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7STZ
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BU of 7stz by Molmil
Crystal Structure of Human E-cadherin EC1-5 bound by mouse monoclonal antibody Fab mAb-1_19A11
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-11-15
Release date:2022-01-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography.
Pnas Nexus, 1, 2022
2WBX
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BU of 2wbx by Molmil
Crystal structure of mouse cadherin-23 EC1
Descriptor: CADHERIN-23, CALCIUM ION
Authors:Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P.
Deposit date:2009-03-05
Release date:2010-04-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Determinants of Cadherin-23 Function in Hearing and Deafness.
Neuron, 66, 2010
8HYI
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BU of 8hyi by Molmil
Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine
Descriptor: 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ...
Authors:Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K.
Deposit date:2023-01-06
Release date:2023-08-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Modulation of a conformational ensemble by a small molecule that inhibits key protein-protein interactions involved in cell adhesion.
Protein Sci., 32, 2023
8TRI
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BU of 8tri by Molmil
Crystal Structure of Mouse Cadherin-23 EC25-MAD28 F2894A
Descriptor: CALCIUM ION, Cadherin-23
Authors:Ashraf, Q, Sotomayor, M.
Deposit date:2023-08-09
Release date:2024-08-28
Method:X-RAY DIFFRACTION (3.716 Å)
Cite:Crystal Structure of Mouse Cadherin-23 EC25-MAD28 F2894A
To be published
2EE0
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BU of 2ee0 by Molmil
Solution structures of the CA domain of human protocadherin 9
Descriptor: Protocadherin-9
Authors:Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-15
Release date:2007-08-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structures of the CA domain of human protocadherin 9
To be Published
2O72
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BU of 2o72 by Molmil
Crystal Structure Analysis of human E-cadherin (1-213)
Descriptor: CALCIUM ION, Epithelial-cadherin
Authors:Parisini, E, Wang, J.-H.
Deposit date:2006-12-09
Release date:2007-10-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism
J.Mol.Biol., 373, 2007
6CGB
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BU of 6cgb by Molmil
chimera of mouse cadherin-11 EC1 and mouse cadherin-6 EC2
Descriptor: ACETATE ION, CALCIUM ION, Cadherin-11, ...
Authors:Brasch, J, Harrison, O.J, Shapiro, L, Kaeser, B.
Deposit date:2018-02-19
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.994 Å)
Cite:Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior.
Cell Rep, 23, 2018
6CXY
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BU of 6cxy by Molmil
Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody Fab mAb-1_19A11
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Cadherin-1, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-04-04
Release date:2019-04-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody Fab mAb-1_19A11
to be published
7N86
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BU of 7n86 by Molmil
Crystal Structure of Human Protocadherin-24 EC1-2 Form II
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Modak, D, Gray, M.E, Sotomayor, M.
Deposit date:2021-06-13
Release date:2021-09-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.175 Å)
Cite:Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.
Plos Biol., 19, 2021
7N4P
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BU of 7n4p by Molmil
Crystal Structure of Lizard Cadherin-23 EC1-2
Descriptor: CALCIUM ION, Cadherin 23, SODIUM ION
Authors:Nisler, C.R, Sotomayor, M.
Deposit date:2021-06-04
Release date:2022-06-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation.
Mol.Biol.Evol., 40, 2023
1Q1P
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BU of 1q1p by Molmil
E-Cadherin activation
Descriptor: CALCIUM ION, Epithelial-cadherin
Authors:Haussinger, D, Stetefeld, J.
Deposit date:2003-07-22
Release date:2004-04-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography.
Embo J., 23, 2004
5WJ8
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BU of 5wj8 by Molmil
Crystal Structure of Human Cadherin-23 EC13-14
Descriptor: CALCIUM ION, CHLORIDE ION, Cadherin-23, ...
Authors:Velez-Cortes, F, Conghui, C, De-la-Torre, P, Sotomayor, M.
Deposit date:2017-07-21
Release date:2018-07-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Structure, 26, 2018
5WJM
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BU of 5wjm by Molmil
Crystal Structure of Mouse Cadherin-23 EC17-18
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Cadherin-23, ...
Authors:De-la-Torre, P, Sotomayor, M.
