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8QNI
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BU of 8qni by Molmil
Crystal structure of the E3 ubiquitin ligase Cbl-b with an allosteric inhibitor (benzodiazepine compound 25)
Descriptor: 2-[[(2~{S})-2-methylmorpholin-4-yl]methyl]-~{N}-[(3~{S})-2-oxidanylidene-5-phenyl-1,3-dihydropyrido[3,4-e][1,4]diazepin-3-yl]benzamide, E3 ubiquitin-protein ligase CBL-B, SODIUM ION, ...
Authors:Schimpl, M.
Deposit date:2023-09-26
Release date:2023-11-22
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (2.483 Å)
Cite:Discovery of a Novel Benzodiazepine Series of Cbl-b Inhibitors for the Enhancement of Antitumor Immunity.
Acs Med.Chem.Lett., 14, 2023
8UCG
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BU of 8ucg by Molmil
Thermophilic RNA Ligase from Palaeococcus pacificus K92A
Descriptor: ATP dependent DNA ligase, GLYCEROL, MAGNESIUM ION, ...
Authors:Rousseau, M.D, Hicks, J.L, Oulavallickal, T, Williamson, A, Arcus, V.L, Patrick, M.W.
Deposit date:2023-09-26
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus.
Nucleic Acids Res., 52, 2024
8UCH
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BU of 8uch by Molmil
Thermophilic RNA Ligase from Palaeococcus pacificus K92A + ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP dependent DNA ligase, GLYCEROL, ...
Authors:Rousseau, M.D, Hicks, J.L, Oulavallickal, T, Williamson, A, Arcus, V.L, Patrick, M.W.
Deposit date:2023-09-26
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus.
Nucleic Acids Res., 52, 2024
8WI7
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BU of 8wi7 by Molmil
Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, bS1 and RafH.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Kumar, N, Sharma, S, Kaushal, P.S.
Deposit date:2023-09-24
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
8WIB
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BU of 8wib by Molmil
Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, E- tRNA and RafH.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Kumar, N, Sharma, S, Kaushal, P.S.
Deposit date:2023-09-24
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
8WHX
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BU of 8whx by Molmil
Cryo- EM structure of Mycobacterium smegmatis 70S ribosome and RafH.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Kumar, N, Sharma, S, Kaushal, P.S.
Deposit date:2023-09-23
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
8WGV
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BU of 8wgv by Molmil
BA.2(S375) Spike (S6P)/hACE2 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Wei, X, Zhang, Z.
Deposit date:2023-09-22
Release date:2024-02-28
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.
Nat.Immunol., 25, 2024
8QMG
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BU of 8qmg by Molmil
Tobacco lectin Nictaba in apo state including I and Eu SAD datasets.
Descriptor: Nictaba, ZINC ION
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2023-09-22
Release date:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Tobacco lectin Nictaba in apo state including I and Eu SAD datasets.
To Be Published
8QMI
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BU of 8qmi by Molmil
Crystal structure of RNA G2C4 repeats - native model
Descriptor: MAGNESIUM ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3')
Authors:Blaszczyk, L, Kiliszek, A.
Deposit date:2023-09-22
Release date:2024-05-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Antisense RNA C9orf72 Hexanucleotide Repeat Associated With ALS/FTD Forms A Triplex-Like Structure and Binds Small Synthetic Molecule ANP77
To Be Published
8QMH
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BU of 8qmh by Molmil
Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77
Descriptor: 3-(7-azanyl-1,8-naphthyridin-2-yl)-2-[(7-azanyl-1,8-naphthyridin-2-yl)methyl]-~{N}-(3-azanylpropyl)propanamide, CHLORIDE ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3')
Authors:Kiliszek, A, Ryczek, M, Blaszczyk, L.
Deposit date:2023-09-22
Release date:2024-05-01
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Antisense RNA C9orf72 Hexanucleotide Repeat Associated With ALS/FTD Forms A Triplex-Like Structure and Binds Small Synthetic Molecule ANP77
To Be Published
8QM3
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BU of 8qm3 by Molmil
formaldehyde-inhibited [FeFe]-hydrogenase I from Clostridium pasteurianum (CpI)
Descriptor: CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, FORMYL GROUP, ...
Authors:Duan, J, Hofmann, E.
Deposit date:2023-09-21
Release date:2023-11-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Insights into the Molecular Mechanism of Formaldehyde Inhibition of [FeFe]-Hydrogenases.
J.Am.Chem.Soc., 145, 2023
8UAF
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BU of 8uaf by Molmil
E. coli Sir2_HerA complex (12:6) bound with NAD+
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Shen, Z.F, Lin, Q.P, Fu, T.M.
Deposit date:2023-09-20
Release date:2023-12-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
8UAE
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BU of 8uae by Molmil
