PDB: 55 resultsInfo pagesStatus searchChemie searchBIRD

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8HKW	Crystal structure of importin-alpha3 bound to the 53BP1 nuclear localization signal Descriptor: Importin subunit alpha-3, Peptide from TP53-binding protein 1 Authors: Matsuura, Y. Deposit date: 2022-11-28 Release date: 2022-12-21 Last modified: 2023-03-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystallographic data of an importin-alpha 3 dimer in which the two protomers are bridged by a bipartite nuclear localization signal. Data Brief, 47, 2023
3GJ0	Crystal structure of human RanGDP Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION Authors: Partridge, J.R, Schwartz, T.U. Deposit date: 2009-03-07 Release date: 2009-08-04 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Crystallographic and Biochemical Analysis of the Ran-binding Zinc Finger Domain. J.Mol.Biol., 391, 2009
4U0B	Hexamer HIV-1 CA in complex with CPSF6 peptide, P212121 crystal form Descriptor: Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6 Authors: Price, A.J, Jacques, D.A, James, L.C. Deposit date: 2014-07-11 Release date: 2014-11-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly. Plos Pathog., 10, 2014
4U0A	Hexameric HIV-1 CA in complex with CPSF6 peptide, P6 crystal form Descriptor: CHLORIDE ION, Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6 Authors: Price, A.J, Jacques, D.A, James, L.C. Deposit date: 2014-07-11 Release date: 2014-11-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly. Plos Pathog., 10, 2014
4U0E	Hexameric HIV-1 CA in complex with PF3450074 Descriptor: CHLORIDE ION, Capsid protein p24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE Authors: Price, A.J, Jacques, D.A, James, L.C. Deposit date: 2014-07-11 Release date: 2014-11-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.043 Å) Cite: Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly. Plos Pathog., 10, 2014
4U0F	Hexameric HIV-1 CA in Complex with BI-2 Descriptor: (4S)-4-(4-hydroxyphenyl)-3-phenyl-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one, 1,2-ETHANEDIOL, Capsid protein p24 Authors: Price, A.J, Jacques, D.A, James, L.C. Deposit date: 2014-07-11 Release date: 2014-11-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly. Plos Pathog., 10, 2014
2Q5D	Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form Descriptor: Importin beta-1 subunit, Snurportin-1 Authors: Mitrousis, G, Cingolani, G. Deposit date: 2007-05-31 Release date: 2008-01-22 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}. J.Biol.Chem., 283, 2008
7SNQ	Hexamer HIV-1 CA in complex with CPSF6 peptide and IP6 ligand Descriptor: CHLORIDE ION, Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, ... Authors: Bester, S.M, Kvaratskhelia, M. Deposit date: 2021-10-28 Release date: 2022-09-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection. Nat Commun, 13, 2022
4WYM	Structural basis of HIV-1 capsid recognition by CPSF6 Descriptor: Capsid protein p24, ISOFORM 2 OF CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6 Authors: Battacharya, A, Taylor, A.B, Hart, P.J, Ivanov, D.N. Deposit date: 2014-11-17 Release date: 2014-12-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis of HIV-1 capsid recognition by PF74 and CPSF6. Proc.Natl.Acad.Sci.USA, 111, 2014
2P8Q	Crystal Structure of human Importin beta bound to the Snurportin1 IBB-domain Descriptor: Importin beta-1 subunit, Snurportin-1 Authors: Mitrousis, G, Cingolani, G. Deposit date: 2007-03-22 Release date: 2008-01-22 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}. J.Biol.Chem., 283, 2008
4QNB	Disulfide stabilized HIV-1 CA hexamer in complex with PHENYL-L-PHENYLALANINAMIDE inhibitor Descriptor: CAPSID PROTEIN P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE Authors: Pornillos, O. Deposit date: 2014-06-17 Release date: 2014-12-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.996 Å) Cite: Structural basis of HIV-1 capsid recognition by PF74 and CPSF6. Proc.Natl.Acad.Sci.USA, 111, 2014
4DHX	ENY2:GANP complex Descriptor: 80 kDa MCM3-associated protein, Enhancer of yellow 2 transcription factor homolog Authors: Stewart, M, Jani, D. Deposit date: 2012-01-30 Release date: 2012-06-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export. Nucleic Acids Res., 40, 2012
6VKV	Co-crystal structure of GS-6207 bound to HIV-1 capsid hexamer Descriptor: CHLORIDE ION, Capsid protein p24, IODIDE ION, ... Authors: Bester, S.M, Kvaratskhelia, M. Deposit date: 2020-01-22 Release date: 2020-10-21 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Structural and mechanistic bases for a potent HIV-1 capsid inhibitor. Science, 370, 2020
6VWS	Hexamer of Helical HIV capsid by RASTR method Descriptor: HIV capsid protein Authors: Zhao, H, Iqbal, N, Asturias, F, Kvaratskhelia, M, Vanblerkom, P. Deposit date: 2020-02-20 Release date: 2020-10-21 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (6.08 Å) Cite: Structural and mechanistic bases for a potent HIV-1 capsid inhibitor. Science, 370, 2020
2K1P	Solution structure of the second zinc finger domain of ZRANB2/ZNF265 Descriptor: ZINC ION, Zinc finger Ran-binding domain-containing protein 2 Authors: Loughlin, F.E, Mackay, J.P. Deposit date: 2008-03-13 Release date: 2009-03-17 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: The zinc fingers of the SR-proein ZRANB2 recognize 5'splice site-like sequences and constitute a distinct class of RNA binding domain To be Published
4XRO	Disulfide stabilized HIV-1 CA hexamer 4mut (S41A, Q67H, V165I, L172I) Descriptor: Capsid protein p24 Authors: Price, A.J, James, L.C. Deposit date: 2015-01-21 Release date: 2015-07-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.01 Å) Cite: HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry. J.Virol., 89, 2015
4XRQ	Disulfide stabilized HIV-1 CA hexamer 4mut (S41A, Q67H, V165I, L172I) in complex with PF-3450074 Descriptor: Capsid protein p24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE Authors: Price, A.J, James, L.C. Deposit date: 2015-01-21 Release date: 2015-07-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.95 Å) Cite: HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry. J.Virol., 89, 2015
6AY9	Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide Descriptor: CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein, ... Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
6B2K	E45A/R132T mutant of HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-20 Release date: 2018-09-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
6B2J	E45A mutant of HIV-1 capsid protein (other crystal form) Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-20 Release date: 2018-09-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
6B2I	E45A mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-20 Release date: 2018-09-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
6B2G	P38A mutant of HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-20 Release date: 2018-09-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.407 Å) Cite: Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
6B2H	P38A/T216I mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-20 Release date: 2018-09-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
8CKV	HIV-1 mature capsid hexamer from CA-IP6 CLPs Descriptor: Gag polyprotein Authors: Stacey, J.C.V, Briggs, J.A.G. Deposit date: 2023-02-16 Release date: 2023-04-26 Method: ELECTRON MICROSCOPY (2.89 Å) Cite: Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding. Proc.Natl.Acad.Sci.USA, 120, 2023
8CKW	HIV-1 mature capsid pentamer from CA-IP6 CLPs Descriptor: Gag polyprotein Authors: Stacey, J.C.V, Briggs, J.A.G. Deposit date: 2023-02-16 Release date: 2023-04-26 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding. Proc.Natl.Acad.Sci.USA, 120, 2023

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