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7ZDE	IF(apo/as isolated) conformation of CydDC in AMP-PNP(CydD) bound state (Dataset-4) Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, MAGNESIUM ION, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZEC	IF(heme/confined) conformation of CydDC in ATP(CydD) bound state (Dataset-15) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-30 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZDL	IF(heme/coordinated) conformation of CydDC in AMP-PNP(CydC)/AMP-PNP(CydD) bound state (Dataset-8) Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, HEME B/C, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZDW	IF(heme/confined) conformation of CydDC mutant (E500Q.C) in AMP-PNP(CydD) bound state (Dataset-22) Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, HEME B/C, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZE5	Occ(apo/return) conformation of CydDC mutant (E500Q.C) in ATP(CydC)/AMP-PNP(CydD) bound state (Dataset-23) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-30 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (2.94 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZDK	IF(apo/asym) conformation of CydDC in AMP-PNP(CydC)/AMP-PNP(CydD) bound state (Dataset-8) Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, MAGNESIUM ION, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZDU	Occ(apo/return) conformation of CydDC mutant (E500Q.C) in ATP(CydC)/ATP(CydD) bound state (Dataset-19) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZDC	IF(heme/confined) conformation of CydDC in ADP(CydD) bound state (Dataset-3) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZD5	IF(apo/as isolated) conformation of CydDC (Dataset-1) Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
8BUU	ARE-ABCF VmlR2 bound to a 70S ribosome Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Crowe-McAuliffe, C, Wilson, D.N. Deposit date: 2022-11-30 Release date: 2023-04-05 Last modified: 2023-05-31 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR. Nucleic Acids Res., 51, 2023
7XEC	Cryo-EM structure of human ABCD1 E630Q in the presence of ATP in inward-facing state 2 Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1 Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-03-30 Release date: 2023-03-29 Method: ELECTRON MICROSCOPY (3.34 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
8FZQ	Dehosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION Authors: Levring, J, Terry, D.S, Kilic, Z, Fitzgerald, G.A, Blanchard, S.C, Chen, J. Deposit date: 2023-01-29 Release date: 2023-03-29 Last modified: 2023-05-03 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: CFTR function, pathology and pharmacology at single-molecule resolution. Nature, 616, 2023
7TDT	Cryo-EM structure of nanodisc-embedded human ABCA1 Descriptor: Phospholipid-transporting ATPase ABCA1 Authors: Plummer, A.M, Culbertson, A.T, Morales-Perez, C.L, Liao, M. Deposit date: 2022-01-03 Release date: 2023-03-29 Method: ELECTRON MICROSCOPY (4 Å) Cite: Activity and Structural Dynamics of Human ABCA1 in a Lipid Membrane. J.Mol.Biol., 435, 2023
8F4B	Bovine multidrug resistance protein 1 (MRP1) bound to cyclic peptide inhibitor 1 (CPI1) Descriptor: Cyclic peptide inhibitor 1 (CPI1), Multidrug resistance-associated protein 1 Authors: Pietz, H.L, Chen, J. Deposit date: 2022-11-10 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (3.27 Å) Cite: A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation. Proc.Natl.Acad.Sci.USA, 120, 2023
7X0T	Cryo-EM structure of human ABCD1 E630Q in the presence of C26:0-CoA and ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1, OCTANOYL-COENZYME A Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-02-22 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
7X0Z	Cryo-EM structure of human ABCD1 E630Q in the presence of ATP and Magnesium in outward-facing state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1, MAGNESIUM ION Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-02-22 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
7X07	Cryo-EM structure of human ABCD1 in the presence of C26:0 Descriptor: ATP-binding cassette sub-family D member 1, hexacosanoic acid Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-02-21 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (3.78 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
7X1W	Cryo-EM structure of human ABCD1 E630Q in the presence of ATP in inward-facing state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1 Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-02-24 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
7YRQ	Cryo-EM structure of human Peroxisomal ABC Transporter ABCD1 Descriptor: ATP-binding cassette sub-family D member 1, [(2~{R})-1-hexadecanoyloxy-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propan-2-yl] octadec-9-enoate Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-08-10 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
8FEF	Structure of Mce1 transporter from Mycobacterium smegmatis (Map0) Descriptor: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... Authors: Chen, J, Bhabha, G, Ekiert, D.C. Deposit date: 2022-12-06 Release date: 2023-02-22 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (2.71 Å) Cite: Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
8FED	Structure of Mce1-LucB complex from Mycobacterium smegmatis (Map1) Descriptor: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... Authors: Chen, J, Bhabha, G, Ekiert, D.C. Deposit date: 2022-12-06 Release date: 2023-02-22 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
8FEE	Structure of Mce1 transporter from Mycobacterium smegmatis in the absence of LucB (Map2) Descriptor: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... Authors: Chen, J, Bhabha, G, Ekiert, D.C. Deposit date: 2022-12-06 Release date: 2023-02-22 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
8FWK	CryoEM structure of Human ABCB6 Transporter Descriptor: ATP-binding cassette sub-family B member 6 Authors: Shaik, M.M, Myasnikov, A. Deposit date: 2023-01-22 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: CryoEM structure of Human ABCB6 Transporter To Be Published
7WIX	Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mycobactin import ATP-binding/permease protein IrtA, ... Authors: Zhang, B, Sun, S, Yang, H, Rao, Z. Deposit date: 2022-01-05 Release date: 2023-01-25 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.53 Å) Cite: Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023
7WIV	Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with an AMP-PNP Descriptor: Mycobactin import ATP-binding/permease protein IrtA, Mycobactin import ATP-binding/permease protein IrtB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Zhang, B, Sun, S, Yang, H, Rao, Z. Deposit date: 2022-01-05 Release date: 2023-01-25 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (2.88 Å) Cite: Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023

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