PDB: 44484 resultsInfo pagesStatus searchChemie searchBIRD

---

8WAO	Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II positioned 5nt downstream of TSS. Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... Authors: Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. Deposit date: 2023-09-07 Release date: 2023-12-06 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (6.4 Å) Cite: Structural visualization of transcription initiation in action. Science, 382, 2023
8WAN	Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS. Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... Authors: Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. Deposit date: 2023-09-07 Release date: 2023-12-06 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (6.07 Å) Cite: Structural visualization of transcription initiation in action. Science, 382, 2023
8QGW	Crystal structure of oxidized respiratory Complex I subunits NuoEF from Aquifex aeolicus bound to oxidized 3-acetylpyridine adenine dinucleotide Descriptor: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ... Authors: Wohlwend, D, Friedrich, T. Deposit date: 2023-09-06 Release date: 2024-04-03 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structures of 3-acetylpyridine adenine dinucleotide and ADP-ribose bound to the electron input module of respiratory complex I. Structure, 2024
8QH4	Crystal structure of reduced respiratory Complex I subunits NuoEF from Aquifex aeolicus bound to oxidized 3-acetylpyridine adenine dinucleotide Descriptor: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, ... Authors: Wohlwend, D, Friedrich, T. Deposit date: 2023-09-06 Release date: 2024-04-03 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structures of 3-acetylpyridine adenine dinucleotide and ADP-ribose bound to the electron input module of respiratory complex I. Structure, 2024
8QH7	Crystal structure of respiratory Complex I subunits NuoEF from Aquifex aeolicus bound to reduced 3-acetylpyridine adenine dinucleotide (without reducing agent) Descriptor: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYL PYRIDINE ADENINE DINUCLEOTIDE, ... Authors: Wohlwend, D, Friedrich, T. Deposit date: 2023-09-06 Release date: 2024-04-03 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structures of 3-acetylpyridine adenine dinucleotide and ADP-ribose bound to the electron input module of respiratory complex I. Structure, 2024
8U2Q	Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) Descriptor: 1,2-ETHANEDIOL, 5'-O-(glycylsulfamoyl)adenosine, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-09-06 Release date: 2023-09-13 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) To be published
8U2S	Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (Ethyl AMP bound, P21 form) Descriptor: 5'-O-[(S)-ethoxy(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase, CACODYLATE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-09-06 Release date: 2023-09-13 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (Ethyl AMP bound, P21 form) To be published
8U2M	Structure of P450Blt from Micromonospora sp. MW-13 in Complex with Biarylitide Descriptor: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, ACETATE ION, Cytochrome P450-SU1, ... Authors: Hansen, M.H, Cryle, M.J. Deposit date: 2023-09-06 Release date: 2024-01-10 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis Acs Catalysis, 2024
8WA2	cryo-EM structure of native mastigonemes isolated from Chlamydomonas reinhardtii at 3.0 angstrom resolution Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Huang, J, Tao, H, Chen, J, Pan, J, Yan, C, Yan, N. Deposit date: 2023-09-06 Release date: 2024-04-10 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure-guided discovery of protein and glycan components in native mastigonemes Cell(Cambridge,Mass.), 2024
8QG1	Crystal structure of oxidized respiratory Complex I subunits NuoEF from Aquifex aeolicus bound to ADP-ribose Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5-DIPHOSPHORIBOSE, CHLORIDE ION, ... Authors: Wohlwend, D, Friedrich, T. Deposit date: 2023-09-05 Release date: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Structures of 3-acetylpyridine adenine dinucleotide and ADP-ribose bound to the electron input module of respiratory complex I. Structure, 2024
8U28	Gaussian mixture model based single particle refinement - SARS (SARS-CoV-2 Spike Proteins on intact virions from EMPIAR-10492) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Chen, M, Pintilie, G. Deposit date: 2023-09-05 Release date: 2023-11-15 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nat.Methods, 21, 2024
8U29	Prefusion structure of the PRD-0038 spike glycoprotein ectodomain trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRD-0038 Spike glycoprotein, ... Authors: Lee, J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-09-05 Release date: 2023-12-06 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus. Cell Host Microbe, 31, 2023
