PDB: 226 件ウェブページステータス検索Chemie searchBIRD

---

2Y8I	Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN-2 HEAVY CHAIN 著者 Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. 登録日 2011-02-07 公開日 2011-07-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.132 Å) 主引用文献 Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
3JBH	TWO HEAVY MEROMYOSIN INTERACTING-HEADS MOTIFS FLEXIBLE DOCKED INTO TARANTULA THICK FILAMENT 3D-MAP ALLOWS IN DEPTH STUDY OF INTRA- AND INTERMOLECULAR INTERACTIONS 分子名称: MYOSIN 2 ESSENTIAL LIGHT CHAIN STRIATED MUSCLE, MYOSIN 2 HEAVY CHAIN STRIATED MUSCLE, MYOSIN 2 REGULATORY LIGHT CHAIN STRIATED MUSCLE 著者 Alamo, L, Qi, D, Wriggers, W, Pinto, A, Zhu, J, Bilbao, A, Gillilan, R.E, Hu, S, Padron, R. 登録日 2015-09-01 公開日 2016-03-09 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis. J. Mol. Biol., 428, 2016
2Y9E	Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 分子名称: MYOSIN-2 著者 Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. 登録日 2011-02-14 公開日 2011-07-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.397 Å) 主引用文献 Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
3L9I	Myosin VI nucleotide-free (mdinsert2) L310G mutant crystal structure 分子名称: ACETATE ION, CALCIUM ION, Calmodulin, ... 著者 Pylypenko, O, Song, L, Sweeney, L.H, Houdusse, A. 登録日 2010-01-05 公開日 2010-12-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Role of insert i of myosin VI in modulating nucleotide affinity To be Published
3MNQ	Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol 分子名称: 1,2-ETHANEDIOL, ADP METAVANADATE, MAGNESIUM ION, ... 著者 Schneider, J, Taft, M, Backhaus, A, Baruch, P, Fedorov, R, Manstein, D.J. 登録日 2010-04-22 公開日 2011-04-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of resveratrol regulation of myosin activity. To be Published
3MKD	Crystal structure of myosin-2 dictyostelium discoideum motor domain S456Y mutant in complex with adp-orthovanadate 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin-2 heavy chain, ... 著者 Kathmann, D, Diensthuber, R.P, Fedorov, R, Manstein, D.J, Tsiavaliaris, G. 登録日 2010-04-14 公開日 2011-04-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Switch-2 dependent modulation of the myosin power stroke To be Published
3MJX	Crystal structure of myosin-2 motor domain in complex with ADP-Metavanadate and blebbistatin 分子名称: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, ADP METAVANADATE, MAGNESIUM ION, ... 著者 Fedorov, R, Baruch, P, Bauer, S, Manstein, D.J. 登録日 2010-04-13 公開日 2011-04-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The mechanism of pentabromopseudilin inhibition of myosin motor activity. Nat.Struct.Mol.Biol., 16, 2009
1YV3	The structural basis of blebbistatin inhibition and specificity for myosin II 分子名称: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Allingham, J.S, Smith, R, Rayment, I. 登録日 2005-02-14 公開日 2005-03-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structural basis of blebbistatin inhibition and specificity for myosin II. Nat.Struct.Mol.Biol., 12, 2005
3MYH	Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 分子名称: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I. 登録日 2010-05-10 公開日 2010-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236 Biochemistry, 49, 2010
3MYL	Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 分子名称: MAGNESIUM ION, Myosin-2 heavy chain, PYROPHOSPHATE 2- 著者 Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I. 登録日 2010-05-10 公開日 2010-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236 Biochemistry, 49, 2010
3MYK	Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 分子名称: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, MAGNESIUM ION, Myosin-2 heavy chain, ... 著者 Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I. 登録日 2010-05-10 公開日 2010-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236 Biochemistry, 49, 2010
3BZ9	Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II 分子名称: (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Allingham, J.S, Rayment, I. 登録日 2008-01-17 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Org.Biomol.Chem., 6, 2008
