PDB: 866 件ウェブページステータス検索Chemie searchBIRD

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5YV5	Crystal structure of the complex of archaeal ribosomal stalk protein aP1 and archaeal ribosome recycling factor aABCE1. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase RIL, Archaeal ribosomal stalk protein aP1, ... 著者 Imai, H, Abe, T, Miyoshi, T, Nishikawa, S, Ito, K, Uchiumi, T. 登録日 2017-11-24 公開日 2018-07-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The ribosomal stalk protein is crucial for the action of the conserved ATPase ABCE1 Nucleic Acids Res., 46, 2018
6BPP	E. coli MsbA in complex with LPS and inhibitor G092 分子名称: (2E)-3-{6-[(1S)-1-(3-amino-2,6-dichlorophenyl)ethoxy]-4-cyclopropylquinolin-3-yl}prop-2-enoic acid, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 3-HYDROXY-TETRADECANOIC ACID, ... 著者 Ho, H, Koth, C.M, Payandeh, J. 登録日 2017-11-24 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Structural basis for dual-mode inhibition of the ABC transporter MsbA. Nature, 557, 2018
5YWC	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW9	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A) 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWB	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-30 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW8	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A) 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWD	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (focused refinement of SUR1 ABC transporter module at 4.22A) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, MAGNESIUM ION 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW7	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A) 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWA	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A) 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
6BZR	Human ABCC6 NBD2 in ADP-bound state 分子名称: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Multidrug resistance-associated protein 6 著者 Zheng, A, Thibodeau, P.H. 登録日 2017-12-25 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.79999447 Å) 主引用文献 Structures of human ABCC6 NBD1 and NBD2 To Be Published
6BZS	Human ABCC6 NBD1 in Apo state 分子名称: Multidrug resistance-associated protein 6, SULFATE ION 著者 Zheng, A, Thibodeau, P.H. 登録日 2017-12-26 公開日 2018-09-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.29990458 Å) 主引用文献 Structural analysis reveals pathomechanisms associated with pseudoxanthoma elasticum-causing mutations in the ABCC6 transporter. J. Biol. Chem., 293, 2018
6C0V	Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance protein 1 著者 Kim, Y.J, Chen, J. 登録日 2018-01-02 公開日 2018-01-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation. Science, 359, 2018
6FEQ	Structure of inhibitor-bound ABCG2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... 著者 Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. 登録日 2018-01-03 公開日 2018-04-11 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
6FFC	Structure of an inhibitor-bound ABC transporter 分子名称: ATP-binding cassette sub-family G member 2, ~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate 著者 Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. 登録日 2018-01-06 公開日 2018-04-11 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
6C3O	Cryo-EM structure of human KATP bound to ATP and ADP in quatrefoil form 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... 著者 Lee, K.P.K, Chen, J, MacKinnon, R. 登録日 2018-01-10 公開日 2018-01-31 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular structure of human KATP in complex with ATP and ADP Elife, 6, 2017
6C3P	Cryo-EM structure of human KATP bound to ATP and ADP in propeller form 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... 著者 Lee, K.P.K, Chen, J, MacKinnon, R. 登録日 2018-01-10 公開日 2018-01-24 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Molecular structure of human KATP in complex with ATP and ADP. Elife, 6, 2017
6FN1	Zosuquidar and UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Human-mouse chimeric ABCB1 (ABCBHM), UIC2 Antigen Binding Fragment Heavy Chain, ... 著者 Alam, A, Locher, K.P. 登録日 2018-02-02 公開日 2018-02-21 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FN4	Apo form of UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Apo form of Human-mouse chimeric ABCB1 (ABCB1HM) in complex with Antigen binding fragment of UIC2., ... 著者 Alam, A, Locher, K.P. 登録日 2018-02-02 公開日 2018-02-21 最終更新日 2021-06-02 実験手法 ELECTRON MICROSCOPY (4.14 Å) 主引用文献 Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FNP	Crystal structure of ECF-CbrT, a cobalamin transporter 分子名称: Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... 著者 Santos, J.A, Rempel, S, Guskov, A, Slotboom, D.J. 登録日 2018-02-05 公開日 2018-07-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Functional and structural characterization of an ECF-type ABC transporter for vitamin B12. Elife, 7, 2018
6CVL	Crystal structure of the Escherichia coli ATPgS-bound MetNI methionine ABC transporter in complex with its MetQ binding protein 分子名称: IODIDE ION, MERCURY (II) ION, MetI transmembrane subunit, ... 著者 Nguyen, P.T, Kaiser, J.T, Rees, D.C. 登録日 2018-03-28 公開日 2018-11-14 最終更新日 2022-04-27 実験手法 X-RAY DIFFRACTION (2.953 Å) 主引用文献 Noncanonical role for the binding protein in substrate uptake by the MetNI methionine ATP Binding Cassette (ABC) transporter. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ZLU	Ribosome Structure bound to ABC-F protein. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Su, W.X, Kumar, V, Ero, R, Andrew, S.W.W, Jian, S, Yong-Gui, G. 登録日 2018-03-29 公開日 2018-08-01 最終更新日 2019-12-04 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Ribosome protection by antibiotic resistance ATP-binding cassette protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6D3S	Thermostabilized phosphorylated chicken CFTR 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator 著者 Fay, J.F, Riordan, J.R, Chen, Z.J. 登録日 2018-04-16 公開日 2018-10-17 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel. Biochemistry, 57, 2018
6GDI	Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state 分子名称: Multidrug resistance protein 1A 著者 Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A. 登録日 2018-04-23 公開日 2018-05-23 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution. Bmc Struct.Biol., 18, 2018
6GJQ	human NBD1 of CFTR in complex with nanobody T27 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, Nanobody T27 著者 Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. 登録日 2018-05-16 公開日 2019-06-19 最終更新日 2019-08-21 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
6GJS	Human NBD1 of CFTR in complex with nanobodies D12 and T4 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ... 著者 Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. 登録日 2018-05-16 公開日 2019-06-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019

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