PDB: 44643 件ウェブページステータス検索Chemie searchBIRD

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8QNI	Crystal structure of the E3 ubiquitin ligase Cbl-b with an allosteric inhibitor (benzodiazepine compound 25) 分子名称: 2-[[(2~{S})-2-methylmorpholin-4-yl]methyl]-~{N}-[(3~{S})-2-oxidanylidene-5-phenyl-1,3-dihydropyrido[3,4-e][1,4]diazepin-3-yl]benzamide, E3 ubiquitin-protein ligase CBL-B, SODIUM ION, ... 著者 Schimpl, M. 登録日 2023-09-26 公開日 2023-11-22 最終更新日 2024-01-03 実験手法 X-RAY DIFFRACTION (2.483 Å) 主引用文献 Discovery of a Novel Benzodiazepine Series of Cbl-b Inhibitors for the Enhancement of Antitumor Immunity. Acs Med.Chem.Lett., 14, 2023
8UCG	Thermophilic RNA Ligase from Palaeococcus pacificus K92A 分子名称: ATP dependent DNA ligase, GLYCEROL, MAGNESIUM ION, ... 著者 Rousseau, M.D, Hicks, J.L, Oulavallickal, T, Williamson, A, Arcus, V.L, Patrick, M.W. 登録日 2023-09-26 公開日 2024-02-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus. Nucleic Acids Res., 52, 2024
8UCH	Thermophilic RNA Ligase from Palaeococcus pacificus K92A + ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP dependent DNA ligase, GLYCEROL, ... 著者 Rousseau, M.D, Hicks, J.L, Oulavallickal, T, Williamson, A, Arcus, V.L, Patrick, M.W. 登録日 2023-09-26 公開日 2024-02-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus. Nucleic Acids Res., 52, 2024
8WI7	Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, bS1 and RafH. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Kumar, N, Sharma, S, Kaushal, P.S. 登録日 2023-09-24 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8WIB	Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, E- tRNA and RafH. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Kumar, N, Sharma, S, Kaushal, P.S. 登録日 2023-09-24 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8WHX	Cryo- EM structure of Mycobacterium smegmatis 70S ribosome and RafH. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Kumar, N, Sharma, S, Kaushal, P.S. 登録日 2023-09-23 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8WGV	BA.2(S375) Spike (S6P)/hACE2 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... 著者 Wei, X, Zhang, Z. 登録日 2023-09-22 公開日 2024-02-28 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis. Nat.Immunol., 25, 2024
8QMG	Tobacco lectin Nictaba in apo state including I and Eu SAD datasets. 分子名称: Nictaba, ZINC ION 著者 Bloch, Y, Savvides, S.N. 登録日 2023-09-22 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Tobacco lectin Nictaba in apo state including I and Eu SAD datasets. To Be Published
8QMI	Crystal structure of RNA G2C4 repeats - native model 分子名称: MAGNESIUM ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3') 著者 Blaszczyk, L, Kiliszek, A. 登録日 2023-09-22 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Antisense RNA C9orf72 Hexanucleotide Repeat Associated With ALS/FTD Forms A Triplex-Like Structure and Binds Small Synthetic Molecule ANP77 To Be Published
8QMH	Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77 分子名称: 3-(7-azanyl-1,8-naphthyridin-2-yl)-2-[(7-azanyl-1,8-naphthyridin-2-yl)methyl]-~{N}-(3-azanylpropyl)propanamide, CHLORIDE ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3') 著者 Kiliszek, A, Ryczek, M, Blaszczyk, L. 登録日 2023-09-22 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Antisense RNA C9orf72 Hexanucleotide Repeat Associated With ALS/FTD Forms A Triplex-Like Structure and Binds Small Synthetic Molecule ANP77 To Be Published
8QM3	formaldehyde-inhibited [FeFe]-hydrogenase I from Clostridium pasteurianum (CpI) 分子名称: CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, FORMYL GROUP, ... 著者 Duan, J, Hofmann, E. 登録日 2023-09-21 公開日 2023-11-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Insights into the Molecular Mechanism of Formaldehyde Inhibition of [FeFe]-Hydrogenases. J.Am.Chem.Soc., 145, 2023
8UAF	E. coli Sir2_HerA complex (12:6) bound with NAD+ 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Shen, Z.F, Lin, Q.P, Fu, T.M. 登録日 2023-09-20 公開日 2023-12-27 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83, 2023
8UAE	E. coli Sir2_HerA complex (12:6) with ATPgamaS 分子名称: MAGNESIUM ION, Nucleoside triphosphate hydrolase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Shen, Z.F, Lin, Q.P, Fu, T.M. 登録日 2023-09-20 公開日 2023-12-27 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83, 2023
