PDB: 522 resultsInfo pagesStatus searchChemie searchBIRD

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5NP5	Abl2 SH3 pTyr116/161 Descriptor: Abelson tyrosine-protein kinase 2, SULFATE ION Authors: Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. Deposit date: 2017-04-13 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
3EG3	Crystal structure of the N114A mutant of ABL-SH3 domain Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2008-09-10 Release date: 2009-09-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285, 2010
4J9E	Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17 Descriptor: P17, SULFATE ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17 To be Published
5FWC	Human Spectrin SH3 domain D48G, E7A, K60A Descriptor: 1,2-ETHANEDIOL, AMMONIUM ION, SPECTRIN ALPHA CHAIN, ... Authors: Gallego, P, Navarro, S, Ventura, S, Reverter, D. Deposit date: 2016-02-12 Release date: 2016-12-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Human Spectrin SH3 Domain D48G, E7A, K60A To be Published
2DRK	Acanthamoeba myosin I SH3 domain bound to Acan125 Descriptor: 10-mer peptide from Myosin-I binding protein Acan125, GLYCEROL, Myosin heavy chain IB, ... Authors: Houdusse, A, Bahloul, A, Ostap, E.M. Deposit date: 2006-06-09 Release date: 2007-05-29 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.42 Å) Cite: The crystal structure of the SH3 domain of Acanthamoeba myosin IB bound to Acan125 To be Published
7PVX	Crystal structure of the c-Src SH3 domain mutant E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H in complex with the synthetic peptide VSL12 Descriptor: Isoform 1 of Proto-oncogene tyrosine-protein kinase Src, VSL12 peptide Authors: Camara-Artigas, A, Salinas Garcia, M.C. Deposit date: 2021-10-05 Release date: 2022-09-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystal structure of the c-Src SH3 domain mutants of the specificity region in complex with polyproline peptides To be published
7TZK	EPS8 SH3 Domain with NleH1 PxxDY Motif Descriptor: Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog Authors: Grishin, A.M, Cygler, M. Deposit date: 2022-02-15 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli Proc.Natl.Acad.Sci.USA, 119, 2022
5UL6	The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions Descriptor: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus Authors: Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. Deposit date: 2017-01-24 Release date: 2017-08-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus. ACS Chem. Biol., 12, 2017
5IHI	Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, Spectrin alpha chain, ... Authors: Camara-Artigas, A. Deposit date: 2016-02-29 Release date: 2017-03-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G to be published
3I9Q	Crystal Structure of the triple mutant S19G-P20D-R21S of alpha spectrin SH3 domain Descriptor: SULFATE ION, Spectrin alpha chain Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2009-07-12 Release date: 2009-12-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The effect of a proline residue on the rate of growth and the space group of alpha-spectrin SH3-domain crystals. Acta Crystallogr.,Sect.D, 65, 2009
1W70	SH3 domain of p40phox complexed with C-terminal polyProline region of p47phox Descriptor: NEUTROPHIL CYTOSOL FACTOR 1, NEUTROPHIL CYTOSOL FACTOR 4, SULFATE ION, ... Authors: Massenet, C, Chenavas, S, Cohen-Addad, C, Dagher, M.-C, Brandolin, G, Pebay-Peyroula, E, Fieschi, F. Deposit date: 2004-08-26 Release date: 2005-01-18 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.46 Å) Cite: Effects of P47Phox C-Terminus Phosphorylation on Binding Interactions with P40Phox and P67Phox: Structural and Functional Comparison of P40Phox P67Phox SH3 Domains J.Biol.Chem., 280, 2005
1U06	crystal structure of chicken alpha-spectrin SH3 domain Descriptor: AZIDE ION, Spectrin alpha chain, brain Authors: Chevelkov, V, Faelber, K, Diehl, A, Heinemann, U, Oschkinat, H, Reif, B. Deposit date: 2004-07-13 Release date: 2005-01-13 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR. J.Biomol.Nmr, 31, 2005
