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6B2G	P38A mutant of HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-20 Release date: 2018-09-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.407 Å) Cite: Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
6AYA	Structure of the native full-length HIV-1 capsid protein in complex with Nup153 peptide Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ... Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
6AY9	Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide Descriptor: CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein, ... Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
6AXY	Structure of the V11I/T58A/I124A mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Identification of a novel element in HIV-1 capsid critical for assembly and maturation To be published
6AXX	Structure of the T58A/I124A mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Identification of a novel element in HIV-1 capsid critical for assembly and maturation To be published
6AXW	Structure of the I124A mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation. MBio, 9, 2018
6AXV	Structure of the T58S/T107I/P122A mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74) Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ... Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Identification of a novel element in HIV-1 capsid critical for assembly and maturation To be published
6AXT	Structure of the T58S/T107I/P122A mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Identification of a novel element in HIV-1 capsid critical for assembly and maturation To be published
6AXS	Structure of the V11I/T58A/P122A mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.402 Å) Cite: Identification of a novel element in HIV-1 capsid critical for assembly and maturation To be published
6AXR	Structure of the P122A mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-09-07 Release date: 2018-09-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation. MBio, 9, 2018
6ATE	SRC kinase bound to covalent inhibitor Descriptor: N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide, Proto-oncogene tyrosine-protein kinase Src Authors: Gurbani, D, Westover, K.D. Deposit date: 2017-08-28 Release date: 2019-02-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.402 Å) Cite: Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chem Biol, 26, 2019
5YWC	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWA	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A) Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW9	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A) Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (5 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW8	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A) Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YT3	Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 S218D and S222D mutant Descriptor: MAGNESIUM ION, Mitogen-activated protein kinase kinase 1, isoform CRA_d, ... Authors: Nakae, S, Doko, K, Tada, T, Shirai, T. Deposit date: 2017-11-16 Release date: 2018-11-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 S218D and S222D mutant To Be Published
5YKG	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A) Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... Authors: Chen, L, Wu, J.X. Deposit date: 2017-10-14 Release date: 2018-04-18 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (4.57 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YKF	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D class1 at 4.33A) Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... Authors: Chen, L, Wu, J.X. Deposit date: 2017-10-14 Release date: 2018-04-18 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (4.33 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YKE	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A) Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11 Authors: Chen, L, Wu, J.X. Deposit date: 2017-10-14 Release date: 2018-04-18 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (4.11 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YI4	Solution Structure of the DISC1/Ndel1 complex Descriptor: Disrupted in schizophrenia 1 homolog,Nuclear distribution protein nudE-like 1 Authors: Ye, F, Yu, C, Yu, C, Zhang, M. Deposit date: 2017-10-02 Release date: 2017-11-15 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis. Neuron, 96, 2017
5WVC	Structure of the CARD-CARD disk Descriptor: Apoptotic protease-activating factor 1, Caspase, IODIDE ION Authors: Lin, S.C, Lo, Y.C, Su, T.W. Deposit date: 2016-12-24 Release date: 2017-04-19 Method: X-RAY DIFFRACTION (2.993 Å) Cite: Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome. Structure, 25, 2017
5WUA	Structure of a Pancreatic ATP-sensitive Potassium Channel Descriptor: ATP-sensitive inward rectifier potassium channel 11,superfolder GFP, SUR1 Authors: Li, N, Wu, J.-X, Chen, L, Gao, N. Deposit date: 2016-12-16 Release date: 2017-01-25 Method: ELECTRON MICROSCOPY (5.6 Å) Cite: Structure of a Pancreatic ATP-Sensitive Potassium Channel Cell, 168, 2017
5WP1	Complex of ERK2 with 5,7-dihydroxychromone Descriptor: 5,7-dihydroxy-4H-1-benzopyran-4-one, BENZOIC ACID, Mitogen-activated protein kinase 1, ... Authors: Kurinov, I, Malakhova, M. Deposit date: 2017-08-03 Release date: 2018-08-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Multiple phytochemicals at low doses accumulatively inhibit one key protein in cancers To Be Published
5W4Q	Structure of the R18A/E28A mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, Capsid protein p24, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-06-12 Release date: 2018-06-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.285 Å) Cite: Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket. MBio, 10, 2019
5W4P	Structure of the E28A mutant of the HIV-1 capsid protein Descriptor: CHLORIDE ION, Capsid protein p24, IODIDE ION Authors: Gres, A.T, Kirby, K.A, Sarafianos, S.G. Deposit date: 2017-06-12 Release date: 2018-06-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket. MBio, 10, 2019

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