PDB: 10907 resultsInfo pagesStatus searchChemie searchBIRD

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8UJY	Crystal structure of human WD repeat-containing protein 5 in complex with 4-(3,5-dimethoxybenzyl)-9-(4-fluoro-2-methylphenyl)-7-((2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl)methyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (compound 8) Descriptor: (9P)-4-[(3,5-dimethoxyphenyl)methyl]-9-(4-fluoro-2-methylphenyl)-7-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}-3,4-dihydro-1,4-benzoxazepin-5(2H)-one, WD repeat-containing protein 5 Authors: Zhao, B, Amporndanai, K, Fesik, S.W. Deposit date: 2023-10-11 Release date: 2023-12-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors. J.Med.Chem., 66, 2023
8UFT	Structure of human endothelial nitric oxide synthase P370N mutant heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine Descriptor: (7M)-4-methyl-7-(4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)quinolin-2-amine, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, ... Authors: Li, H, Poulos, T.L. Deposit date: 2023-10-04 Release date: 2024-03-13 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase. Biochemistry, 63, 2024
8UFM	Crystal Structure of L516C/Y647C Mutant of SARS-Unique Domain (SUD) from SARS-CoV-2 Descriptor: ACETATE ION, FORMIC ACID, Papain-like protease nsp3, ... Authors: Minasov, G, Shuvalova, L, Brunzelle, J.S, Rosas-Lemus, M, Kiryukhina, O, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) Deposit date: 2023-10-04 Release date: 2023-10-18 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal Structure of L516C/Y647C Mutant of SARS-Unique Domain (SUD) from SARS-CoV-2 To Be Published
8U8T	Y229F/V290N Streptomyces coelicolor Laccase Descriptor: BORIC ACID, COPPER (II) ION, Copper oxidase, ... Authors: Wang, J.-X, Lu, Y. Deposit date: 2023-09-18 Release date: 2023-11-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations. Angew.Chem.Int.Ed.Engl., 62, 2023
8U8S	Y229F/S292F Streptomyces coelicolor Laccase Descriptor: BORIC ACID, COPPER (II) ION, Copper oxidase, ... Authors: Wang, J.-X, Lu, Y. Deposit date: 2023-09-18 Release date: 2023-11-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.63 Å) Cite: Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations. Angew.Chem.Int.Ed.Engl., 62, 2023
8U8R	Y229F/V290N/S292F Streptomyces coelicolor Laccase Descriptor: BORIC ACID, COPPER (II) ION, Copper oxidase, ... Authors: Wang, J.-X, Lu, Y. Deposit date: 2023-09-18 Release date: 2023-11-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations. Angew.Chem.Int.Ed.Engl., 62, 2023
8U8Q	V290N/S292F Streptomyces coelicolor Laccase Descriptor: BORIC ACID, COPPER (II) ION, Copper oxidase, ... Authors: Wang, J.-X, Lu, Y. Deposit date: 2023-09-18 Release date: 2023-11-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations. Angew.Chem.Int.Ed.Engl., 62, 2023
8U8P	S292F Streptomyces coelicolor Laccase Descriptor: BORIC ACID, COPPER (II) ION, Copper oxidase, ... Authors: Wang, J.-X, Lu, Y. Deposit date: 2023-09-18 Release date: 2023-11-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations. Angew.Chem.Int.Ed.Engl., 62, 2023
8U5E	Crystal Structure of C-terminal domain of Clostridium perfringens Enterotoxin in Space Group P 21 21 21 Descriptor: ACETATE ION, GLYCEROL, Heat-labile enterotoxin B chain, ... Authors: Kapoor, S, Vecchio, A.J. Deposit date: 2023-09-12 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin. Toxins, 15, 2023
8U5D	Crystal Structure of C-terminal domain of Clostridium perfringens Enterotoxin in Space Group P 41 21 2 Descriptor: ACETATE ION, GLYCEROL, Heat-labile enterotoxin B chain, ... Authors: Kapoor, S, Vecchio, A.J. Deposit date: 2023-09-12 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin. Toxins, 15, 2023
8U2M	Structure of P450Blt from Micromonospora sp. MW-13 in Complex with Biarylitide Descriptor: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, ACETATE ION, Cytochrome P450-SU1, ... Authors: Hansen, M.H, Cryle, M.J. Deposit date: 2023-09-06 Release date: 2024-01-10 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis Acs Catalysis, 2024