1CKA	STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, C3G PEPTIDE (PRO-PRO-PRO-ALA-LEU-PRO-PRO-LYS-LYS-ARG) Authors: Wu, X, Kuriyan, J. Deposit date: 1995-01-24 Release date: 1995-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure, 3, 1995
7PVW	Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H mutant Descriptor: ACETATE ION, Isoform 1 of Proto-oncogene tyrosine-protein kinase Src, TETRAETHYLENE GLYCOL Authors: Camara-Artigas, A, Salinas Garcia, M.C. Deposit date: 2021-10-05 Release date: 2022-09-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7NET	Crystal structure of the v-Src SH3 domain W95R-I96T mutant Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, TRIETHYLENE GLYCOL, ... Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
5IHN	Crystal Structure of the alpha spectrin SH3 domain mutant N47G Descriptor: FORMIC ACID, SODIUM ION, Spectrin alpha chain, ... Authors: Camara-Artigas, A. Deposit date: 2016-02-29 Release date: 2017-03-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain mutant N47G to be published
2O31	Crystal structure of the second SH3 domain from ponsin Descriptor: FORMIC ACID, Ponsin Authors: Pinotsis, N, Wilmanns, M, Margiolaki, I. Deposit date: 2006-11-30 Release date: 2007-10-23 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Second SH3 domain of ponsin solved from powder diffraction J.Am.Chem.Soc., 129, 2007
2XMF	Myosin 1e SH3 Descriptor: MYOSIN 1E SH3, OCTANE 1,8-DIAMINE Authors: Edwards, T, Allsop, G, Peckham, M. Deposit date: 2010-07-27 Release date: 2011-08-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Myosin 1E SH3 To be Published
1UTI	Mona/Gads SH3C in complex with HPK derived peptide Descriptor: GRB2-RELATED ADAPTOR PROTEIN 2, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1 Authors: Lewitzky, M, Harkiolaki, M, Domart, M.C, Feller, S.M. Deposit date: 2003-12-09 Release date: 2004-05-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Mona/Gads Sh3C Binding to Hematopoietic Progenitor Kinase 1 (Hpk1) Combines an Atypical SH3 Binding Motif, R/Kxxk, with a Classical Pxxp Motif Embedded in a Polyproline Type II (Ppii) Helix J.Biol.Chem., 279, 2004
3UA7	Crystal Structure of the Human Fyn SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein Descriptor: CHLORIDE ION, FORMIC ACID, GLYCEROL, ... Authors: Martin-Garcia, J.M, Ruiz-Sanz, J, Luque, I, Camara-Artigas, A. Deposit date: 2011-10-21 Release date: 2012-07-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein. Acta Crystallogr.,Sect.D, 68, 2012
1FMK	CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC Descriptor: TYROSINE-PROTEIN KINASE SRC Authors: Xu, W, Harrison, S.C, Eck, M.J. Deposit date: 1997-01-24 Release date: 1997-08-20 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Three-dimensional structure of the tyrosine kinase c-Src. Nature, 385, 1997
7A2J	Crystal structure of the Fyn SH3 domain in space group C21 at pH 7.5 Descriptor: SODIUM ION, Tyrosine-protein kinase Fyn Authors: Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C. Deposit date: 2020-08-18 Release date: 2021-08-25 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of the Fyn SH3 domain in space group C21 at pH 7.5 To be published
7A2M	Crystal structure of the Fyn SH3 domain A95S-D99T mutant in C21 space group Descriptor: FORMIC ACID, SODIUM ION, SULFATE ION, ... Authors: Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C. Deposit date: 2020-08-18 Release date: 2021-08-25 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of the Fyn SH3 domain A95S-D99T mutant in C21 space group To be published
7A2K	Crystal structure of the Fyn SH3 domain in space group P1 at pH 7.5 Descriptor: SODIUM ION, Tyrosine-protein kinase Fyn Authors: Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C. Deposit date: 2020-08-18 Release date: 2021-08-25 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of the Fyn SH3 domain in space group P1 at pH 7.5 To be published
7A36	Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 7 M urea Descriptor: Proto-oncogene tyrosine-protein kinase Src, SODIUM ION, UREA Authors: Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C. Deposit date: 2020-08-18 Release date: 2021-08-25 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 7 M urea To be published

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