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7S4R
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Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - alpha Spectrin-SH3 domain
分子名称: Spectrin alpha chain, non-erythrocytic 1
著者Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X.
登録日2021-09-09
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Serial macromolecular crystallography at ALBA Synchrotron Light Source.
J.Synchrotron Radiat., 29, 2022
7TPB
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p120RasGAP SH3 domain in complex with DLC1 RhoGAP domain
分子名称: Ras GTPase-activating protein 1, Rho GTPase-activating protein 7
著者Stiegler, A.L, Boggon, T.J, Chau, J.E, Vish, K.J.
登録日2022-01-25
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP.
Nat Commun, 13, 2022
7TZK
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EPS8 SH3 Domain with NleH1 PxxDY Motif
分子名称: Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog
著者Grishin, A.M, Cygler, M.
登録日2022-02-15
公開日2022-07-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli
Proc.Natl.Acad.Sci.USA, 119, 2022
7Y4N
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Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos
分子名称: Growth factor receptor-bound protein 2
著者Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y.
登録日2022-06-15
公開日2022-08-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos.
Biochem.Biophys.Res.Commun., 625, 2022
7YXW
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Structure of the p22phox A200G mutant in complex with p47phox peptide
分子名称: Cytochrome b-245 light chain, Neutrophil cytosol factor 1
著者Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z.
登録日2022-02-16
公開日2022-03-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics
Acs Med.Chem.Lett., 13, 2022
6XVN
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Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 1
分子名称: Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Plaza-Garrido, M.
登録日2020-01-22
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XVM
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Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 2
分子名称: GLYCEROL, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Plaza-Garrido, M.
登録日2020-01-22
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XVO
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Crystal structure of the intertwined dimer of the c-Src SH3 domain without ATCUN motif
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
著者Camara-Artigas, A, Plaza-Garrido, M.
登録日2020-01-22
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX4
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Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
分子名称: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2020-01-26
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX3
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Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Cu(II) at pH 6.5 co-crystallized with methyl beta-cyclodextrin
分子名称: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2020-01-26
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX5
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Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
分子名称: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2020-01-26
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX2
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Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Cu(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
分子名称: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2020-01-26
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
2XMF
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Myosin 1e SH3
分子名称: MYOSIN 1E SH3, OCTANE 1,8-DIAMINE
著者Edwards, T, Allsop, G, Peckham, M.
登録日2010-07-27
公開日2011-08-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Myosin 1E SH3
To be Published
2YUP
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Solution structure of the second SH3 domain of human Vinexin
分子名称: Vinexin
著者Abe, H, Tochio, N, Miyamoto, K, Saito, K, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-06
公開日2007-10-09
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the second SH3 domain of human Vinexin
To be Published
2YT6
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Solution structure of the SH3_1 domain of Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
分子名称: Adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530076O17 product:Yamaguchi sarcoma viral (v-yes) oncogene homolog
著者Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2008-04-08
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3_1 domain of Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
To be Published
2YUO
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Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3
分子名称: RUN and TBC1 domain containing 3
著者Abe, H, Tochio, N, Miyamoto, K, Saito, K, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-06
公開日2007-10-09
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3
To be Published
2YUQ
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Solution structure of the SH3 domain of human Tyrosine-protein kinase ITK/TSK
分子名称: Tyrosine-protein kinase ITK/TSK
著者Abe, H, Miyamoto, K, Tochio, N, Sato, M, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-06
公開日2007-10-09
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3 domain of human Tyrosine-protein kinase ITK/TSK
To be Published
3C0C
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BU of 3c0c by Molmil
X-ray Crystal Structure of the Rat Endophilin A2 SH3 Domain
分子名称: Endophilin-A2
著者Loll, P.J, Swain, E.
登録日2008-01-19
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the SH3 domain of rat endophilin A2
To be Published
3CQT
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N53I V55L MUTANT of FYN SH3 DOMAIN
分子名称: Proto-oncogene tyrosine-protein kinase Fyn
著者Neculai, A.M, Zarrine-Afsar, A, Howell, P.L, Davidson, A, Chan, H.S.
登録日2008-04-03
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4EIK
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Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12
分子名称: SODIUM ION, Tyrosine-protein kinase Fyn, VSL12 peptide
著者Camara-Artigas, A.
登録日2012-04-05
公開日2013-04-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex.
Acta Crystallogr F Struct Biol Commun, 72, 2016
4ESR
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Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors
分子名称: DI(HYDROXYETHYL)ETHER, Jouberin
著者Van Petegem, X.F, Liu, P.X, Lobo, P, Jiang, X.
登録日2012-04-23
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors.
Proteomics, 12, 2012
4F16
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Crystal Structure of the alpha spectrin SH3 domain at pH 5
分子名称: Spectrin alpha chain, brain
著者Camara-Artigas, A, Gavira, J.A.
登録日2012-05-06
公開日2013-05-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal Structure of the alpha spectrin SH3 domain at pH 5
To be Published
4F17
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Crystal Structure of the alpha spectrin SH3 domain at pH 9
分子名称: Spectrin alpha chain, brain
著者Camara-Artigas, A, Gavira, J.A.
登録日2012-05-06
公開日2013-05-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal Structure of the alpha spectrin SH3 domain at pH 9
To be Published
4FSS
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Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution
分子名称: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
著者Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
登録日2012-06-27
公開日2012-07-18
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution
To be published
3SEM
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SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR
分子名称: SEX MUSCLE ABNORMAL PROTEIN 5, SH3 PEPTOID INHIBITOR
著者Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A.
登録日1998-11-02
公開日1999-01-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998

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