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7Y4N
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Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos
分子名称: Growth factor receptor-bound protein 2
著者Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y.
登録日2022-06-15
公開日2022-08-31
実験手法SOLUTION NMR
主引用文献Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos.
Biochem.Biophys.Res.Commun., 625, 2022
5L23
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BU of 5l23 by Molmil
Crystal structure of the complex between the N-terminal SH3 domain of CrkII and a proline-rich ligand
分子名称: Adapter molecule crk, C3G derived peptide, DI(HYDROXYETHYL)ETHER
著者Bhatt, V.S, Krieger, I, Sacchettini, J, Cho, J.-H.
登録日2016-07-30
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal structure of the complex between the N-terminal SH3 domain of CrkII and a proline-rich ligand
To Be Published
7NET
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BU of 7net by Molmil
Crystal structure of the v-Src SH3 domain W95R-I96T mutant
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021
7NES
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BU of 7nes by Molmil
Crystal structure of the v-Src SH3 domain N117D-V124L mutant
分子名称: GLYCINE, v-Src SH3 domain
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2021-06-16
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021
7NER
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Crystal structure of the v-Src SH3 domain Q128R mutant
分子名称: SULFATE ION, TETRAETHYLENE GLYCOL, v-Src SH3 domain
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021
7YXW
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BU of 7yxw by Molmil
Structure of the p22phox A200G mutant in complex with p47phox peptide
分子名称: Cytochrome b-245 light chain, Neutrophil cytosol factor 1
著者Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z.
登録日2022-02-16
公開日2022-03-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics
Acs Med.Chem.Lett., 13, 2022
7NZC
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BU of 7nzc by Molmil
First SH3 domain of POSH (Plenty of SH3 Domains protein)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase SH3RF1
著者Palencia, A, Bessa, L.M, Jensen, M.R.
登録日2021-03-23
公開日2021-12-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.111 Å)
主引用文献Visualizing protein breathing motions associated with aromatic ring flipping.
Nature, 602, 2022
5NP3
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Abl2 SH3
分子名称: Abelson tyrosine-protein kinase 2
著者Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
登録日2017-04-13
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP5
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Abl2 SH3 pTyr116/161
分子名称: Abelson tyrosine-protein kinase 2, SULFATE ION
著者Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
登録日2017-04-13
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
4EIK
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BU of 4eik by Molmil
Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12
分子名称: SODIUM ION, Tyrosine-protein kinase Fyn, VSL12 peptide
著者Camara-Artigas, A.
登録日2012-04-05
公開日2013-04-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex.
Acta Crystallogr F Struct Biol Commun, 72, 2016
8CHH
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BU of 8chh by Molmil
SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction method for spin-diffusion with PDB 2NUZ as reference
分子名称: Spectrin alpha chain, non-erythrocytic 1
著者Soeldner, B.
登録日2023-02-08
公開日2023-03-08
実験手法SOLID-STATE NMR
主引用文献Integrated Assessment of the Structure and Dynamics of Solid Proteins.
J Phys Chem Lett, 14, 2023
8CF4
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SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the combined correction method with PDB 2NUZ
分子名称: Spectrin alpha chain, non-erythrocytic 1
著者Soeldner, B.
登録日2023-02-02
公開日2023-03-08
実験手法SOLID-STATE NMR
主引用文献Integrated Assessment of the Structure and Dynamics of Solid Proteins.
J Phys Chem Lett, 14, 2023
8CHG
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BU of 8chg by Molmil
SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction for dipolar truncation with PDB 2NUZ
分子名称: Spectrin alpha chain, non-erythrocytic 1
著者Soeldner, B.
登録日2023-02-08
公開日2023-03-08
実験手法SOLID-STATE NMR
主引用文献Integrated Assessment of the Structure and Dynamics of Solid Proteins.
J Phys Chem Lett, 14, 2023
7TZK
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BU of 7tzk by Molmil
EPS8 SH3 Domain with NleH1 PxxDY Motif
分子名称: Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog
著者Grishin, A.M, Cygler, M.
