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1MY0	crystal titration experiments (AMPA co-crystals soaked in 100 nM BrW) Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
1MXU	CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) in complex with bromo-willardiine (Control for the crystal titration experiments) Descriptor: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
1MXV	crystal titration experiments (AMPA co-crystals soaked in 10 mM BrW) Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
1MY2	crystal titration experiment (AMPA complex control) Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 42, 2003
1MXY	crystal titration experiments (AMPA co-crystals soaked in 10 uM BrW) Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 42, 2003
1MXW	crystal titration experiments (AMPA co-crystals soaked in 1 mM BrW) Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 42, 2003
1MY4	crystal structure of glutamate receptor ligand-binding core in complex with iodo-willardiine in the Zn crystal form Descriptor: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
1MXX	crystal titration experiments (AMPA co-crystals soaked in 100 uM BrW) Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
1MXZ	crystal titration experiments (AMPA co-crystals soaked in 1 uM BrW) Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 42, 2003
1MY1	crystal titration experiments (AMPA co-crystals soaked in 10 nM BrW) Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION Authors: Jin, R, Gouaux, E. Deposit date: 2002-10-03 Release date: 2003-06-10 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
1N0T	X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with the antagonist (S)-ATPO at 2.1 A resolution. Descriptor: (S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID, ACETATE ION, Glutamate receptor 2, ... Authors: Hogner, A, Greenwood, J.R, Liljefors, T, Lunn, M.-L, Egebjerg, J, Larsen, I.K, Gouaux, E, Kastrup, J.S. Deposit date: 2002-10-15 Release date: 2003-03-04 Last modified: 2017-08-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX. J.Med.Chem., 46, 2003
1NNP	X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-ATPA at 1.9 A resolution. Crystallization without zinc ions. Descriptor: 3-(5-TERT-BUTYL-3-OXIDOISOXAZOL-4-YL)-L-ALANINATE, Glutamate receptor 2, SULFATE ION Authors: Lunn, M.L, Hogner, A, Stensbol, T.B, Gouaux, E, Egebjerg, J, Kastrup, J.S. Deposit date: 2003-01-14 Release date: 2003-03-11 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Three-Dimensional Structure of the Ligand-Binding Core of GluR2 in Complex with the Agonist (S)-ATPA: Implications for Receptor Subunit Selectivity. J.Med.Chem., 46, 2003
1NNK	X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-ATPA at 1.85 A resolution. Crystallization with zinc ions. Descriptor: 3-(5-TERT-BUTYL-3-OXIDOISOXAZOL-4-YL)-L-ALANINATE, CHLORIDE ION, Glutamate receptor 2, ... Authors: Lunn, M.-L, Hogner, A, Stensbol, T.B, Gouaux, E, Egebjerg, J, Kastrup, J.S. Deposit date: 2003-01-14 Release date: 2003-03-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Three-Dimensional Structure of the Ligand-Binding Core of GluR2 in Complex with the Agonist (S)-ATPA: Implications for Receptor Subunit Selectivity. J.Med.Chem., 46, 2003
1P1O	Crystal structure of the GluR2 ligand-binding core (S1S2J) mutant L650T in complex with quisqualate Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION Authors: Armstrong, N, Mayer, M.L, Gouaux, E. Deposit date: 2003-04-13 Release date: 2003-06-10 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA, 100, 2003
1P1Q	Crystal structure of the GluR2 ligand binding core (S1S2J) L650T mutant in complex with AMPA Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2, ZINC ION Authors: Armstrong, N, Mayer, M.L, Gouaux, E. Deposit date: 2003-04-13 Release date: 2003-06-10 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA, 100, 2003
1P1N	GluR2 Ligand Binding Core (S1S2J) Mutant L650T in Complex with Kainate Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2 Authors: Armstrong, N, Mayer, M.L, Gouaux, E. Deposit date: 2003-04-13 Release date: 2003-06-10 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA, 100, 2003
1P1W	Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T mutations and in complex with AMPA Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2 precursor, SULFATE ION Authors: Armstrong, N, Mayer, M.L, Gouaux, E. Deposit date: 2003-04-14 Release date: 2003-06-10 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA, 100, 2003
1P1U	Crystal structure of the GluR2 ligand-binding core (S1S2J) L650T mutant in complex with AMPA (ammonium sulfate crystal form) Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2, SULFATE ION Authors: Armstrong, N, Mayer, M.L, Gouaux, E. Deposit date: 2003-04-14 Release date: 2003-06-10 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA, 100, 2003
1PB7	CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH GLYCINE AT 1.35 ANGSTROMS RESOLUTION Descriptor: GLYCINE, N-methyl-D-aspartate Receptor Subunit 1 Authors: Furukawa, H, Gouaux, E. Deposit date: 2003-05-14 Release date: 2003-06-24 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core Embo J., 22, 2003
1PB8	CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-SERINE AT 1.45 ANGSTROMS RESOLUTION Descriptor: D-SERINE, N-methyl-D-aspartate Receptor Subunit 1 Authors: Furukawa, H, Gouaux, E. Deposit date: 2003-05-14 Release date: 2003-06-24 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core Embo J., 22, 2003
1PB9	CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION Descriptor: (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, N-methyl-D-aspartate Receptor Subunit 1 Authors: Furukawa, H, Gouaux, E. Deposit date: 2003-05-14 Release date: 2003-06-24 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core Embo J., 22, 2003
1PBQ	CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION Descriptor: 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, N-methyl-D-aspartate Receptor Subunit 1 Authors: Furukawa, H, Gouaux, E. Deposit date: 2003-05-14 Release date: 2003-07-29 Last modified: 2020-07-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core Embo J., 22, 2003
1S50	X-ray structure of the GluR6 ligand binding core (S1S2A) in complex with glutamate at 1.65 A resolution Descriptor: GLUTAMIC ACID, Glutamate Receptor 6 Authors: Mayer, M.L. Deposit date: 2004-01-19 Release date: 2005-02-08 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005
1S7Y	Crystal structure of the GluR6 ligand binding core in complex with glutamate at 1.75 A resolution orthorhombic form Descriptor: GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 2 precursor Authors: Mayer, M.L. Deposit date: 2004-01-30 Release date: 2005-02-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005
1S9T	Crystal structure of the GLUR6 ligand binding core in complex with quisqualate at 1.8A resolution Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, CHLORIDE ION, Glutamate receptor, ... Authors: Mayer, M.L. Deposit date: 2004-02-05 Release date: 2005-02-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. Neuron, 45, 2005

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