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3NAU
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BU of 3nau by Molmil
Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)
分子名称: SULFATE ION, Zinc fingers and homeoboxes protein 2
著者Ren, J, Bird, L.E, Owens, R.J, Stammers, D.K, Oxford Protein Production Facility (OPPF)
登録日2010-06-02
公開日2010-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains
Bmc Struct.Biol., 10, 2010
7PSX
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BU of 7psx by Molmil
Structure of HOXB13 bound to hydroxymethylated DNA
分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*TP*5HCP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13, ...
著者Morgunova, E, Popov, A, Yin, Y, Taipale, J.
登録日2021-09-24
公開日2022-10-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of HOXB13 bound to hydroxymethylated DNA
To Be Published
7Q3O
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BU of 7q3o by Molmil
Structure of CDX1 bound to hydroxymethylated DNA
分子名称: Homeobox protein CDX-1, hydroxymethylated DNA (18-MER)
著者Morgunova, E, Yin, Y, Popov, A, Taipale, J.
登録日2021-10-28
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Structure of CDX1 bound to hydroxymethylated DNA
To Be Published
4UUT
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BU of 4uut by Molmil
Crystal structure of the Ultrabithorax protein
分子名称: CHLORIDE ION, HOMEOTIC PROTEIN ULTRABITHORAX, SULFATE ION
著者Foos, N, Mate, M.J, Ortiz-Lombardia, M.
登録日2014-07-31
公開日2015-02-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Flexible Extension of the Drosophila Ultrabithorax Homeodomain Defines a Novel Hox/Pbc Interaction Mode.
Structure, 23, 2015
7Q4N
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BU of 7q4n by Molmil
transcription factor CDX2 bound to hydroxymethylated DNA
分子名称: DNA (18-MER), Homeobox protein CDX-2
著者Morgunova, E, Yin, Y, Popov, A, Taipale, J.
登録日2021-11-01
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献transcription factor CDX2 bound to hydroxymethylated DNA
To Be Published
1QRY
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BU of 1qry by Molmil
Homeobox protein VND (ventral nervous system defective protein)
分子名称: PROTEIN (HOMEOBOX VENTRAL NERVOUS SYSTEM DEFECTIVE PROTEIN)
著者Xiang, B.
登録日1999-06-16
公開日1999-07-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Distortion of the three-dimensional structure of the vnd/NK-2 homeodomain bound to DNA induced by an embryonically lethal A35T point mutation.
Biochemistry, 42, 2003
1WI3
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BU of 1wi3 by Molmil
Solution structure of the homeodomain of KIAA1034 protein
分子名称: DNA-binding protein SATB2
著者Izumi, K, Yoshida, M, Hayashi, F, Hatta, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of the homeodomain of KIAA1034 protein
TO BE PUBLISHED
1X2M
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BU of 1x2m by Molmil
Solution structure of the homeobox domain of mouse LAG1 longevity assurance homolog 6
分子名称: LAG1 longevity assurance homolog 6
著者Kamatari, Y.O, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-04-26
公開日2005-10-26
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of the homeobox domain of mouse LAG1 longevity assurance homolog 6
To be Published
4XID
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BU of 4xid by Molmil
AntpHD with 15bp DNA duplex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
著者White, M.A, Zandarashvili, L, Iwahara, J.
登録日2015-01-06
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Biophys.J., 109, 2015
4XIC
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BU of 4xic by Molmil
ANTPHD WITH 15BP di-thioate modified DNA DUPLEX
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C2S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
著者White, M.A, Zandarashvili, L, Iwahara, J.
登録日2015-01-06
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Biophys.J., 109, 2015
1SAN
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BU of 1san by Molmil
THE DES(1-6)ANTENNAPEDIA HOMEODOMAIN: COMPARISON OF THE NMR SOLUTION STRUCTURE AND THE DNA BINDING AFFINITY WITH THE INTACT ANTENNAPEDIA HOMEODOMAIN
分子名称: ANTENNAPEDIA PROTEIN
著者Qian, Y.Q, Resendez-Perez, D, Gehring, W.J, Wuthrich, K.
登録日1994-01-07
公開日1994-04-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The des(1-6)antennapedia homeodomain: comparison of the NMR solution structure and the DNA-binding affinity with the intact Antennapedia homeodomain.
Proc.Natl.Acad.Sci.USA, 91, 1994
1YRN
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BU of 1yrn by Molmil
CRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA
分子名称: DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*TP*AP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*TP*AP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT A1 HOMEODOMAIN), ...
著者Li, T, Stark, M.R, Johnson, A.D, Wolberger, C.