登録日2022-02-15
公開日2022-07-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli
Proc.Natl.Acad.Sci.USA, 119, 2022
7TPB
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BU of 7tpb by Molmil
p120RasGAP SH3 domain in complex with DLC1 RhoGAP domain
分子名称: Ras GTPase-activating protein 1, Rho GTPase-activating protein 7
著者Stiegler, A.L, Boggon, T.J, Chau, J.E, Vish, K.J.
登録日2022-01-25
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP.
Nat Commun, 13, 2022
2F2W
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BU of 2f2w by Molmil
alpha-spectrin SH3 domain R21A mutant
分子名称: SULFATE ION, Spectrin alpha chain, brain
著者Camara-Artigas, A, Conejero-Lara, F, Casares, S, Lopez-Mayorga, O, Vega, C.
登録日2005-11-18
公開日2006-10-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain
Proteins, 67, 2007
2F2X
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alpha-spectrin SH3 domain R21G mutant
分子名称: SULFATE ION, Spectrin alpha chain, brain
著者Camara-Artigas, A, Conejero-Lara, F, Casares, S, Lopez-Mayorga, O, Vega, C.
登録日2005-11-18
公開日2006-10-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain
Proteins, 67, 2007
2EW3
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BU of 2ew3 by Molmil
Solution Structure Of The SH3 Domain Of Human SH3GL3
分子名称: SH3-containing GRB2-like protein 3
著者Gao, Y.G, Yan, X.Z, Hu, H.Y.
登録日2005-11-02
公開日2006-11-14
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural Basis for the Binding Specificities of Huntingtin Proline-Rich Region with SH3 and WW Domains
To be Published
7CFZ
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BU of 7cfz by Molmil
SH3 domain of NADPH oxidase activator 1
分子名称: NADPH oxidase activator 1
著者Kim, M, Park, J.H, Attri, P, Lee, W.
登録日2020-06-29
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural modification of NADPH oxidase activator (Noxa 1) by oxidative stress: An experimental and computational study.
Int.J.Biol.Macromol., 163, 2020
2FRY
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BU of 2fry by Molmil
Solution structure of the third SH3 domain of human NCK2 adaptor protein
分子名称: Cytoplasmic protein NCK2
著者Liu, J.
登録日2006-01-20
公開日2006-06-20
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural Insight into the Binding Diversity between the Human Nck2 SH3 Domains and Proline-Rich Proteins
Biochemistry, 45, 2006
3SEM
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BU of 3sem by Molmil
SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR
分子名称: SEX MUSCLE ABNORMAL PROTEIN 5, SH3 PEPTOID INHIBITOR
著者Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A.
登録日1998-11-02
公開日1999-01-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998
2YT6
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BU of 2yt6 by Molmil
Solution structure of the SH3_1 domain of Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
分子名称: Adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530076O17 product:Yamaguchi sarcoma viral (v-yes) oncogene homolog
著者Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2008-04-08
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3_1 domain of Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
To be Published
2YUO
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Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3
分子名称: RUN and TBC1 domain containing 3
著者Abe, H, Tochio, N, Miyamoto, K, Saito, K, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-06
公開日2007-10-09
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3
To be Published
5ZAU
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Complex of the human FYN SH3 and monobody binder
分子名称: Monobody Binder, Tyrosine-protein kinase Fyn
著者Reddy, P.P, Gulyani, A, Das, R.
登録日2018-02-09
公開日2019-09-11
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells.
Elife, 9, 2020
3H0H
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human Fyn SH3 domain R96I mutant, crystal form I
分子名称: Proto-oncogene tyrosine-protein kinase Fyn, TETRAETHYLENE GLYCOL
著者Dumas, C, Strub, M.-P, Arold, S.T.
登録日2009-04-09
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021

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件を2024-05-01に公開中

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