Deposit date:2017-07-23
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Structure, 26, 2018
7SKH
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BU of 7skh by Molmil
Crystal Structure of Mouse Cadherin-23 EC16-17
Descriptor: CALCIUM ION, Cadherin-23
Authors:Sudar, J.C, Sandhu, J.S, Sotomayor, M.
Deposit date:2021-10-20
Release date:2022-10-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.265 Å)
Cite:Crystal Structure of Mouse Cadherin-23 EC16-17
to be published
1EDH
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BU of 1edh by Molmil
E-CADHERIN DOMAINS 1 AND 2 IN COMPLEX WITH CALCIUM
Descriptor: CALCIUM ION, E-CADHERIN, MERCURY (II) ION
Authors:Nagar, B, Overduin, M, Ikura, M, Rini, J.M.
Deposit date:1996-05-15
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of calcium-induced E-cadherin rigidification and dimerization.
Nature, 380, 1996
1SUH
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BU of 1suh by Molmil
AMINO-TERMINAL DOMAIN OF EPITHELIAL CADHERIN IN THE CALCIUM BOUND STATE, NMR, 20 STRUCTURES
Descriptor: EPITHELIAL CADHERIN
Authors:Overduin, M, Tong, K.I, Kay, C.M, Ikura, M.
Deposit date:1996-01-30
Release date:1996-07-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:1H, 15N and 13C resonance assignments and monomeric structure of the amino-terminal extracellular domain of epithelial cadherin.
J.Biomol.NMR, 7, 1996
1FF5
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BU of 1ff5 by Molmil
STRUCTURE OF E-CADHERIN DOUBLE DOMAIN
Descriptor: CALCIUM ION, EPITHELIAL CADHERIN
Authors:Pertz, O, Bozic, D, Koch, A.W, Fauser, C, Brancaccio, A, Engel, J.
Deposit date:2000-07-25
Release date:2000-08-23
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation.
EMBO J., 18, 1999
5ERP
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BU of 5erp by Molmil
Crystal structure of human Desmocollin-2 ectodomain fragment EC2-5
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2015-11-14
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of adhesive binding by desmocollins and desmogleins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5ERD
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BU of 5erd by Molmil
Crystal structure of human Desmoglein-2 ectodomain
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Brasch, J, Harrison, O.J, Shapiro, L.
Deposit date:2015-11-13
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of adhesive binding by desmocollins and desmogleins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EQX
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BU of 5eqx by Molmil
Crystal structure of human Desmoglein-3 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2015-11-13
Release date:2016-06-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis of adhesive binding by desmocollins and desmogleins.
Proc.Natl.Acad.Sci.USA, 113, 2016
3UBH
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BU of 3ubh by Molmil
Crystal structure of Drosophila N-cadherin EC1-4
Descriptor: CALCIUM ION, Neural-cadherin
Authors:Jin, X, Walker, M.A, Shapiro, L.
Deposit date:2011-10-24
Release date:2011-12-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UBF
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BU of 3ubf by Molmil
Crystal structure of Drosophila N-cadherin EC1-3, I
Descriptor: CALCIUM ION, Neural-cadherin, ZINC ION
Authors:Jin, X, Walker, M.A, Shapiro, L.
Deposit date:2011-10-24
Release date:2011-12-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UBG
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BU of 3ubg by Molmil
Crystal structure of Drosophila N-cadherin EC1-3, II
Descriptor: CALCIUM ION, Neural-cadherin, ZINC ION
Authors:Jin, X, Walker, M.A, Shapiro, L.
Deposit date:2011-10-24
Release date:2011-12-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers.
Proc.Natl.Acad.Sci.USA, 109, 2012
5VVM
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BU of 5vvm by Molmil
Crystal structure of human CDH23 EC21-23
Descriptor: CALCIUM ION, Cadherin-23
Authors:Patel, A, Jaiganesh, A, Sotomayor, M.
Deposit date:2017-05-19
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Structure, 26, 2018
5W1D
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BU of 5w1d by Molmil
Crystal Structure of Mouse Protocadherin-15 EC4-7
Descriptor: CALCIUM ION, POTASSIUM ION, Protocadherin-15
Authors:Klanseck, C.F, Neel, B.L, Sotomayor, M.
Deposit date:2017-06-02
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Proc.Natl.Acad.Sci.USA, 2020

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