3BZ8	Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II 分子名称: (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Allingham, J.S, Rayment, I. 登録日 2008-01-17 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Org.Biomol.Chem., 6, 2008
3BZ7	Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II 分子名称: (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Allingham, J.S, Rayment, I. 登録日 2008-01-17 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Org.Biomol.Chem., 6, 2008
2AKA	Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin 1 from Rattus norvegicus 分子名称: Dynamin-1, LINKER, myosin II heavy chain 著者 Reubold, T.F, Eschenburg, S, Becker, A, Leonard, M, Schmid, S.L, Vallee, R.B, Kull, F.J, Manstein, D.J. 登録日 2005-08-03 公開日 2005-08-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the GTPase domain of rat dynamin 1. Proc.Natl.Acad.Sci.Usa, 102, 2005
2OS8	Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor 分子名称: CALCIUM ION, MAGNESIUM ION, Myosin essential light chain, ... 著者 Yang, Y, Gourinath, S, Cohen, C, Brown, J.H. 登録日 2007-02-05 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.27 Å) 主引用文献 Rigor-like Structures from Muscle Myosins Reveal Key Mechanical Elements in the Transduction Pathways of This Allosteric Motor. Structure, 15, 2007
2OTG	Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... 著者 Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C. 登録日 2007-02-08 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Rigor-like Structures from Muscle Myosins Reveal Key Mechanical Elements in the Transduction Pathways of This Allosteric Motor. Structure, 15, 2007
1B7T	MYOSIN DIGESTED BY PAPAIN 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... 著者 Houdusse, A, Kalabokis, V, Himmel, D, Szent-Gyorgyi, A.G, Cohen, C. 登録日 1999-01-15 公開日 1999-05-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head. Cell(Cambridge,Mass.), 97, 1999
1BR4	SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.BEF3 BOUND AT THE ACTIVE SITE 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Dominguez, R, Trybus, K.M, Cohen, C. 登録日 1998-08-27 公開日 1998-09-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.62 Å) 主引用文献 Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state. Cell(Cambridge,Mass.), 94, 1998
4P7H	Structure of Human beta-Cardiac Myosin Motor Domain::GFP chimera 分子名称: Myosin-7,Green fluorescent protein, SULFATE ION 著者 Winkelmann, D.A, Miller, M.T, Stock, A.M. 登録日 2014-03-27 公開日 2014-05-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of Human beta-Cardiac Myosin Motor Domain at 3.2 A Mol. Biol. Cell, 2011
4PA0	Omecamtiv Mercarbil binding site on the Human Beta-Cardiac Myosin Motor Domain 分子名称: GLYCEROL, Myosin-7,Green fluorescent protein, methyl 4-(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}benzyl)piperazine-1-carboxylate 著者 Winkelmann, D.A, Miller, M.T, Stock, A.M. 登録日 2014-04-06 公開日 2015-07-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis for drug-induced allosteric changes to human beta-cardiac myosin motor activity. Nat Commun, 6, 2015
4PD3	Crystal Structure of Rigor-Like Human Nonmuscle Myosin-2B 分子名称: Nonmuscle myosin heavy chain B, Alpha-actinin A Chimera Protein 著者 Munnich, S, Pathan-Chhatbar, S, Manstein, D.J. 登録日 2014-04-17 公開日 2014-11-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Crystal structure of the rigor-like human non-muscle myosin-2 motor domain. Febs Lett., 588, 2014
4PJK	Dicty myosin II R238E.E459R mutant (with ADP.Pi) in the Pi release state 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. 登録日 2014-05-12 公開日 2015-04-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
1BR2	SMOOTH MUSCLE MYOSIN MOTOR DOMAIN COMPLEXED WITH MGADP.ALF4 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN, ... 著者 Dominguez, R, Trybus, K.M, Cohen, C. 登録日 1998-08-26 公開日 1998-09-09 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state. Cell(Cambridge,Mass.), 94, 1998
1BR1	SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.ALF4 BOUND AT THE ACTIVE SITE 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN, ... 著者 Dominguez, R, Trybus, K.M, Cohen, C. 登録日 1998-08-26 公開日 1998-09-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state. Cell(Cambridge,Mass.), 94, 1998

<12345678910>