登録日1995-11-02
公開日1996-01-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA.
Science, 270, 1995
8EJO
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BU of 8ejo by Molmil
Crystal structure of the homeodomain of Platypus sDUX in complex with DNA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ...
著者Yin, L.L, Shi, K, Aihara, H.
登録日2022-09-18
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
Iscience, 26, 2023
8EJP
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BU of 8ejp by Molmil
Crystal structure of the homeodomain of Platypus sDUX in complex with DNA containing 5-Bromouracil
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ...
著者Yin, L.L, Shi, K, Aihara, H.
登録日2022-09-18
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.174 Å)
主引用文献Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
Iscience, 26, 2023
8F36
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BU of 8f36 by Molmil
Ubx Homeodomain NMR solution structure
分子名称: Homeotic protein ultrabithorax
著者Beasley, S.A, Loss, J.W, Mekkaoui, F, Advocate, M.R, Spratt, D.E.
登録日2022-11-09
公開日2023-04-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ubx Homeodomain NMR solution structure
To Be Published
8F37
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BU of 8f37 by Molmil
AbdA Homeodomain NMR Solution Structure
分子名称: Homeobox protein abdominal-A
著者Beasley, S.A, Simons, R.A, Advocate, M.R, Mekkaoui, F, Spratt, D.E.
登録日2022-11-09
公開日2023-04-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献AbdA Homeodomain NMR solution structure
To Be Published
8EML
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BU of 8eml by Molmil
Crystal Structure of Gsx2 Homeodomain in Complex with DNA
分子名称: DNA (5'-D(P*GP*AP*GP*CP*TP*AP*AP*TP*TP*AP*AP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*TP*TP*AP*AP*TP*TP*AP*GP*CP*TP*C)-3'), GS homeobox 2, ...
著者Webb, J.A, Kovall, R.A.
登録日2022-09-28
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal Structure of Gsx2 Homeodomain in Complex with DNA
To Be Published
1ZQ3
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BU of 1zq3 by Molmil
NMR Solution Structure of the Bicoid Homeodomain Bound to the Consensus DNA Binding Site TAATCC
分子名称: 5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3', 5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3', Homeotic bicoid protein
著者Baird-Titus, J.M, Rance, M, Clark-Baldwin, K, Ma, J, Vrushank, D.
登録日2005-05-18
公開日2006-02-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site.
J.Mol.Biol., 356, 2006
1ZTR
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BU of 1ztr by Molmil
Solution structure of Engrailed homeodomain L16A mutant
分子名称: Segmentation polarity homeobox protein engrailed
著者Religa, T.L, Markson, J.S, Mayor, U, Freund, S.M.V, Fersht, A.R.
登録日2005-05-27
公開日2005-10-18
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Solution structure of a protein denatured state and folding intermediate.
Nature, 437, 2005
5EF6
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BU of 5ef6 by Molmil
Structure of HOXB13 complex with methylated DNA
分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-23
公開日2017-02-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science, 356, 2017
1UHS
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BU of 1uhs by Molmil
Solution structure of mouse homeodomain-only protein HOP
分子名称: homeodomain only protein
著者Saito, K, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-07-10
公開日2004-07-10
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of mouse homeodomain-only protein HOP
To be Published
5EEA
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BU of 5eea by Molmil
Structure of HOXB13-DNA(CAA) complex
分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*CP*AP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*TP*TP*GP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-22
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Elife, 7, 2018
5EDN
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BU of 5edn by Molmil
Structure of HOXB13-DNA(TCG) complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(P*GP*GP*AP*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*GP*TP*CP*C)-3'), ...
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-21
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Elife, 7, 2018
1VND
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BU of 1vnd by Molmil
VND/NK-2 PROTEIN (HOMEODOMAIN), NMR
分子名称: VND/NK-2 PROTEIN
著者Tsao, D.H.H, Gruschus, J.M, Wang, L.-H, Nirenberg, M, Ferretti, J.A.
登録日1996-05-22
公開日1996-11-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The three-dimensional solution structure of the NK-2 homeodomain from Drosophila.
J.Mol.Biol., 251, 1995
6RYD
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BU of 6ryd by Molmil
WUS-HD bound to TGAA DNA
分子名称: DNA (5'-D(*AP*GP*TP*GP*TP*AP*TP*GP*AP*AP*TP*GP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*CP*AP*TP*TP*CP*AP*TP*AP*CP*AP*CP*T)-3'), MAGNESIUM ION, ...
著者Sloan, J.J, Wild, K, Sinning, I.
登録日2019-06-10
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.575 Å)
主引用文献Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020

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