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8IO5	Herg1a-herg1b closed state 2 Descriptor: Potassium voltage-gated channel subfamily H member 2 Authors: Zhang, M.F. Deposit date: 2023-03-10 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of Herg1a-herg1b open state To Be Published
8IOB	Herg1a-herg1b closed state 1 Descriptor: Potassium voltage-gated channel subfamily H member 2 Authors: Zhang, M.F. Deposit date: 2023-03-10 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structure of Herg1a-herg1b closed state 1 To Be Published
8EOW	Eag Kv channel with voltage sensor in the up conformation Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 Authors: Mandala, V.S, MacKinnon, R. Deposit date: 2022-10-04 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
8EP1	Eag Kv channel with voltage sensor in the down conformation Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 Authors: Mandala, V.S, MacKinnon, R. Deposit date: 2022-10-04 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (5.4 Å) Cite: Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
8EP0	Eag Kv channel with voltage sensor in the intermediate conformation Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 Authors: Mandala, V.S, MacKinnon, R. Deposit date: 2022-10-04 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
8J2M	The truncated rice Na+/H+ antiporter SOS1 (1-976) in a constitutively active state Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, Na+/H+ antiporter Authors: Zhang, X.Y, Tang, L.H, Zhang, C.R, Nie, J.W. Deposit date: 2023-04-14 Release date: 2023-11-22 Last modified: 2023-11-29 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure and activation mechanism of the rice Salt Overly Sensitive 1 (SOS1) Na + /H + antiporter. Nat.Plants, 9, 2023
8IWO	The rice Na+/H+ antiporter SOS1 in an auto-inhibited state Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, OsSOS1 Authors: Zhang, X.Y, Tang, L.H, Zhang, C.R, Nie, J.W. Deposit date: 2023-03-30 Release date: 2023-11-22 Last modified: 2023-11-29 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: Structure and activation mechanism of the rice Salt Overly Sensitive 1 (SOS1) Na + /H + antiporter. Nat.Plants, 9, 2023
8EU3	Cryo-EM structure of cGMP bound human CNGA3/CNGB3 channel in GDN, transition state 1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... Authors: Hu, Z, Zheng, X, Yang, J. Deposit date: 2022-10-18 Release date: 2023-08-02 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
8ETP	Cryo-EM structure of cGMP bound closed state of human CNGA3/CNGB3 channel in GDN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... Authors: Hu, Z, Zheng, X, Yang, J. Deposit date: 2022-10-17 Release date: 2023-08-02 Method: ELECTRON MICROSCOPY (3.52 Å) Cite: Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
8EV8	Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, closed state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... Authors: Hu, Z, Yang, J. Deposit date: 2022-10-20 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (3.11 Å) Cite: Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
8EVC	Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, open state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... Authors: Hu, Z, Yang, J. Deposit date: 2022-10-20 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (3.33 Å) Cite: Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
8EVB	Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, pre-open state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... Authors: Hu, Z, Yang, J. Deposit date: 2022-10-20 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
8EVA	Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, transition state 2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... Authors: Hu, Z, Yang, J. Deposit date: 2022-10-20 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (3.33 Å) Cite: Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
8EV9	Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, transition state 1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... Authors: Hu, Z, Yang, J. Deposit date: 2022-10-20 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (3.33 Å) Cite: Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
8EUC	Cryo-EM structure of cGMP bound human CNGA3/CNGB3 channel in GDN, transition state 2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... Authors: Hu, Z, Zheng, X, Yang, J. Deposit date: 2022-10-18 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (3.61 Å) Cite: Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