E. coli Sir2_HerA complex (12:6) with ATPgamaS
Descriptor: MAGNESIUM ION, Nucleoside triphosphate hydrolase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Shen, Z.F, Lin, Q.P, Fu, T.M.
Deposit date:2023-09-20
Release date:2023-12-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
8WFV
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BU of 8wfv by Molmil
Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum (Data 3)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, SODIUM ION
Authors:Nam, K.H.
Deposit date:2023-09-20
Release date:2023-10-04
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Conformational Change of the L3 Loop Affects the Structural Changes in the Substrate Binding Pocket Entrance of beta-Glucosidase.
Molecules, 28, 2023
8WFT
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BU of 8wft by Molmil
Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum (Data 1)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, ...
Authors:Nam, K.H.
Deposit date:2023-09-20
Release date:2023-10-04
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Conformational Change of the L3 Loop Affects the Structural Changes in the Substrate Binding Pocket Entrance of beta-Glucosidase.
Molecules, 28, 2023
8WFU
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BU of 8wfu by Molmil
Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum (Data 2)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, SODIUM ION
Authors:Nam, K.H.
Deposit date:2023-09-20
Release date:2023-10-04
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Conformational Change of the L3 Loop Affects the Structural Changes in the Substrate Binding Pocket Entrance of beta-Glucosidase.
Molecules, 28, 2023
8WFW
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BU of 8wfw by Molmil
Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum (Data 4)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, SODIUM ION
Authors:Nam, K.H.
Deposit date:2023-09-20
Release date:2023-10-04
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:The Conformational Change of the L3 Loop Affects the Structural Changes in the Substrate Binding Pocket Entrance of beta-Glucosidase.
Molecules, 28, 2023
8WFY
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BU of 8wfy by Molmil
The Crystal Structure of SHP2 from Biortus.
Descriptor: 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11
Authors:Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J.
Deposit date:2023-09-20
Release date:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of SHP2 from Biortus.
To Be Published
8WFJ
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BU of 8wfj by Molmil
human glycine transporter 1 in complex with ALX-5407 in inward facing conformation
Descriptor: ALX5407, Sodium- and chloride-dependent glycine transporter 1
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFK
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BU of 8wfk by Molmil
human glycine transporter 1 in complex with SSR504734 in outward facing conformation
Descriptor: CHLORIDE ION, SODIUM ION, SSR504734, ...
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFL
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BU of 8wfl by Molmil
human glycine transporter 1 in complex with PF-03463275 in outward facing conformation
Descriptor: PF-3463275, Sodium- and chloride-dependent glycine transporter 1
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFI
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BU of 8wfi by Molmil
human glycine transporter 1 in complex with glycine in occluded conformation
Descriptor: CHLORIDE ION, GLYCINE, Isoform GlyT-1B of Sodium- and chloride-dependent glycine transporter 1, ...
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WEY
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BU of 8wey by Molmil
PSI-LHCI of the red alga Cyanidium caldarium RK-1 (NIES-2137)
Descriptor: (1~{R})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{R} )-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ...
Authors:Kato, K, Hamaguchi, T, Nakajima, Y, Kawakami, K, Yonekura, K, Shen, J.R, Nagao, R.
Deposit date:2023-09-19
Release date:2024-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (1.92 Å)
Cite:The structure of PSI-LHCI from Cyanidium caldarium provides evolutionary insights into conservation and diversity of red-lineage LHCs.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U90
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BU of 8u90 by Molmil
Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, hexagonal form)
Descriptor: CHLORIDE ION, GLYCEROL, IODIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-18
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, hexagonal form)
To be published
8U92
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BU of 8u92 by Molmil
Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound, Orthorhombic P form)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-18
Release date:2023-09-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound, Orthorhombic P form)
To be published

219869

数据于2024-05-15公开中

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