8U1W	Structure of Norovirus (Hu/GII.4/Sydney/NSW0514/2012/AU) protease bound to inhibitor NV-004 Descriptor: ACETATE ION, GLYCEROL, Peptidase C37, ... Authors: Eruera, A.R, Campbell, A.C, Krause, K.L. Deposit date: 2023-09-03 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Crystal Structure of Inhibitor-Bound GII.4 Sydney 2012 Norovirus 3C-Like Protease. Viruses, 15, 2023
8U14	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 2) Descriptor: DNA (146-MER), DNA (147-MER), E3 ubiquitin-protein ligase RNF168, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-30 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8U13	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 1) Descriptor: DNA (146-MER), DNA (147-MER), E3 ubiquitin-protein ligase RNF168, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-30 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8U01	Crystal Structure of the Glycoside Hydrolase Family 2 TIM Barrel-domain Containing Protein from Phocaeicola plebeius Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ... Authors: Kim, Y, Joachimiak, G, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2023-08-28 Release date: 2023-09-27 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal Structure of the Glycoside Hydrolase Family 2 TIM Barrel-domain Containing Protein from Phocaeicola plebeius To Be Published
8TXX	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 3) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-24 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8TXW	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 2) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-24 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8TXV	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 1) Descriptor: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... Authors: Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. Deposit date: 2023-08-24 Release date: 2024-01-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8TWD	Structure of IraM-bound RssB Descriptor: ACETATE ION, Anti-adapter protein IraM, Regulator of RpoS Authors: Brugger, C, Deaconescu, A.M. Deposit date: 2023-08-20 Release date: 2024-01-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.3 Å) Cite: IraM remodels the RssB segmented helical linker to stabilize sigma s against degradation by ClpXP. J.Biol.Chem., 300, 2023
8TS5	Structure of the apo FabS1C_C1 Descriptor: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... Authors: Singer, A.U, Bruce, H.A, Blazer, L.L, Adams, J.J, Sicheri, F, Sidhu, S.S. Deposit date: 2023-08-10 Release date: 2023-11-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
8TOF	Rpd3S bound to an H3K36Cme3 modified nucleosome Descriptor: Chromatin modification-related protein EAF3, DNA (176-MER), Histone H2A, ... Authors: Markert, J.W, Vos, S.M, Farnung, L. Deposit date: 2023-08-03 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex. Nat Commun, 14, 2023
8TNS	Solution structure of poly(UG) RNA (GU)12 G-quadruplex Descriptor: RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*U)-3') Authors: Escobar, C.A, Petersen, R, Butcher, S.E. Deposit date: 2023-08-02 Release date: 2023-11-15 Last modified: 2024-05-15 Method: SOLUTION NMR, SOLUTION SCATTERING Cite: Solution Structure of Poly(UG) RNA. J.Mol.Biol., 435, 2023
8THU	Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1 Descriptor: DNA (145-MER), DNA (146-MER), Histone H2A.Z, ... Authors: Abini-Agbomson, S, Armache, K.-J. Deposit date: 2023-07-18 Release date: 2023-09-06 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. Mol.Cell, 83, 2023
8TFG	1.88A CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TOPOISOMERASE I Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DNA topoisomerase 1 Authors: Tan, K, Tse-Dinh, Y.C. Deposit date: 2023-07-11 Release date: 2023-08-09 Method: X-RAY DIFFRACTION (1.88 Å) Cite: 1.88A CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TOPOISOMERASE I To Be Published
8TFF	PorX with BeF3 phosphate analog Descriptor: ACETATE ION, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... Authors: Saran, A, Zeytuni, N. Deposit date: 2023-07-11 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.34 Å) Cite: PorX with BeF3 phosphate analog To Be Published

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