAZOLE 分子名称: 2,3,4,6,8-PENTACHLORO-9H-CARBAZOL-1-OL, ADP METAVANADATE, MAGNESIUM ION, ... 著者 Selvadurai, J, Kirst, J, Knoelker, H.J, Manstein, D.J. 登録日 2010-03-19 公開日 2011-05-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of Myosin-2 Motor Domain in Complex with Adp-Metavanadate and Pentachlorocarbazole To be Published
2XEL	Molecular Mechanism of Pentachloropseudilin Mediated Inhibition of Myosin Motor Activity 分子名称: 2,4-DICHLORO-6-(3,4,5-TRICHLORO-1H-PYRROL-2YL)PHENOL, ADP METAVANADATE, MAGNESIUM ION, ... 著者 Chinthalapudi, K, Taft, M.H, Martin, R, Hartmann, F.K, Heissler, S.M, Tsiavaliaris, G, Gutzeit, H.O, Knoelker, H.J, Coluccio, L.M, Fedorov, R, Manstein, D.J. 登録日 2010-05-16 公開日 2011-06-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanism and Specificity of Pentachloropseudilin-Mediated Inhibition of Myosin Motor Activity. J.Biol.Chem., 286, 2011
2XO8	Crystal Structure of Myosin-2 in Complex with Tribromodichloropseudilin 分子名称: 2,4-DICHLORO-6-(3,4,5-TRIBROMO-1H-PYRROL-2-YL)PHENOL, ADP METAVANADATE, MAGNESIUM ION, ... 著者 Preller, M, Chinthalapudi, K, Martin, R, Knoelker, H.J, Manstein, D.J. 登録日 2010-08-10 公開日 2011-05-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Inhibition of Myosin ATPase Activity by Halogenated Pseudilins: A Structure-Activity Study. J.Med.Chem., 54, 2011
2Y0R	Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 分子名称: MYOSIN-2 HEAVY CHAIN 著者 Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. 登録日 2010-12-07 公開日 2011-07-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
2Y8I	Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN-2 HEAVY CHAIN 著者 Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. 登録日 2011-02-07 公開日 2011-07-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.132 Å) 主引用文献 Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
2Y9E	Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 分子名称: MYOSIN-2 著者 Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. 登録日 2011-02-14 公開日 2011-07-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.397 Å) 主引用文献 Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
3BZ7	Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II 分子名称: (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Allingham, J.S, Rayment, I. 登録日 2008-01-17 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Org.Biomol.Chem., 6, 2008
3BZ8	Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II 分子名称: (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Allingham, J.S, Rayment, I. 登録日 2008-01-17 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Org.Biomol.Chem., 6, 2008
3BZ9	Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II 分子名称: (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Allingham, J.S, Rayment, I. 登録日 2008-01-17 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Org.Biomol.Chem., 6, 2008
3DTP	Tarantula heavy meromyosin obtained by flexible docking to Tarantula muscle thick filament Cryo-EM 3D-MAP 分子名称: Myosin II regulatory light chain, Myosin light polypeptide 6, Myosin-11,Myosin-7 著者 Alamo, L, Wriggers, W, Pinto, A, Bartoli, F, Salazar, L, Zhao, F.Q, Craig, R, Padron, R. 登録日 2008-07-15 公開日 2008-10-07 最終更新日 2020-01-29 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Three-Dimensional Reconstruction of Tarantula Myosin Filaments Suggests How Phosphorylation May Regulate Myosin Activity J.Mol.Biol., 384, 2008
3I5F	Crystal structure of squid MG.ADP myosin S1 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin catalytic light chain LC-1, ... 著者 Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C. 登録日 2009-07-05 公開日 2009-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure, 15, 2007
3I5G	Crystal structure of rigor-like squid myosin S1 分子名称: CALCIUM ION, MALONATE ION, Myosin catalytic light chain LC-1, ... 著者 Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C. 登録日 2009-07-05 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure, 15, 2007
3I5H	The crystal structure of rigor like squid myosin S1 in the absence of nucleotide 分子名称: CALCIUM ION, Myosin catalytic light chain LC-1, mantle muscle, ... 著者 Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C. 登録日 2009-07-05 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure, 15, 2007
3I5I	The crystal structure of squid myosin S1 in the presence of SO4 2- 分子名称: CALCIUM ION, Myosin catalytic light chain LC-1, mantle muscle, ... 著者 Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C. 登録日 2009-07-05 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure, 15, 2007
