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6VXH
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BU of 6vxh by Molmil
Structure of ABCG2 bound to imatinib
分子名称: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL
著者Orlando, B.J, Liao, M.
登録日2020-02-21
公開日2020-05-13
最終更新日2020-05-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
6VXI
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BU of 6vxi by Molmil
Structure of ABCG2 bound to mitoxantrone
分子名称: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL
著者Orlando, B.J, Liao, M.
登録日2020-02-21
公開日2020-05-13
最終更新日2020-05-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
6UJT
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BU of 6ujt by Molmil
P-glycoprotein mutant-Y303A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJR
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BU of 6ujr by Molmil
P-glycoprotein mutant-F724A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJW
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BU of 6ujw by Molmil
P-glycoprotein mutant-Y306A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJP
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BU of 6ujp by Molmil
P-glycoprotein mutant-F979A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJS
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BU of 6ujs by Molmil
P-glycoprotein mutant-F728A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJN
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BU of 6ujn by Molmil
P-glycoprotein mutant-C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6P7F
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BU of 6p7f by Molmil
Human ABCC6 NBD2 R1459D mutant in Apo state
分子名称: Multidrug resistance-associated protein 6, SULFATE ION
著者Zheng, A, Thibodeau, P.H.
登録日2019-06-05
公開日2020-06-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.85004 Å)
主引用文献Structures of human ABCC6 NBD1 and NBD2
To Be Published
6UY0
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BU of 6uy0 by Molmil
Cryo-EM structure of wild-type bovine multidrug resistance protein 1 (MRP1) under active turnover conditions
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ...
著者Johnson, Z.L, Chen, J.
登録日2019-11-09
公開日2020-06-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses.
Elife, 9, 2020
6PAM
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BU of 6pam by Molmil
Structure of a bacterial Atm1-family ABC transporter with MgADP bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION
著者Fan, C, Kaiser, J.T, Rees, D.C.
登録日2019-06-11
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PAN
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BU of 6pan by Molmil
Structure of a bacterial Atm1-family ABC exporter with ATP bound
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATM1-type heavy metal exporter
著者Fan, C, Kaiser, J.T, Rees, D.C.
登録日2019-06-11
公開日2020-06-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PAQ
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BU of 6paq by Molmil
Structure of a bacterial Atm1-family ABC exporter with ATP bound
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATM1-type heavy metal exporter
著者Fan, C, Kaiser, J.T, Rees, D.C.
登録日2019-06-11
公開日2020-06-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PAO
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BU of 6pao by Molmil
Structure of a bacterial Atm1-family ABC exporter with ATP bound
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATM1-type heavy metal exporter
著者Fan, C, Kaiser, J.T, Rees, D.C.
登録日2019-06-11
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PAR
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BU of 6par by Molmil
Structure of a bacterial Atm1-family ABC exporter with MgAMPPNP bound
分子名称: ATM1-type heavy metal exporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Fan, C, Kaiser, J.T, Rees, D.C.
登録日2019-06-11
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XGZ
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BU of 6xgz by Molmil
Crystal structure of E. coli MlaFB ABC transport subunits in the monomeric state
分子名称: 1,2-ETHANEDIOL, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ...
著者Chang, Y, Bhabha, G, Ekiert, D.C.
登録日2020-06-18
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation.
Elife, 9, 2020
6VQU
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BU of 6vqu by Molmil
Structure of a bacterial Atm1-family ABC exporter
分子名称: ATM1-type heavy metal exporter
著者Fan, C, Rees, D.C.
登録日2020-02-05
公開日2020-07-29
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VQT
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BU of 6vqt by Molmil
Structure of a bacterial Atm1-family ABC exporter with MgADPVO4 bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION, ...
著者Fan, C, Rees, D.C.
登録日2020-02-05
公開日2020-07-29
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZME
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BU of 6zme by Molmil
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-02
公開日2020-08-12
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6Z4W
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BU of 6z4w by Molmil
FtsE structure from Streptococcus pneumoniae in complex with ADP (space group P 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE
著者Alcorlo, M, Straume, D, Hermoso, J.A, Havarstein, L.S.
登録日2020-05-26
公開日2020-09-02
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Structural Characterization of the Essential Cell Division Protein FtsE and Its Interaction with FtsX in Streptococcus pneumoniae.
Mbio, 11, 2020
6Z63
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BU of 6z63 by Molmil
FtsE structure from Streptococus pneumoniae in complex with ADP at 1.57 A resolution (spacegroup P 21)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE
著者Alcorlo, M, Straume, D, Havarstein, L.S, Hermoso, J.A.
登録日2020-05-27
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structural Characterization of the Essential Cell Division Protein FtsE and Its Interaction with FtsX in Streptococcus pneumoniae.
Mbio, 11, 2020
6Z67
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BU of 6z67 by Molmil
FtsE structure of Streptococcus pneumoniae in complex with AMPPNP at 2.4 A resolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Alcorlo, M, Straume, D, Havarstein, L.S, Hermoso, j.A.
登録日2020-05-28
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Characterization of the Essential Cell Division Protein FtsE and Its Interaction with FtsX in Streptococcus pneumoniae.
Mbio, 11, 2020
7CGN
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BU of 7cgn by Molmil
The overall structure of the MlaFEDB complex in ATP-bound EQtall conformation (Mutation of E170Q on MlaF)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ...
著者Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y.
登録日2020-07-01
公開日2020-09-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural mechanism of phospholipids translocation by MlaFEDB complex.
Cell Res., 30, 2020
7CGE
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BU of 7cge by Molmil
The overall structure of nucleotide free MlaFEDB complex
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ...
著者Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y.
登録日2020-07-01
公開日2020-09-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural mechanism of phospholipids translocation by MlaFEDB complex.
Cell Res., 30, 2020
7CH0
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BU of 7ch0 by Molmil
The overall structure of the MlaFEDB complex in ATP-bound EQclose conformation (Mutation of E170Q on MlaF)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ...
著者Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y.
登録日2020-07-03
公開日2020-09-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural mechanism of phospholipids translocation by MlaFEDB complex.
Cell Res., 30, 2020

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