8IO4	Herg1a-herg1b open state Descriptor: Potassium voltage-gated channel subfamily H member 2 Authors: Zhang, M.F. Deposit date: 2023-03-10 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structure of Herg1a-herg1b open state To Be Published
8INZ	Cryo-EM structure of human HCN3 channel in apo state Descriptor: 4-[[(2~{S},4~{a}~{R},6~{S},8~{a}~{S})-6-[(4~{S},5~{R})-4-[(2~{S})-butan-2-yl]-5,9-dimethyl-decyl]-4~{a}-methyl-2,3,4,5,6,7,8,8~{a}-octahydro-1~{H}-naphthalen-2-yl]oxy]-4-oxidanylidene-butanoic acid, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 Authors: Yu, B, Lu, Q.Y, Li, J, Zhang, J. Deposit date: 2023-03-10 Release date: 2024-04-10 Method: ELECTRON MICROSCOPY (2.72 Å) Cite: Cryo-EM structure of human HCN3 channel in apo state To Be Published
5CIZ	E. coli RNA polymerase alpha subunit CTD in complex with CAP and DNA: A(5)-tract binding site for alpha CTD Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*CP*AP*AP*AP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*TP*TP*TP*GP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3'), ... Authors: Napoli, A.A, Lawson, C.L. Deposit date: 2015-07-13 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (5.0098 Å) Cite: The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element Biochemistry, 2020
4EV0	Crystal Structure of Thermus thermophilus Catabolite Activator Protein Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... Authors: Hudson, B.P, Turo, K, Birktoft, J.J, Lawson, C.L. Deposit date: 2012-04-25 Release date: 2012-06-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.402 Å) Cite: Crystal Structure of T. thermophilius Catabolite Activator Protein To be Published
4F7Z	Conformational dynamics of exchange protein directly activated by cAMP Descriptor: GLYCEROL, Rap guanine nucleotide exchange factor 4 Authors: White, M.A, Tsalkova, T.N, Mei, F.C, Liu, T, Woods, V.L, Cheng, X. Deposit date: 2012-05-16 Release date: 2012-10-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP. Plos One, 7, 2012
5CVR	Crystal structure of FNR of A. fischeri in a partially degraded form Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, FE2/S2 (INORGANIC) CLUSTER, FNR type regulator Authors: Volbeda, A, Fontecilla-Camps, J.C. Deposit date: 2015-07-27 Release date: 2015-12-16 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium. Sci Adv, 1, 2015
4FT8	E. coli Catabolite Activator Protein with Cobalt and Sulfate Ligands Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, COBALT (II) ION, Catabolite gene activator, ... Authors: Rao, R, Lawson, C.L. Deposit date: 2012-06-27 Release date: 2013-12-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.966 Å) Cite: Structure of catabolite activator protein with cobalt(II) and sulfate. Acta Crystallogr F Struct Biol Commun, 70, 2014
5DYL	Crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium Vivax - Apo form Descriptor: cGMP-dependent protein kinase, putative Authors: Wernimont, A.K, Tempel, W, He, H, Seitova, A, Hills, T, Neculai, A.M, Baker, D.A, Flueck, C, Kettleborough, C.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Hutchinson, A, El Bakkouri, M, Structural Genomics Consortium (SGC) Deposit date: 2015-09-24 Release date: 2015-11-04 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation. Proc.Natl.Acad.Sci.USA, 116, 2019
5E44	Crystal structure of holo-FNR of A. fischeri Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, FNR regulator, IRON/SULFUR CLUSTER Authors: Volbeda, A, Fontecilla-Camps, J.C. Deposit date: 2015-10-05 Release date: 2015-12-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.65 Å) Cite: The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium. Sci Adv, 1, 2015
5DYK	Crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium falciparum - Apo form Descriptor: 1,2-ETHANEDIOL, CGMP-dependent protein kinase, GLYCEROL, ... Authors: Wernimont, A.K, Tempel, W, He, H, Seitova, A, Hills, T, Neculai, A.M, Baker, D.A, Flueck, C, Kettleborough, C.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Hutchinson, A, El Bakkouri, M, Structural Genomics Consortium (SGC) Deposit date: 2015-09-24 Release date: 2015-11-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation. Proc.Natl.Acad.Sci.USA, 116, 2019

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