3J04	EM structure of the heavy meromyosin subfragment of Chick smooth muscle Myosin with regulatory light chain in phosphorylated state 分子名称: Myosin light polypeptide 6, Myosin regulatory light chain 2, smooth muscle major isoform, ... 著者 Baumann, B.A.J, Taylor, D, Huang, Z, Tama, F, Fagnant, P.M, Trybus, K, Taylor, K. 登録日 2011-02-18 公開日 2011-11-16 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Phosphorylated smooth muscle heavy meromyosin shows an open conformation linked to activation. J.Mol.Biol., 415, 2012
3JAX	Heavy meromyosin from Schistosoma mansoni muscle thick filament by negative stain EM 分子名称: myosin 2 heavy chain, myosin regulatory light chain, smooth muscle myosin essential light chain 著者 Sulbaran, G, Alamo, L, Pinto, A, Marquez, G, Mendez, F, Padron, R, Craig, R. 登録日 2015-07-03 公開日 2015-10-07 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (23 Å) 主引用文献 An invertebrate smooth muscle with striated muscle myosin filaments. Proc.Natl.Acad.Sci.USA, 112, 2015
3JBH	TWO HEAVY MEROMYOSIN INTERACTING-HEADS MOTIFS FLEXIBLE DOCKED INTO TARANTULA THICK FILAMENT 3D-MAP ALLOWS IN DEPTH STUDY OF INTRA- AND INTERMOLECULAR INTERACTIONS 分子名称: MYOSIN 2 ESSENTIAL LIGHT CHAIN STRIATED MUSCLE, MYOSIN 2 HEAVY CHAIN STRIATED MUSCLE, MYOSIN 2 REGULATORY LIGHT CHAIN STRIATED MUSCLE 著者 Alamo, L, Qi, D, Wriggers, W, Pinto, A, Zhu, J, Bilbao, A, Gillilan, R.E, Hu, S, Padron, R. 登録日 2015-09-01 公開日 2016-03-09 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis. J. Mol. Biol., 428, 2016
3L9I	Myosin VI nucleotide-free (mdinsert2) L310G mutant crystal structure 分子名称: ACETATE ION, CALCIUM ION, Calmodulin, ... 著者 Pylypenko, O, Song, L, Sweeney, L.H, Houdusse, A. 登録日 2010-01-05 公開日 2010-12-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Role of insert i of myosin VI in modulating nucleotide affinity To be Published
3MJX	Crystal structure of myosin-2 motor domain in complex with ADP-Metavanadate and blebbistatin 分子名称: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, ADP METAVANADATE, MAGNESIUM ION, ... 著者 Fedorov, R, Baruch, P, Bauer, S, Manstein, D.J. 登録日 2010-04-13 公開日 2011-04-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The mechanism of pentabromopseudilin inhibition of myosin motor activity. Nat.Struct.Mol.Biol., 16, 2009
3MKD	Crystal structure of myosin-2 dictyostelium discoideum motor domain S456Y mutant in complex with adp-orthovanadate 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin-2 heavy chain, ... 著者 Kathmann, D, Diensthuber, R.P, Fedorov, R, Manstein, D.J, Tsiavaliaris, G. 登録日 2010-04-14 公開日 2011-04-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Switch-2 dependent modulation of the myosin power stroke To be Published
3MNQ	Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol 分子名称: 1,2-ETHANEDIOL, ADP METAVANADATE, MAGNESIUM ION, ... 著者 Schneider, J, Taft, M, Backhaus, A, Baruch, P, Fedorov, R, Manstein, D.J. 登録日 2010-04-22 公開日 2011-04-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of resveratrol regulation of myosin activity. To be Published
3MYH	Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 分子名称: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I. 登録日 2010-05-10 公開日 2010-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236 Biochemistry, 49, 2010
3MYK	Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 分子名称: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, MAGNESIUM ION, Myosin-2 heavy chain, ... 著者 Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I. 登録日 2010-05-10 公開日 2010-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236 Biochemistry, 49, 2010
3MYL	Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 分子名称: MAGNESIUM ION, Myosin-2 heavy chain, PYROPHOSPHATE 2- 著者 Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I. 登録日 2010-05-10 公開日 2010-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236 Biochemistry, 49, 2010
4A7F	Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 3) 分子名称: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S. 登録日 2011-11-14 公開日 2012-08-01 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (7.7 Å) 主引用文献 Structure of the Rigor Actin-Tropomyosin-Myosin Complex. Cell(Cambridge,Mass.), 150, 2012

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