8WFV	Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum (Data 3) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, SODIUM ION 著者 Nam, K.H. 登録日 2023-09-20 公開日 2023-10-04 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Conformational Change of the L3 Loop Affects the Structural Changes in the Substrate Binding Pocket Entrance of beta-Glucosidase. Molecules, 28, 2023
8WFT	Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum (Data 1) 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, ... 著者 Nam, K.H. 登録日 2023-09-20 公開日 2023-10-04 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Conformational Change of the L3 Loop Affects the Structural Changes in the Substrate Binding Pocket Entrance of beta-Glucosidase. Molecules, 28, 2023
8WFU	Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum (Data 2) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, SODIUM ION 著者 Nam, K.H. 登録日 2023-09-20 公開日 2023-10-04 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Conformational Change of the L3 Loop Affects the Structural Changes in the Substrate Binding Pocket Entrance of beta-Glucosidase. Molecules, 28, 2023
8WFW	Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum (Data 4) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, SODIUM ION 著者 Nam, K.H. 登録日 2023-09-20 公開日 2023-10-04 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 The Conformational Change of the L3 Loop Affects the Structural Changes in the Substrate Binding Pocket Entrance of beta-Glucosidase. Molecules, 28, 2023
8WFY	The Crystal Structure of SHP2 from Biortus. 分子名称: 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11 著者 Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. 登録日 2023-09-20 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Crystal Structure of SHP2 from Biortus. To Be Published
8WFJ	human glycine transporter 1 in complex with ALX-5407 in inward facing conformation 分子名称: ALX5407, Sodium- and chloride-dependent glycine transporter 1 著者 Wei, Y, Zhao, Y. 登録日 2023-09-19 公開日 2024-04-03 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Transport mechanism and pharmacology of the human GlyT1. Cell, 187, 2024
8WFK	human glycine transporter 1 in complex with SSR504734 in outward facing conformation 分子名称: CHLORIDE ION, SODIUM ION, SSR504734, ... 著者 Wei, Y, Zhao, Y. 登録日 2023-09-19 公開日 2024-04-03 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.22 Å) 主引用文献 Transport mechanism and pharmacology of the human GlyT1. Cell, 187, 2024
8WFL	human glycine transporter 1 in complex with PF-03463275 in outward facing conformation 分子名称: PF-3463275, Sodium- and chloride-dependent glycine transporter 1 著者 Wei, Y, Zhao, Y. 登録日 2023-09-19 公開日 2024-04-03 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Transport mechanism and pharmacology of the human GlyT1. Cell, 187, 2024
8WFI	human glycine transporter 1 in complex with glycine in occluded conformation 分子名称: CHLORIDE ION, GLYCINE, Isoform GlyT-1B of Sodium- and chloride-dependent glycine transporter 1, ... 著者 Wei, Y, Zhao, Y. 登録日 2023-09-19 公開日 2024-04-03 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Transport mechanism and pharmacology of the human GlyT1. Cell, 187, 2024
8WEY	PSI-LHCI of the red alga Cyanidium caldarium RK-1 (NIES-2137) 分子名称: (1~{R})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{R} )-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ... 著者 Kato, K, Hamaguchi, T, Nakajima, Y, Kawakami, K, Yonekura, K, Shen, J.R, Nagao, R. 登録日 2023-09-19 公開日 2024-02-14 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (1.92 Å) 主引用文献 The structure of PSI-LHCI from Cyanidium caldarium provides evolutionary insights into conservation and diversity of red-lineage LHCs. Proc.Natl.Acad.Sci.USA, 121, 2024
8U90	Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, hexagonal form) 分子名称: CHLORIDE ION, GLYCEROL, IODIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-18 公開日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, hexagonal form) To be published
8U92	Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound, Orthorhombic P form) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-18 公開日 2023-09-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound, Orthorhombic P form) To be published

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