8U2D	Bruton's tyrosine kinase in complex with N-[(2R)-1-[(3R)-3-(methylcarbamoyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-yl]-3-(3-methylphenyl)-1-oxopropan-2-yl]-1H-indazole-5-carboxamide Descriptor: (3R)-2-[N-(1H-indazole-5-carbonyl)-3-methyl-D-phenylalanyl]-N-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Gajewski, S, Clifton, M.C. Deposit date: 2023-09-05 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies. J.Med.Chem., 67, 2024
8W9N	Structure of AtHKT1;1 in NaCl at 2.7 Angstroms resolution Descriptor: SODIUM ION, Sodium transporter HKT1 Authors: Wang, J.Q. Deposit date: 2023-09-05 Release date: 2024-02-14 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structure of AtHKT1;1 in NaCl at 2.7 Angstroms resolution To Be Published
8W9T	Structure of TaHKT2;1 in NaCl at 2.6 Angstroms resolution Descriptor: HKT2, SODIUM ION Authors: Wang, J.Q. Deposit date: 2023-09-05 Release date: 2024-02-14 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structure of TaHKT2;1 in NaCl at 2.6 Angstroms resolution To Be Published
8W9J	Crystal structure of human CLEC12A ectodomain complexed with 50C1 Fab Descriptor: Anti-human CLEC12A antibody 50C1 heavy chain, Anti-human CLEC12A antibody 50C1 light chain, C-type lectin domain family 12 member A Authors: Mori, S, Nagae, M, Yamasaki, S. Deposit date: 2023-09-05 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. Int.Immunol., 2024
8QFX	Human Angiotensin-1 converting enzyme N-domain in complex with the lactotripeptide IPP Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Gregory, K.S, Acharya, K.R, Cozier, G.E. Deposit date: 2023-09-05 Release date: 2023-11-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insights into the inhibitory mechanism of angiotensin-I-converting enzyme by the lactotripeptides IPP and VPP. Febs Lett., 598, 2024
8QFL	Ergothioneine dioxygenase from Thermocatellispora tengchongensis in complex with iron Descriptor: ACETATE ION, Cysteine dioxygenase, FE (III) ION, ... Authors: Vasseur, C.M, Seebeck, F.P. Deposit date: 2023-09-04 Release date: 2023-12-27 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Enzyme-Catalyzed Oxidative Degradation of Ergothioneine. Angew.Chem.Int.Ed.Engl., 63, 2024
8QFN	Ergothioneine dioxygenase from Thermocatellispora tengchongensis in complex with manganese and in presence of catalase aerobic Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Cysteine dioxygenase, ... Authors: Vasseur, C.M, Seebeck, F.P. Deposit date: 2023-09-04 Release date: 2023-12-27 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Enzyme-Catalyzed Oxidative Degradation of Ergothioneine. Angew.Chem.Int.Ed.Engl., 63, 2024
8QFP	Ergothioneine dioxygenase from Thermocatellispora tengchongensis in complex with manganese and in presence of catalase anaerobic Descriptor: CHLORIDE ION, Cysteine dioxygenase, MAGNESIUM ION, ... Authors: Vasseur, C.M, Seebeck, F.P. Deposit date: 2023-09-04 Release date: 2023-12-27 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Enzyme-Catalyzed Oxidative Degradation of Ergothioneine. Angew.Chem.Int.Ed.Engl., 63, 2024
8QFQ	Ergothioneine dioxygenase, variant H147A, from Thermocatellispora tengchongensis in complex with manganese Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Cysteine dioxygenase, ... Authors: Vasseur, C.M, Seebeck, F.P. Deposit date: 2023-09-04 Release date: 2023-12-27 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Enzyme-Catalyzed Oxidative Degradation of Ergothioneine. Angew.Chem.Int.Ed.Engl., 63, 2024
8QFM	Ergothioneine dioxygenase from Thermocatellispora tengchongensis in complex with manganese Descriptor: 1,2-ETHANEDIOL, Cysteine dioxygenase, DI(HYDROXYETHYL)ETHER, ... Authors: Vasseur, C.M, Seebeck, F.P. Deposit date: 2023-09-04 Release date: 2023-12-27 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Enzyme-Catalyzed Oxidative Degradation of Ergothioneine. Angew.Chem.Int.Ed.Engl., 63, 2024
8QFO	Ergothioneine dioxygenase, variant Y149F, from Thermocatellispora tengchongensis in complex with manganese Descriptor: ACETATE ION, Cysteine dioxygenase, DI(HYDROXYETHYL)ETHER, ... Authors: Vasseur, C.M, Seebeck, F.P. Deposit date: 2023-09-04 Release date: 2023-12-27 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Enzyme-Catalyzed Oxidative Degradation of Ergothioneine. Angew.Chem.Int.Ed.Engl., 63, 2024
8QFD	UFL1 E3 ligase bound 60S ribosome Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Makhlouf, L, Kulathu, Y, Zeqiraj, E. Deposit date: 2023-09-04 Release date: 2024-02-21 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
8U1S	A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-393 heavy chain, ... Authors: Ferguson, J.A, Raghavan, S.S.R, Ward, A.B. Deposit date: 2023-09-02 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface To Be Published

<78910111213141516171819202122>